I2526

Insulin-like Growth Factor-II human

IGF-II, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

Manufacturer: Sigma Aldrich

Synonym(S): IGF-II

Select a Size

Pack Size SKU Availability Price
50 μG I2526-50-μG In Stock ₹ 29,790.40

I2526 - 50 μG

₹ 29,790.40

In Stock

Quantity

1

Base Price: ₹ 29,790.40

GST (18%): ₹ 5,362.272

Total Price: ₹ 35,152.672

biological source

human

Quality Level

200

recombinant

expressed in E. coli

Assay

≥98% (SDS-PAGE and HPLC)

form

lyophilized powder

potency

≤2.0 ng/mL ED50

quality

endotoxin tested

mol wt

7.5 kDa

packaging

pkg of 5X50 μgpkg of 50 μg

technique(s)

cell culture | mammalian: suitable

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Description

  • Biochem/physiol Actions: Insulin-like growth factor II (IGF-II) also known as multiplication stimulating activity (MSA), shows virtually identical bioactivities as IGF-I. Expression of IGF-II is highest in fetal tissues, where it is believed to play a major role in overall growth and development. After birth IGF-II expression decreases to much lower levels in a variety of tissues. IGF-II is produced also in several tumors. IGF-II binds to IGF-II receptor (IGF-IIR), to IGF-IR and weakly to the insulin receptor (IR). All IGF-II bioactivities in adult tissues are generally attributed to its interaction with IGF-IR. However, during embryogenesis the roles of both IGF-IIR and IR may be significant in promoting normal growth.
  • Physical form: Lyophilized from a 0.2 μm filtered solution with no additives.
  • Analysis Note: The biological activity is measured by a cell proliferation assay using mouse FDC-P1

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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