Methotrexate hydrate
powder, suitable for cell culture, BioReagent
Manufacturer: Sigma Aldrich
CAS Number: 133073-73-1
Synonym(S): 4-Amino-10-methylfolic acid hydrate, L-4-Amino-N10-methylpteroylglutamic acid hydrate, L-Amethopterin hydrate, Antifolan hydrate, MTX hydrate, Methylaminopterin hydrate
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 100 MG | M8407-100-MG | In Stock | ₹ 26,606.70 |
| 500 MG | M8407-500-MG | In Stock | ₹ 1,04,917.20 |
M8407 - 100 MG
In Stock
Quantity
1
Base Price: ₹ 26,606.70
GST (18%): ₹ 4,789.206
Total Price: ₹ 31,395.906
product line
BioReagent
Quality Level
200
Assay
≥98% (HPLC)
form
powder
technique(s)
cell culture | mammalian: suitable
solubility
H2O: insoluble
antibiotic activity spectrum
neoplasticsparasites
Mode of action
enzyme | inhibits
storage temp.
−20°C
SMILES string
[H]O[H].CN(Cc1cnc2nc(N)nc(N)c2n1)c3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O
Other Options
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Description
- Application: Methotrexate hydrate has been used: as a dihydrofolate (DHFR) inhibitor in sphere forming assay culture[1]as a component of dulbecco′ modified Eagle′s medium (DMEM) for selection of transfected cells[2][3] in viability and co-culture assays [4]
- Biochem/physiol Actions: Methotrexate is a folic acid antagonist.[5]
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
P202 - P264 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338
Hazard Classifications
Acute Tox. 3 Oral - Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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product line: BioReagent
Quality Level: 200
Assay: ≥98% (HPLC)
form: powder
technique(s): cell culture | mammalian: suitable
solubility: H2O: insoluble
antibiotic activity spectrum: neoplasticsparasites
Mode of action: enzyme | inhibits
storage temp.: −20°C
SMILES string: [H]O[H].CN(Cc1cnc2nc(N)nc(N)c2n1)c3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O
product line: __
Quality Level: 200
Assay: __
form: __
technique(s): electron microscopy: suitableimmunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:4,000 using protease-digested, sections of rabbit tongueindirect ELISA: suitableradioimmunoassay: suitablewestern blot: 1:5,000 using extract of rat or rabbit tongue
solubility: __
antibiotic activity spectrum: __
Mode of action: __
storage temp.: __
SMILES string: __
product line: __
Quality Level: 200
Assay: ≥96.0%
form: powder
technique(s): __
solubility: __
antibiotic activity spectrum: __
Mode of action: __
storage temp.: __
SMILES string: __