I2778
Interleukin-1α human
IL-1α, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
Manufacturer: Sigma Aldrich
Synonym(S): IL-1α, hIL-1α., Interleukin-1α human, Lymphocyte activating factor
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 2 μG | I2778-2-μG | In Stock | ₹ 20,490.60 |
I2778 - 2 μG
In Stock
Quantity
1
Base Price: ₹ 20,490.60
GST (18%): ₹ 3,688.308
Total Price: ₹ 24,178.908
biological source
human
Quality Level
100
recombinant
expressed in E. coli
Assay
≥98% (SDS-PAGE and HPLC)
form
lyophilized powder
quality
endotoxin tested
mol wt
~17 kDa
packaging
pkg of 2 and 10 μg
technique(s)
cell culture | mammalian: suitable
UniProt accession no.
P01583
Related Products
Description
- General description: Interleukin-1α (IL-1α) is a cytokine that belongs to the interleukin-1 (IL-1) family.[1] It is located intracellularly in hematopoietic and non-hematopoietic cells.[2] IL-1α gene is located on the human chromosome at 2q14.1.[3]
- Application: Interleukin-1α (IL-1α) has been used:to study its effects on human colorectal adenocarcinoma cells[4]to stimulate primary human fetal retinal pigment epithelium (hfRPE) cells[5]to pre-stimulate human THP-1 monocytes[6]
- Biochem/physiol Actions: Interleukin-1α (IL-1α) plays a crucial role in inflammation during cell necrosis. It also regulates the recruitment of interleukin-1β (IL-1β), neutrophils, chemokines, and other cytokines at the site of injury. IL-1α exhibits a dual function of binding to its cell surface receptor as well as chromatin.[1]
- Physical form: Lyophilized from 0.2 μm filtered 10 mM sodium phosphate , pH 8.0, plus 50 mm NaCl and 50 μg bovine serum albumin (BSA) per μg cytokine.
- Analysis Note: The proliferative activity of human IL-1α is tested in culture using the murine cell line D10S.
SAFETY INFORMATION
Pictograms
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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biological source: human
Quality Level: 100
recombinant: expressed in E. coli
Assay: ≥98% (SDS-PAGE and HPLC)
form: lyophilized powder
quality: endotoxin tested
mol wt: ~17 kDa
packaging: pkg of 2 and 10 μg
technique(s): cell culture | mammalian: suitable
UniProt accession no.: P01583
biological source:
human
Quality Level:
100
recombinant:
expressed in E. coli
Assay:
≥98% (SDS-PAGE and HPLC)
form:
lyophilized powder
quality:
endotoxin tested
mol wt:
~17 kDa
packaging:
pkg of 2 and 10 μg
technique(s):
cell culture | mammalian: suitable
UniProt accession no.:
P01583
biological source: __
Quality Level: 200
recombinant: __
Assay: ≥98%
form: crystalline
quality: __
mol wt: __
packaging: __
technique(s): cell culture | plant: suitable
UniProt accession no.: __
biological source:
__
Quality Level:
200
recombinant:
__
Assay:
≥98%
form:
crystalline
quality:
__
mol wt:
__
packaging:
__
technique(s):
cell culture | plant: suitable
UniProt accession no.:
__
biological source: __
Quality Level: 400
recombinant: __
Assay: __
form: liquid
quality: __
mol wt: __
packaging: __
technique(s): cell culture | hybridoma: suitablecell culture | mammalian: suitable
UniProt accession no.: __
biological source:
__
Quality Level:
400
recombinant:
__
Assay:
__
form:
liquid
quality:
__
mol wt:
__
packaging:
__
technique(s):
cell culture | hybridoma: suitablecell culture | mammalian: suitable
UniProt accession no.:
__
biological source: __
Quality Level: 200
recombinant: __
Assay: ≥99%
form: __
quality: __
mol wt: __
packaging: __
technique(s): __
UniProt accession no.: __
biological source:
__
Quality Level:
200
recombinant:
__
Assay:
≥99%
form:
__
quality:
__
mol wt:
__
packaging:
__
technique(s):
__
UniProt accession no.:
__