A4377

S-(5′-Adenosyl)-L-methionine iodide

≥80% (spectrophotometric assay), suitable for cell culture

Manufacturer: Sigma Aldrich

CAS Number: 3493-13-8

Synonym(S): AdoMet, SAM

Select a Size

Pack Size SKU Availability Price
5 MG A4377-5-MG In Stock ₹ 6,917.18
25 MG A4377-25-MG In Stock ₹ 19,571.60
100 MG A4377-100-MG In Stock ₹ 46,569.15

A4377 - 5 MG

₹ 6,917.18

In Stock

Quantity

1

Base Price: ₹ 6,917.18

GST (18%): ₹ 1,245.092

Total Price: ₹ 8,162.272

Quality Level

200

Assay

≥80% (HPLC)≥80% (spectrophotometric assay)

form

powder

technique(s)

cell culture | mammalian: suitable

color

white to off-white

solubility

H2O: 100 mg/mL

shipped in

dry ice

storage temp.

−20°C

SMILES string

[I-].C[S+](CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(N)ncnc23

InChI

1S/C15H22N6O5S.HI/c1-27(3-2-7(16)15(24)25)4-8-10(22)11(23)14(26-8)21-6-20-9-12(17)18-5-19-13(9)21;/h5-8,10-11,14,22-23H,2-4,16H2,1H3,(H2-,17,18,19,24,25);1H/t7-,8+,10+,11+,14+,27?;/m0./s1

Other Options

Image Product Name Manufacturer Price Range
50-179-7103
Sigma Aldrich Fine Chemicals Biosciences S-(5′-Adenosyl)-L-methionine iodide | 3493-13-8 | MFCD00043192 | 5 mg
Sigma Aldrich Fine Chemicals Biosciences ₹ 8,699.74
50-179-7102
Sigma Aldrich Fine Chemicals Biosciences S-(5′-Adenosyl)-L-methionine iodide 80% (HPLC), 80% (spectrophotometric assay) | 3493-13-8 | MFCD00043192 | 25mg
Sigma Aldrich Fine Chemicals Biosciences ₹ 24,735.40
A4377
S-(5′-Adenosyl)-L-methionine iodide
Sigma Aldrich ₹ 6,917.18 - ₹ 46,569.15
AR00C03Q
S-ADENOSYL-L-METHIONINE IODIDE SALT
Aaron Chemicals LLC ₹ 6,930.36 - ₹ 95,228.28
AF58906
3493-13-8 | 5'-[[(3S)-3-Amino-3-carboxypropyl]methylsulfonio]-5'-deoxy-Adenosine iodide
A2B Chem ₹ 4,278.00

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Description

  • Application: S-(5′-Adenosyl)-L-methionine (SAM, AdoMet) is used as a primary methyl donor molecule in mammalian cell culture and the first step metabolite in methionine biosynthesis.
  • Biochem/physiol Actions: Methyl donor; cofactor for enzyme-catalyzed methylations, including catechol O-methyltransferase (COMT) and DNA methyltransferases (DNMT). Although present in all cells, it is concentrated in liver where 85% of all methylation reactions occur. It is also involved in regulating liver function, growth, and response to injury.
  • Caution: This material is very unstable at room temperature.
  • Analysis Note: Purity based on UV and HPLC.

SAFETY INFORMATION

Pictograms

GHS07

Signal Word

Warning

Hazard Statements

H317

Precautionary Statements

P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364

Hazard Classifications

Skin Sens. 1

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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≥80% (spectrophotometric assay), su...


Quality Level:
200

Assay:
≥80% (HPLC)≥80% (spectrophotometric assay)

form:
powder

technique(s):
cell culture | mammalian: suitable

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white to off-white

solubility:
H2O: 100 mg/mL

shipped in:
dry ice

storage temp.:
−20°C

SMILES string:
[I-].C[S+](CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(N)ncnc23

InChI:
1S/C15H22N6O5S.HI/c1-27(3-2-7(16)15(24)25)4-8-10(22)11(23)14(26-8)21-6-20-9-12(17)18-5-19-13(9)21;/h5-8,10-11,14,22-23H,2-4,16H2,1H3,(H2-,17,18,19,24,25);1H/t7-,8+,10+,11+,14+,27?;/m0./s1

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N.N.O.O.O.O.OB1OB(O1)OB2OB(O)O2

InChI:
1S/B4H2O7.2H3N.4H2O/c5-1-7-3(8-1)11-4-9-2(6)10-4;;;;;;/h5-6H;2*1H3;4*1H2

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[Na].CC(=O)NC1C(O)OC(COP(O)(O)=O)C(O)C1O

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