A8674
Antimycin A from Streptomyces sp.
Manufacturer: Sigma Aldrich
CAS Number: 1397-94-0
Synonym(S): Antipiricullin
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 25 MG | A8674-25-MG | In Stock | ₹ 9,406.93 |
| 50 MG | A8674-50-MG | In Stock | ₹ 15,588.00 |
| 100 MG | A8674-100-MG | In Stock | ₹ 26,120.73 |
A8674 - 25 MG
In Stock
Quantity
1
Base Price: ₹ 9,406.93
GST (18%): ₹ 1,693.247
Total Price: ₹ 11,100.177
form
powder
Quality Level
300
antibiotic activity spectrum
fungi
Mode of action
enzyme | inhibits
storage temp.
−20°C
SMILES string
[H]C(=O)Nc1cccc(C(=O)N[C@H]2[C@@H](C)OC(=O)C(CCCCCC)[C@@H](OC(=O)CC(C)C)[C@H](C)OC2=O)c1O
InChI
1S/C28H40N2O9/c1-6-7-8-9-11-20-25(39-22(32)14-16(2)3)18(5)38-28(36)23(17(4)37-27(20)35)30-26(34)19-12-10-13-21(24(19)33)29-15-31/h10,12-13,15-18,20,23,25,33H,6-9,11,14H2,1-5H3,(H,29,31)(H,30,34)/t17-,18+,20?,23+,25+/m1/s1
InChI key
UIFFUZWRFRDZJC-RBVQMQRASA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Antimycin A from Streptomyces sp. | Sigma Aldrich | ₹ 9,406.93 - ₹ 26,120.73 |
Related Products
Description
- General description: Antimycin is an antibiotic[1] produced by Streptomyces species. [2] It inhibits mitochondrial electron transport chain complex III and favors reactive oxygen species (ROS) production, impairing mitochondrial depolarization.[3] It inhibits nitric oxide-mediated apoptosis and modulatescytochrome C release.[4] It suppresses tumorigenesis in lung cancer cells and could be a potential therapeutic agent.[5]Antimycin A serves as a positive control for superoxide generation.
- Application: Antimycin A from Streptomyces sp. has been used:as a respiratory chain inhibitor in neuronal cultures[6][7]in organello ATP production assay in Trypanosoma brucei cells[8]in respiration assay for papillary thyroid carcinoma (PTC) cell lines[9]
- Biochem/physiol Actions: Inhibitor of electron transfer at complex III. Induces apoptosis.
- Quality: A mixture of antimycins.
- Other Notes: 2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 2 Oral - Aquatic Acute 1
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Compare Similar Items
Show Difference
form: powder
Quality Level: 300
antibiotic activity spectrum: fungi
Mode of action: enzyme | inhibits
storage temp.: −20°C
SMILES string: [H]C(=O)Nc1cccc(C(=O)N[C@H]2[C@@H](C)OC(=O)C(CCCCCC)[C@@H](OC(=O)CC(C)C)[C@H](C)OC2=O)c1O
InChI: 1S/C28H40N2O9/c1-6-7-8-9-11-20-25(39-22(32)14-16(2)3)18(5)38-28(36)23(17(4)37-27(20)35)30-26(34)19-12-10-13-21(24(19)33)29-15-31/h10,12-13,15-18,20,23,25,33H,6-9,11,14H2,1-5H3,(H,29,31)(H,30,34)/t17-,18+,20?,23+,25+/m1/s1
InChI key: UIFFUZWRFRDZJC-RBVQMQRASA-N
form:
powder
Quality Level:
300
antibiotic activity spectrum:
fungi
Mode of action:
enzyme | inhibits
storage temp.:
−20°C
SMILES string:
[H]C(=O)Nc1cccc(C(=O)N[C@H]2[C@@H](C)OC(=O)C(CCCCCC)[C@@H](OC(=O)CC(C)C)[C@H](C)OC2=O)c1O
InChI:
1S/C28H40N2O9/c1-6-7-8-9-11-20-25(39-22(32)14-16(2)3)18(5)38-28(36)23(17(4)37-27(20)35)30-26(34)19-12-10-13-21(24(19)33)29-15-31/h10,12-13,15-18,20,23,25,33H,6-9,11,14H2,1-5H3,(H,29,31)(H,30,34)/t17-,18+,20?,23+,25+/m1/s1
