A8054

D(−)-2-Amino-5-phosphonopentanoic acid

NMDA receptor antagonist

Manufacturer: Sigma Aldrich

CAS Number: 79055-68-8

Synonym(S): D(−)-AP-5, D(−)-APV, D-2-Amino-5-phosphonovaleric acid

Select a Size

Pack Size SKU Availability Price
1 MG A8054-1-MG In Stock ₹ 5,450.00
5 MG A8054-5-MG In Stock ₹ 17,970.00
10 MG A8054-10-MG In Stock ₹ 33,200.00

A8054 - 1 MG

₹ 5,450.00

In Stock

Quantity

1

Base Price: ₹ 5,450.00

GST (18%): ₹ 981.00

Total Price: ₹ 6,431.00

Quality Level

100

Assay

≥98% (TLC)

form

powder

optical purity

optical purity: ≥90% (HPLC, Marfey′s reagent)

technique(s)

ligand binding assay: suitable

color

white

mp

245-246 °C

SMILES string

N[C@H](CCCP(O)(O)=O)C(O)=O

InChI

1S/C5H12NO5P/c6-4(5(7)8)2-1-3-12(9,10)11/h4H,1-3,6H2,(H,7,8)(H2,9,10,11)/t4-/m1/s1

InChI key

VOROEQBFPPIACJ-SCSAIBSYSA-N

Other Options

Image Product Name Manufacturer Price Range
NC1368401
Cayman Chemical D-AP5, 79055-68-8, 10 mg
Cayman Chemical ₹ 9,839.40
501786516
Sigma Aldrich Fine Chemicals Biosciences D(-)-2-Amino-5-phosphonopentanoic acid NMDA receptor antagonist | 79055-68-8 | MFCD00078839 | 1MG
Sigma Aldrich Fine Chemicals Biosciences ₹ 9,841.97
NC1495262
Enzo Life Sciences D-AP5, (5mg), CAS Number: 79055-68-8
Enzo Life Sciences ₹ 12,004.07
A8054
D(−)-2-Amino-5-phosphonopentanoic acid
Sigma Aldrich ₹ 5,450.00 - ₹ 33,200.00
AR003317
(R)-2-Amino-5-phosphonopentanoic acid
Aaron Chemicals LLC ₹ 2,823.48 - ₹ 35,336.28
AB42799
79055-68-8 | (R)-2-Amino-5-phosphonopentanoic acid
A2B Chem ₹ 4,449.12 - ₹ 50,565.96

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Description

  • Application: D(-)-2-Amino-5-phosphonopentanoic acid has been used to pretreat BNST (bed nucleus of the stria terminalis) in order to block the induction of anxiety by ORX-A (orexin-A) into the BNST.[1]
  • Biochem/physiol Actions: NMDA antagonists have muscle relaxation property and are known to offer neuron protection against brain damage induced by ischemia. 2-Amino-5-phosphonopentanoic acid has been proved to block the iontophoresis induced depolarization of NMDA.[2]

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Quality Level:
100

Assay:
≥98% (TLC)

form:
powder

optical purity:
optical purity: ≥90% (HPLC, Marfey′s reagent)

technique(s):
ligand binding assay: suitable

color:
white

mp:
245-246 °C

SMILES string:
N[C@H](CCCP(O)(O)=O)C(O)=O

InChI:
1S/C5H12NO5P/c6-4(5(7)8)2-1-3-12(9,10)11/h4H,1-3,6H2,(H,7,8)(H2,9,10,11)/t4-/m1/s1

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VOROEQBFPPIACJ-SCSAIBSYSA-N

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InChI:
1S/C7H7NO4/c1-2-7(11)12-8-5(9)3-4-6(8)10/h2H,1,3-4H2

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YXMISKNUHHOXFT-UHFFFAOYSA-N

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__