Description

• General description: Vitamin K1, also known as phylloquinone, consists of naphthalenoid and phytyl groups.[1] Phylloquinone is present abundantly in photosynthetic plants and is a major dietary source.[2] It is a fat-soluble vitamin.[3]
• Application: <ul><li><strong>Nutritional strategies for musculoskeletal health:</strong> Nutritional strategies, including Vitamin K1, optimize musculoskeletal health for fall and fracture prevention beyond traditional nutrients like calcium and vitamin D (Webster et al., 2023 doi:10.1016/j.bonr.2023.101684).</li><li><strong>Role in coagulation and bone health:</strong> A comprehensive review highlights Vitamin K1′s role in reducing cardiovascular risks and details its biochemical interactions affecting coagulation and bone health (Zhao et al., 2024 doi:10.1017/jns.2023.106).</li></ul>
• Biochem/physiol Actions: Vitamin K1 (Phylloquinone) is a lipid soluble polycyclic aromatic ketone used as a cofactor in the formation of coagulation factors II (prothrombin), VII, IX and X; anticoagulant factors protein C and S and as a cell signaling factor.
• Packaging: Bottomless glass bottle. Contents are inside inserted fused cone.
• Other Notes: Review: Vitamin K and γ-carboxyglutamate biosynthesis[5]; Metabolic functions and mechanism of action[6]