P1004
Polymyxin B sulfate salt
Manufacturer: Sigma Aldrich
CAS Number: 1405-20-5
Synonym(S): Polymixin, Polymixin B, Polymixin B sulfate
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1000000 UNITS | P1004-1000000-UNITS | In Stock | ₹ 5,282.60 |
| 5000000 UNITS | P1004-5000000-UNITS | In Stock | ₹ 11,517.80 |
| 10000000 UNITS | P1004-10000000-UNITS | In Stock | ₹ 15,436.45 |
| 25000000 UNITS | P1004-25000000-UNITS | In Stock | ₹ 34,899.80 |
| 50000000 UNITS | P1004-50000000-UNITS | In Stock | ₹ 52,955.90 |
P1004 - 1000000 UNITS
In Stock
Quantity
1
Base Price: ₹ 5,282.60
GST (18%): ₹ 950.868
Total Price: ₹ 6,233.468
biological source
Pseudomonas aeruginosa
Quality Level
200
form
powder
storage condition
(Tightly closed. Dry. )
solubility
water: 50 mg/mL
antibiotic activity spectrum
Gram-negative bacteriafungi
Mode of action
cell membrane | interferes
storage temp.
2-8°C
SMILES string
O=C(C(NC(C(CCN)NC(CCCCC(C)CC)=O)=O)C(C)O)NC(CCN)C(NC(CCNC(C(NC(C(NC(C(CCN)N1)=O)CCN)=O)C(O)C)=O)C(NC(CCN)C(NC(CC2=CC=CC=C2)C(NC(CC(C)C)C1=O)=O)=O)=O)=O.O=S(O)(O)=O
InChI
1S/C48H82N16O13.H2O4S/c1-27(2)24-37-47(76)59-32(11-19-52)41(70)56-31(10-18-51)43(72)61-35(14-22-65)39(68)54-21-13-34(45(74)57-33(12-20-53)44(73)64-38(48(77)63-37)25-28-6-4-3-5-7-28)60-42(71)30(9-17-50)58-46(75)36(15-23-66)62-40(69)29(8-16-49)55-26-67;1-5(2,3)4/h3-7,26-27,29-38,65-66H,8-25,49-53H2,1-2H3,(H,54,68)(H,55,67)(H,56,70)(H,57,74)(H,58,75)(H,59,76)(H,60,71)(H,61,72)(H,62,69)(H,63,77)(H,64,73);(H2,1,2,3,4)
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | TOKU-E Polymyxin B ReadyMade™ Solution, 1405-20-5, 10 ML | TOKU-E | ₹ 13,261.80 | |
 | Polymyxin B Solution, 1 mg/mL in Water, MilliporeSigma™ Supelco™ | MilliporeSigma Supelco | ₹ 10,831.90 | |
 | U.S. Pharmacopeia Polymyxin B sulphate | 1405-20-5 | 1301.6 g/mol | 200MG | U.S. Pharmacopeia | ₹ 28,613.83 | |
| | Polymyxin B Sulfate Pharmaceutical Secondary Standard, MilliporeSigma™ Supelco™ | MilliporeSigma Supelco | ₹ 12,200.86 | |
| | Polymyxin B Sulfate, TCI America™ | TCI America | ₹ 13,321.69 | |
 | Sigma Aldrich Fine Chemicals Biosciences Polymyxin B sulfate United States Pharmacopeia (USP) Reference Standard | 1405-20-5 | 200MG | Sigma Aldrich Fine Chemicals Biosciences | ₹ 45,791.71 | |
 | TOKU-E Polymyxin B Sulfate, USP, 1405-20-5, 100 MU | TOKU-E | ₹ 41,496.60 | |
 | TOKU-E Polymyxin B Sulfate, USP, 1405-20-5, 10 MU | TOKU-E | ₹ 10,780.56 | |
| | Enzo Life Sciences Polymyxin B . sulfate (1g). CAS: 1405-20-5 | Enzo Life Sciences | ₹ 8,953.85 | |
 | Polymyxin B solution | Supelco | ₹ 8,086.28 |
Related Products
Description
- General description: Polymyxin B sulfate is a strongly cationic cyclic polypeptide antibiotic that is derived from fermentation of Bacilus polymyxa. It is a mixture of B1 and B2 sulfate.
- Application: Polymyxin B sulfate is a strongly cationic cyclic polypeptide antibiotic that is derived from fermentation of Bacilus polymyxa. It is a mixture of B1 and B2 sulfate. The product has been used clinically to treat infections of the urinary tract, meninges and blood stream caused by susceptible strains of Pseudomonas aeruginosa†. It also has uses studying multidrug-resistant pathogens††, as an immobilized agent for removal of endotoxins, and to induce pore formation in the membranes of cortex cells from excised sorghum roots.
- Biochem/physiol Actions: Polymyxin B is one of the most important antibiotics used to treat gram-negative bacterial infections, including infections caused by carbapenem-resistant non-fermenters and carbapenem-resistant Enterobacteriaceae[4].
- Features and Benefits: High quality antibiotic suitable for mulitple research applications
- Preparation Note: Polymyxin B sulfate is soluble in water at 50 mg/mL, producing a very slightly hazy, colorless to yellow solution. It has only minimal solubility in any organic solvent. For example, it has a solubility of 0.115 mg/mL in ethanol.Stock solutions should be sterile filtered and stored at 2-8°C. They are stable at 37°C for 5 days.
