I8904

Insulin-like Growth Factor-II from mouse

IGF-II, recombinant, expressed in E. coli, lyophilized powder

Manufacturer: Sigma Aldrich

Synonym(S): IGF-II

Select a Size

Pack Size SKU Availability Price
50 μG I8904-50-μG In Stock ₹ 32,637.38
5 X 50 μG I8904-5-X-50-μG In Stock ₹ 1,30,668.58

I8904 - 50 μG

₹ 32,637.38

In Stock

Quantity

1

Base Price: ₹ 32,637.38

GST (18%): ₹ 5,874.728

Total Price: ₹ 38,512.108

biological source

mouse

Quality Level

100

recombinant

expressed in E. coli

Assay

>97% (SDS-PAGE)

form

lyophilized powder

quality

endotoxin tested

mol wt

~7.4 kDa

packaging

pkg of 5X50 μgpkg of 50 μg

impurities

<1.0EUper1mg (LAL test)

UniProt accession no.

P09535

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Description

  • General description: Recombinant Mouse IGF-II is produced from a DNA sequence encoding the mature IGF-II protein. Mouse IGF-II, a 67 amino acid protein, has a predicted molecular matrix of ~7.4 kDa. Mouse and human IGF-II share 91% sequence homology. Insulin-like growth factor II (also known as multiplication stimulating activity or MSA) and insulin-like growth factor I (IGF-I) belong to the family of insulin-like growth factors, which are structurally homologous to proinsulin. Mature IGF-I and IGF-II are highly conserved and share ~70% amino acid sequence identity. They have autocrine, paracrine, and endocrine functions.
  • Biochem/physiol Actions: Insulin-like growth factor II (IGF-II) is a potent mitogenic growth factor that mediates growth-promoting activities in embryonic development. IGF-II binds the IGF-II receptor with high affinity. IGF-I and IGF II are expressed in many tissues and cell types. IGF-II is mitogenic for a variety of cultured cells including human or chicken fibroblasts, mouse 3T3 cells, normal rat kidney.
  • Physical form: Lyophilized from a 0.2 μm filtered solution of 30% acetonitrile and 0.1% of TFA.
  • Analysis Note: The biological activity is measured in a serum-free cell proliferation assay using the human breast carcinoma cell line MCF-7.

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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lyophilized powder

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endotoxin tested

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~7.4 kDa

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