Cefmetazole sodium salt
Manufacturer: Sigma Aldrich
CAS Number: 56796-39-5
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 G | C6048-1-G | In Stock | ₹ 11,777.60 |
C6048 - 1 G
In Stock
Quantity
1
Base Price: ₹ 11,777.60
GST (18%): ₹ 2,119.968
Total Price: ₹ 13,897.568
form
powder
Quality Level
200
shelf life
limited shelf life, expiry date on the label
solubility
H2O: 50 mg/mL
antibiotic activity spectrum
Gram-negative bacteriaGram-positive bacteria
Mode of action
cell wall synthesis | interferes
storage temp.
2-8°C
SMILES string
[Na+].[H][C@]12SCC(CSc3nnnn3C)=C(N1C(=O)[C@]2(NC(=O)CSCC#N)OC)C([O-])=O
InChI
1S/C15H17N7O5S3.Na/c1-21-14(18-19-20-21)30-6-8-5-29-13-15(27-2,17-9(23)7-28-4-3-16)12(26)22(13)10(8)11(24)25;/h13H,4-7H2,1-2H3,(H,17,23)(H,24,25);/q;+1/p-1/t13-,15+;/m1./s1
InChI key
BITQGIOJQWZUPL-PBCQUBLHSA-M
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | 56796-39-5 | 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[[(cyanomethyl)thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, monosodium salt, (6R,7S)- | A2B Chem | ₹ 8,983.80 - ₹ 1,11,570.24 |
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Description
- General description: Chemical structure: ß-lactam
- Application: Cefmetazole is used to study the effect of expression, binding, and inhibition of penicillin-binding proteins (PDPs) other than PBP2 on bacterial cell wall mucopeptide synthesis. Cefmetazole is used to study protein mediated transport of antibiotics.[1]
- Biochem/physiol Actions: Cefmetazole disrupts the synthesis of the peptidoglycan layer of bacterial cell walls which is responsible for cell wall structural integrity. Peptidoglycan synthesis is facilitated by transpeptidases known as penicillin-binding proteins (PBPs). PBPs bind to the D-Ala-D-Ala at the end of muropeptides (peptidoglycan precursors) to crosslink the peptidoglycan. Cefmetazole mimics the D-Ala-D-Ala site, thereby competitively inhibiting PBP crosslinking of peptidoglycan. It is effective against both Gram-positive and Gram-negative bacteria.
- Packaging: Bottomless glass bottle. Contents are inside inserted fused cone.
- Other Notes: Keep container tightly closed in a dry and well-ventilated place. Hygroscopic Handle and store under inert gas.
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
Hazard Classifications
Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
Target Organs
Respiratory system
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Compare Similar Items
Show Difference
form: powder
Quality Level: 200
shelf life: limited shelf life, expiry date on the label
solubility: H2O: 50 mg/mL
antibiotic activity spectrum: Gram-negative bacteriaGram-positive bacteria
Mode of action: cell wall synthesis | interferes
storage temp.: 2-8°C
SMILES string: [Na+].[H][C@]12SCC(CSc3nnnn3C)=C(N1C(=O)[C@]2(NC(=O)CSCC#N)OC)C([O-])=O
InChI: 1S/C15H17N7O5S3.Na/c1-21-14(18-19-20-21)30-6-8-5-29-13-15(27-2,17-9(23)7-28-4-3-16)12(26)22(13)10(8)11(24)25;/h13H,4-7H2,1-2H3,(H,17,23)(H,24,25);/q;+1/p-1/t13-,15+;/m1./s1
InChI key: BITQGIOJQWZUPL-PBCQUBLHSA-M
form: liquid
Quality Level: 100
shelf life: __
solubility: __
antibiotic activity spectrum: __
Mode of action: __
storage temp.: __
SMILES string: [O-][N+](=O)c1cc(ccc1Cl)C(F)(F)F
InChI: 1S/C7H3ClF3NO2/c8-5-2-1-4(7(9,10)11)3-6(5)12(13)14/h1-3H
InChI key: TZGFQIXRVUHDLE-UHFFFAOYSA-N
form: __
Quality Level: __
shelf life: __
solubility: __
antibiotic activity spectrum: __
Mode of action: __
storage temp.: __
SMILES string: __
InChI: __
InChI key: __