- Storage and Stability: As supplied, the product should be stored at 2-8°C in the dark. No change was observed in retained samples after three years′ of storage in these conditions.
- Other Notes: For additional information on our range of Biochemicals, please complete this form.
SAFETY INFORMATION
Pictograms
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Compare Similar Items
Show Difference
biological source: Pseudomonas aeruginosa
Quality Level: 200
form: powder
storage condition: (Tightly closed. Dry. )
solubility: water: 50 mg/mL
antibiotic activity spectrum: Gram-negative bacteriafungi
Mode of action: cell membrane | interferes
storage temp.: 2-8°C
SMILES string: O=C(C(NC(C(CCN)NC(CCCCC(C)CC)=O)=O)C(C)O)NC(CCN)C(NC(CCNC(C(NC(C(NC(C(CCN)N1)=O)CCN)=O)C(O)C)=O)C(NC(CCN)C(NC(CC2=CC=CC=C2)C(NC(CC(C)C)C1=O)=O)=O)=O)=O.O=S(O)(O)=O
InChI: 1S/C48H82N16O13.H2O4S/c1-27(2)24-37-47(76)59-32(11-19-52)41(70)56-31(10-18-51)43(72)61-35(14-22-65)39(68)54-21-13-34(45(74)57-33(12-20-53)44(73)64-38(48(77)63-37)25-28-6-4-3-5-7-28)60-42(71)30(9-17-50)58-46(75)36(15-23-66)62-40(69)29(8-16-49)55-26-67;1-5(2,3)4/h3-7,26-27,29-38,65-66H,8-25,49-53H2,1-2H3,(H,54,68)(H,55,67)(H,56,70)(H,57,74)(H,58,75)(H,59,76)(H,60,71)(H,61,72)(H,62,69)(H,63,77)(H,64,73);(H2,1,2,3,4)
biological source:
Pseudomonas aeruginosa
Quality Level:
200
form:
powder
storage condition:
(Tightly closed. Dry. )
solubility:
water: 50 mg/mL
antibiotic activity spectrum:
Gram-negative bacteriafungi
Mode of action:
cell membrane | interferes
storage temp.:
2-8°C
SMILES string:
O=C(C(NC(C(CCN)NC(CCCCC(C)CC)=O)=O)C(C)O)NC(CCN)C(NC(CCNC(C(NC(C(NC(C(CCN)N1)=O)CCN)=O)C(O)C)=O)C(NC(CCN)C(NC(CC2=CC=CC=C2)C(NC(CC(C)C)C1=O)=O)=O)=O)=O.O=S(O)(O)=O
InChI:
1S/C48H82N16O13.H2O4S/c1-27(2)24-37-47(76)59-32(11-19-52)41(70)56-31(10-18-51)43(72)61-35(14-22-65)39(68)54-21-13-34(45(74)57-33(12-20-53)44(73)64-38(48(77)63-37)25-28-6-4-3-5-7-28)60-42(71)30(9-17-50)58-46(75)36(15-23-66)62-40(69)29(8-16-49)55-26-67;1-5(2,3)4/h3-7,26-27,29-38,65-66H,8-25,49-53H2,1-2H3,(H,54,68)(H,55,67)(H,56,70)(H,57,74)(H,58,75)(H,59,76)(H,60,71)(H,61,72)(H,62,69)(H,63,77)(H,64,73);(H2,1,2,3,4)
biological source: __
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solubility: __
antibiotic activity spectrum: __
Mode of action: __
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SMILES string: __
InChI: __
biological source:
__
Quality Level:
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form:
__
storage condition:
__
solubility:
__
antibiotic activity spectrum:
__
Mode of action:
__
storage temp.:
__
SMILES string:
__
InChI:
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biological source: __
Quality Level: 300
form: powder or solid
storage condition: __
solubility: __
antibiotic activity spectrum: __
Mode of action: __
storage temp.: −20°C
SMILES string: O=C(C)[C@@](NC)([H])CCCCN.[Br]
InChI: 1S/C6H14N2O2.BrH/c7-4-2-1-3-5(8)6(9)10;/h5H,1-4,7-8H2,(H,9,10);1H
biological source:
__
Quality Level:
300
form:
powder or solid
storage condition:
__
solubility:
__
antibiotic activity spectrum:
__
Mode of action:
__
storage temp.:
−20°C
SMILES string:
O=C(C)[C@@](NC)([H])CCCCN.[Br]
InChI:
1S/C6H14N2O2.BrH/c7-4-2-1-3-5(8)6(9)10;/h5H,1-4,7-8H2,(H,9,10);1H
biological source: __
Quality Level: 300
form: powder or solid
storage condition: __
solubility: __
antibiotic activity spectrum: __
Mode of action: __
storage temp.: −20°C
SMILES string: O=C(C)[C@@](NC)([H])CCCCN.[Br]
InChI: 1S/C6H14N2O2.BrH/c7-4-2-1-3-5(8)6(9)10;/h5H,1-4,7-8H2,(H,9,10);1H
biological source:
__
Quality Level:
300
form:
powder or solid
storage condition:
__
solubility:
__
antibiotic activity spectrum:
__
Mode of action:
__
storage temp.:
−20°C
SMILES string:
O=C(C)[C@@](NC)([H])CCCCN.[Br]
InChI:
1S/C6H14N2O2.BrH/c7-4-2-1-3-5(8)6(9)10;/h5H,1-4,7-8H2,(H,9,10);1H