P2076

Polymyxin B nonapeptide hydrochloride

lyopholized powder

Manufacturer: Sigma Aldrich

Synonym(S): PMBN

Select a Size

Pack Size SKU Availability Price
5 MG P2076-5-MG In Stock ₹ 17,016.90

P2076 - 5 MG

₹ 17,016.90

In Stock

Quantity

1

Base Price: ₹ 17,016.90

GST (18%): ₹ 3,063.042

Total Price: ₹ 20,079.942

Quality Level

200

form

lyophilized powder

color

white to light yellow

application(s)

cell analysis

storage temp.

2-8°C

SMILES string

CC(C)CC1NC(=O)C(Cc2ccccc2)NC(=O)C(CCN)NC(=O)C(CCNC(=O)C(NC(=O)C(CCN)NC(=O)C(CCN)NC1=O)C(C)O)NC(=O)C(CCN)NC(=O)C(N)C(C)O

InChI

1S/C43H74N14O11/c1-22(2)20-31-40(65)52-26(10-15-44)35(60)51-29(13-18-47)39(64)57-34(24(4)59)43(68)49-19-14-30(53-36(61)28(12-17-46)54-42(67)33(48)23(3)58)38(63)50-27(11-16-45)37(62)56-32(41(66)55-31)21-25-8-6-5-7-9-25/h5-9,22-24,26-34,58-59H,10-21,44-48H2,1-4H3,(H,49,68)(H,50,63)(H,51,60)(H,52,65)(H,53,61)(H,54,67)(H,55,66)(H,56,62)(H,57,64)

InChI key

PYHYGIPVYYRJHU-UHFFFAOYSA-N

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Description

  • Application: Polymyxin B nonapeptide hydrochloride has been used as an outer membrane permeabilizer, to characterize PAßN activity on membrane.[1] It has been used as a control in antibacterial assays.[2]
  • Biochem/physiol Actions: PMBN has endotoxin-neutralizing activity and thus can be utilized in adjunctive therapy against Gram-negative sepsis. It has been found that PMBN is less toxic than polymyxin B. Unlike polymyxin B, PMBN does not exhibit neurotoxicity and nephrotoxicity. While it retains the anti endotoxin property of the parent compound, it is much less potent.[3]

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Show Difference

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P2076

lyopholized powder...


Quality Level:
200

form:
lyophilized powder

color:
white to light yellow

application(s):
cell analysis

storage temp.:
2-8°C

SMILES string:
CC(C)CC1NC(=O)C(Cc2ccccc2)NC(=O)C(CCN)NC(=O)C(CCNC(=O)C(NC(=O)C(CCN)NC(=O)C(CCN)NC1=O)C(C)O)NC(=O)C(CCN)NC(=O)C(N)C(C)O

InChI:
1S/C43H74N14O11/c1-22(2)20-31-40(65)52-26(10-15-44)35(60)51-29(13-18-47)39(64)57-34(24(4)59)43(68)49-19-14-30(53-36(61)28(12-17-46)54-42(67)33(48)23(3)58)38(63)50-27(11-16-45)37(62)56-32(41(66)55-31)21-25-8-6-5-7-9-25/h5-9,22-24,26-34,58-59H,10-21,44-48H2,1-4H3,(H,49,68)(H,50,63)(H,51,60)(H,52,65)(H,53,61)(H,54,67)(H,55,66)(H,56,62)(H,57,64)

InChI key:
PYHYGIPVYYRJHU-UHFFFAOYSA-N

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JSPLKZUTYZBBKA-UHFFFAOYSA-N

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CCC(C(O)=O)c1ccccc1

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1S/C10H12O2/c1-2-9(10(11)12)8-6-4-3-5-7-8/h3-7,9H,2H2,1H3,(H,11,12)

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OFJWFSNDPCAWDK-UHFFFAOYSA-N

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SMILES string:
[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].C1CNCCN1

InChI:
__

InChI key:
__