InChI key:
UIFFUZWRFRDZJC-RBVQMQRASA-N
form: solid
Quality Level: 200
antibiotic activity spectrum: __
Mode of action: __
storage temp.: __
SMILES string: Nc1ccccc1S(O)(=O)=O
InChI: 1S/C6H7NO3S/c7-5-3-1-2-4-6(5)11(8,9)10/h1-4H,7H2,(H,8,9,10)
InChI key: ZMCHBSMFKQYNKA-UHFFFAOYSA-N
form:
solid
Quality Level:
200
antibiotic activity spectrum:
__
Mode of action:
__
storage temp.:
__
SMILES string:
Nc1ccccc1S(O)(=O)=O
InChI:
1S/C6H7NO3S/c7-5-3-1-2-4-6(5)11(8,9)10/h1-4H,7H2,(H,8,9,10)
InChI key:
ZMCHBSMFKQYNKA-UHFFFAOYSA-N
form: powder
Quality Level: 200
antibiotic activity spectrum: __
Mode of action: __
storage temp.: −20°C
SMILES string: [Na+].[H]C(=O)[C@H](O)[C@@H](O)[C@H](O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O[C@@]2(C[C@H](O)[C@@H](NC(C)=O)[C@@H](O2)[C@H](O)[C@H](O)CO)C([O-])=O)[C@H]1O)[C@H](O)CO
InChI: 1S/C23H39NO19.Na/c1-7(29)24-13-8(30)2-23(22(38)39,42-19(13)15(35)10(32)4-26)43-20-16(36)12(6-28)40-21(17(20)37)41-18(11(33)5-27)14(34)9(31)3-25;/h3,8-21,26-28,30-37H,2,4-6H2,1H3,(H,24,29)(H,38,39);/q;+1/p-1/t8-,9-,10+,11+,12+,13+,14+,15+,16-,17+,18+,19+,20-,21-,23-;/m0./s1
InChI key: __
form:
powder
Quality Level:
200
antibiotic activity spectrum:
__
Mode of action:
__
storage temp.:
−20°C
SMILES string:
[Na+].[H]C(=O)[C@H](O)[C@@H](O)[C@H](O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O[C@@]2(C[C@H](O)[C@@H](NC(C)=O)[C@@H](O2)[C@H](O)[C@H](O)CO)C([O-])=O)[C@H]1O)[C@H](O)CO
InChI:
1S/C23H39NO19.Na/c1-7(29)24-13-8(30)2-23(22(38)39,42-19(13)15(35)10(32)4-26)43-20-16(36)12(6-28)40-21(17(20)37)41-18(11(33)5-27)14(34)9(31)3-25;/h3,8-21,26-28,30-37H,2,4-6H2,1H3,(H,24,29)(H,38,39);/q;+1/p-1/t8-,9-,10+,11+,12+,13+,14+,15+,16-,17+,18+,19+,20-,21-,23-;/m0./s1
InChI key:
__
form: powder
Quality Level: 200
antibiotic activity spectrum: __
Mode of action: __
storage temp.: −20°C
SMILES string: [Na+].[H]C(=O)[C@H](O)[C@@H](O)[C@H](O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O[C@@]2(C[C@H](O)[C@@H](NC(C)=O)[C@@H](O2)[C@H](O)[C@H](O)CO)C([O-])=O)[C@H]1O)[C@H](O)CO
InChI: 1S/C23H39NO19.Na/c1-7(29)24-13-8(30)2-23(22(38)39,42-19(13)15(35)10(32)4-26)43-20-16(36)12(6-28)40-21(17(20)37)41-18(11(33)5-27)14(34)9(31)3-25;/h3,8-21,26-28,30-37H,2,4-6H2,1H3,(H,24,29)(H,38,39);/q;+1/p-1/t8-,9-,10+,11+,12+,13+,14+,15+,16-,17+,18+,19+,20-,21-,23-;/m0./s1
InChI key: __
form:
powder
Quality Level:
200
antibiotic activity spectrum:
__
Mode of action:
__
storage temp.:
−20°C
SMILES string:
[Na+].[H]C(=O)[C@H](O)[C@@H](O)[C@H](O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O[C@@]2(C[C@H](O)[C@@H](NC(C)=O)[C@@H](O2)[C@H](O)[C@H](O)CO)C([O-])=O)[C@H]1O)[C@H](O)CO
InChI:
1S/C23H39NO19.Na/c1-7(29)24-13-8(30)2-23(22(38)39,42-19(13)15(35)10(32)4-26)43-20-16(36)12(6-28)40-21(17(20)37)41-18(11(33)5-27)14(34)9(31)3-25;/h3,8-21,26-28,30-37H,2,4-6H2,1H3,(H,24,29)(H,38,39);/q;+1/p-1/t8-,9-,10+,11+,12+,13+,14+,15+,16-,17+,18+,19+,20-,21-,23-;/m0./s1
InChI key:
__