I4276

Interferon-αA human

≥95%, suitable for cell culture, buffered aqueous solution, recombinant, expressed in E. coli

Manufacturer: Sigma Aldrich

CAS Number: 105388-21-4

Synonym(S): IFN-αA, Interferon-α2A

Select a Size

Pack Size SKU Availability Price
20 μG I4276-20-μG In Stock ₹ 47,996.40

I4276 - 20 μG

₹ 47,996.40

In Stock

Quantity

1

Base Price: ₹ 47,996.40

GST (18%): ₹ 8,639.352

Total Price: ₹ 56,635.752

biological source

human

Quality Level

200

recombinant

expressed in E. coli

Assay

≥95%

form

buffered aqueous solution

mol wt

19 kDa

packaging

pkg of 20 μg

concentration

≥0.2 mg/mL

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

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Description

  • Application: Interferon-αA human has been used to:study the effect of Chikungunya virus on interferon-mediated JAK (Janus kinase)-STAT (signal transducers and activators of transcription) signaling[1]study the effect of interferon-α and PRK2 (protein kinase C-related kinase 2) inhibitors on hepatitis C virus replication[2]compare the effect of Monascus pigment derivatives on hepatitis C virus replication[3]
  • Biochem/physiol Actions: Cytokine with anti-viral, anti-proliferative, immunoregulatory, and proinflammatory activities. Type I Interferons are a closely related family of 165-172 amino acid proteins that are produced by leukocytes (α subtypes), fibroblasts (β subtypes), lymphocytes (ω subtypes) and ruminant embryos (τ subtypes). Interferon induces a variety of effects on target cells including antiviral, antiproliferative and immunomodulatory activities.
  • Physical form: Supplied as a solution in 5 mM sodium acetate, pH 4.0.
  • Analysis Note: The biological activity is determined in the cytopathic effect inhibition assay using MDBK cells with vesicular stomatitis virus (VSV). A cytopathic effect of 50% is produced with 1 unit/ml interferon. The units are determined with respect to WHO International standard reference for human interferonαA.

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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