I1020

Interleukin-4 from mouse

IL-4, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

Manufacturer: Sigma Aldrich

Synonym(S): mIL-4, Interleukin-4 human

Select a Size

Pack Size SKU Availability Price
5 μG I1020-5-μG In Stock ₹ 17,815.50

I1020 - 5 μG

₹ 17,815.50

In Stock

Quantity

1

Base Price: ₹ 17,815.50

GST (18%): ₹ 3,206.79

Total Price: ₹ 21,022.29

biological source

mouse

recombinant

expressed in E. coli

Assay

≥98% (SDS-PAGE)

form

lyophilized powder

potency

0.1-2.0 ng/mL ED50/EC50

quality

endotoxin tested

mol wt

~13.5 kDa

packaging

pkg of 5 μg

technique(s)

cell culture | mammalian: suitable

impurities

<0.1 EU/μg

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Description

  • Application: Interleukin-4 from mouse has been used:as a component of cell culture media for class switch recombination assay[1]to study its therapeutic benefits for mucosal healing[2]as a pioglitazone or new peroxisome proliferator-activated receptor agonist (GQ-11)[3]
  • Biochem/physiol Actions: Interleukin-4 (IL-4) is a lymphokine with profound effects on the growth and differentiation of immunologically competent cells. IL-4 is also known as B cell stimulatory factor-1 (BSF-1), T cell growth factor-2 (TCGF-2) and mast-cell growth factor-2 (MCGF-2). Inhibits VEGF-induced and FGF-Basic-induced angiogenesis. IL-4 is a complex glycoprotein released by a subset of activated T cells. Treatment of IL-4 with specific glycosidases yields an active polypeptide. Human and mouse IL-4 share 50% amino acid sequence homology, but their biological actions are species-specific.
  • Physical form: Lyophilized, 0.2 μm filtered, with no additives.
  • Analysis Note: The proliferative activity is tested in culture using mouse HT-2 cells.[4]

SAFETY INFORMATION

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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biological source:
mouse

recombinant:
expressed in E. coli

Assay:
≥98% (SDS-PAGE)

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lyophilized powder

potency:
0.1-2.0 ng/mL ED50/EC50

quality:
endotoxin tested

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~13.5 kDa

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pkg of 5 μg

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cell culture | mammalian: suitable

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<0.1 EU/μg

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