N0636

Nicotinamide

BioReagent, suitable for cell culture, suitable for insect cell culture

Manufacturer: Sigma Aldrich

CAS Number: 98-92-0

Synonym(S): Niacinamide, Nicotinic acid amide, Pyridine-3-carboxylic acid amide, Vitamin B3, Vitamin PP

Select a Size

Pack Size SKU Availability Price
100 G N0636-100-G In Stock ₹ 3,604.73
500 G N0636-500-G In Stock ₹ 10,153.85

N0636 - 100 G

₹ 3,604.73

In Stock

Quantity

1

Base Price: ₹ 3,604.73

GST (18%): ₹ 648.851

Total Price: ₹ 4,253.581

biological source

synthetic (organic)

Quality Level

200

product line

BioReagent

Assay

≥98% (HPLC)

form

powder

mol wt

Mw 122.12 g/mol

technique(s)

cell culture | insect: suitablecell culture | mammalian: suitable

color

white

mp

128-131 °C (lit.)

solubility

water: soluble 50 mg/mL, clear, colorless

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Description

  • General description: Nicotinamide (NAM) belongs to vitamin B family and is the amide form of vitamin B3. NAM is present in food and is a constituent of nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP). Tryptophan is the precursor for NAM synthesis in liver.[1] NAM controls cell metabolism, redox reactions, mitochondrial functionsand energy generation. It promotes natural killer cells proliferation and survival.[2] NAM confers neuroprotection and promotes neuronal maturation. It has the ability to cross the blood-brain barrier and may provide protection in ischaemic stroke and traumatic brain injury. NAM may elicit therapeutic benefits in Alzheimer′s, Parkinson′s, and Huntington′s diseases.[3]
  • Application: Nicotinamide has been used as a medium supplement in organoid culture of intestinal stem cells[4], esophageal squamous cell carcinomas(ESCC)[5], pancreatic cancer organoids[6] and pancreatic progenitor induction.[7]
  • Biochem/physiol Actions: Nicotinamide is an amide derivative of vitamin B3 and a PARP inhibitor

SAFETY INFORMATION

Pictograms

GHS07

Signal Word

Warning

Hazard Statements

H319

Precautionary Statements

P264 - P280 - P305 + P351 + P338 - P337 + P313

Hazard Classifications

Eye Irrit. 2

WGK

WGK 1

Flash Point(F)

closed cup

Flash Point(C)

closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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