C9393

Cloxacillin sodium salt monohydrate

β-lactamase-resistant antibiotic

Manufacturer: Sigma Aldrich

CAS Number: 7081-44-9

Synonym(S): Cloxacillin, Sodium cloxacillin monohydrate

Select a Size

Pack Size SKU Availability Price
1 G C9393-1-G In Stock ₹ 6,083.65
5 G C9393-5-G In Stock ₹ 16,085.95

C9393 - 1 G

₹ 6,083.65

In Stock

Quantity

1

Base Price: ₹ 6,083.65

GST (18%): ₹ 1,095.057

Total Price: ₹ 7,178.707

Quality Level

200

form

powder or crystals

antibiotic activity spectrum

Gram-positive bacteria

Mode of action

cell wall synthesis | interferes

storage temp.

2-8°C

SMILES string

O.[Na+].Cc1onc(-c2ccccc2Cl)c1C(=O)N[C@H]3[C@H]4SC(C)(C)[C@@H](N4C3=O)C([O-])=O

InChI

1S/C19H18ClN3O5S.Na.H2O/c1-8-11(12(22-28-8)9-6-4-5-7-10(9)20)15(24)21-13-16(25)23-14(18(26)27)19(2,3)29-17(13)23;;/h4-7,13-14,17H,1-3H3,(H,21,24)(H,26,27);;1H2/q;+1;/p-1/t13-,14+,17-;;/m1../s1

InChI key

KCUWTKOTPIUBRI-VICXVTCVSA-M

Other Options

Image Product Name Manufacturer Price Range
11-101-5307
Cloxacillin Sodium Pharmaceutical Secondary Standard, MilliporeSigma™ Supelco™
MilliporeSigma Supelco ₹ 19,336.56
50-176-6349
Sigma Aldrich Fine Chemicals Biosciences Cloxacillin sodium European Pharmacopoeia (EP) Reference Standard | 7081-44-9 | MFCD00150735 |
Sigma Aldrich Fine Chemicals Biosciences ₹ 16,350.52
50-176-6351
Sigma Aldrich Fine Chemicals Biosciences Cloxacillin sodium salt monohydrate beta-lactamase-resistant antibiotic | 7081-44-9 | MFCD00150735 | 5G
Sigma Aldrich Fine Chemicals Biosciences ₹ 27,670.10
46140
Cloxacillin sodium salt monohydrate
Supelco ₹ 6,137.78
PHR1922
Cloxacillin Sodium
Supelco ₹ 18,976.23
C2450000
Cloxacillin sodium
Sigma Aldrich ₹ 14,267.35
C9393
Cloxacillin sodium salt monohydrate
Sigma Aldrich ₹ 6,083.65 - ₹ 16,085.95
AB72194
7081-44-9 | Cloxacillin sodium salt monohydrate
A2B Chem ₹ 3,251.28 - ₹ 9,240.48

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Description

  • General description: Chemical structure: ß-lactam
  • Application: Cloxacillin is effective against infections caused by penicillin G-resistant staphylococci.[1] It was used in studies of topical antibacterial agents for burn and crush wounds.[2]
  • Biochem/physiol Actions: Cloxacillin is a semi-synthetic antibiotic and a chlorinated derivative of oxacillin. It inhibits the last stage of bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), which results in cell lysis. Cell lysis is mediated by bacterial cell wall autolytic enzymes. Cloxacillin is often used as AmpC β-lactamase inhibitor in combination with β-lactam antibiotics.
  • Other Notes: Keep container tightly closed in a dry and well-ventilated place.

SAFETY INFORMATION

Pictograms

GHS08,GHS07

Signal Word

Danger

Hazard Statements

H315,H317,H319,H334,H335

Precautionary Statements

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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200

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Mode of action:
cell wall synthesis | interferes

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SMILES string:
O.[Na+].Cc1onc(-c2ccccc2Cl)c1C(=O)N[C@H]3[C@H]4SC(C)(C)[C@@H](N4C3=O)C([O-])=O

InChI:
1S/C19H18ClN3O5S.Na.H2O/c1-8-11(12(22-28-8)9-6-4-5-7-10(9)20)15(24)21-13-16(25)23-14(18(26)27)19(2,3)29-17(13)23;;/h4-7,13-14,17H,1-3H3,(H,21,24)(H,26,27);;1H2/q;+1;/p-1/t13-,14+,17-;;/m1../s1

InChI key:
KCUWTKOTPIUBRI-VICXVTCVSA-M

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SMILES string:
OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.Clc1ccc(NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)Nc2ccc(Cl)cc2)cc1

InChI:
1S/C22H30Cl2N10.2C6H12O7/c23-15-5-9-17(10-6-15)31-21(27)33-19(25)29-13-3-1-2-4-14-30-20(26)34-22(28)32-18-11-7-16(24)8-12-18;2*7-1-2(8)3(9)4(10)5(11)6(12)13/h5-12H,1-4,13-14H2,(H5,25,27,29,31,33)(H5,26,28,30,32,34);2*2-5,7-11H,1H2,(H,12,13)/t;2*2-,3-,4+,5-/m.11/s1

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__

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CVNOWLNNPYYEOH-UHFFFAOYSA-N

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InChI:
__

InChI key:
__