M6518

Macrophage Colony-Stimulating Factor human

M-CSF, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

Manufacturer: Sigma Aldrich

Synonym(S): MCSF

Select a Size

Pack Size SKU Availability Price
10 μG M6518-10-μG In Stock ₹ 34,077.00

M6518 - 10 μG

₹ 34,077.00

In Stock

Quantity

1

Base Price: ₹ 34,077.00

GST (18%): ₹ 6,133.86

Total Price: ₹ 40,210.86

biological source

human

Quality Level

200

recombinant

expressed in E. coli

Assay

≥98% (SDS-PAGE and HPLC)

form

lyophilized powder

potency

0.500-5.000 ng/mL ED50

quality

endotoxin tested

mol wt

dimer 37 kDa

packaging

pkg of 10 μg

technique(s)

cell culture | mammalian: suitable

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Description

  • General description: Macrophage Colony-Stimulating Factor (M-CSF) is a hematopoietic growth factor, which modulates the proliferation, differentiation and functional activation of monocytes.[1] It is produced by fibroblasts, endothelial cells and bone marrow stromal cells.[2] MCSF stimulates the functions of mature monocytes and macrophages.[1]
  • Application: Macrophage Colony-Stimulating Factor human has been used for the differentiation of bone marrow-derived macrophages (BMDMs)[3] and human monocyte-derived macrophages (MDMs).[4] It has also been used for cell culture.[5]
  • Biochem/physiol Actions: Macrophage colony-stimulating factor (M-CSF) augments many of the physiological functions of macrophages, and support osteoclast differentiation.
  • Other Notes: 159 amino acids including N-terminal methionine (each monomer).
  • Physical form: Lyophilized from a sterile filtered buffered solution.
  • Analysis Note: The proliferative activity is tested in culture using the cytokine-dependent murine monocytic cell line M-NFS-60 cells.

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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endotoxin tested

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dimer 37 kDa

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