D2446

Daptomycin

cyclic lipopeptide antibiotic

Manufacturer: Sigma Aldrich

CAS Number: 103060-53-3

Synonym(S): Cubicin, Daptomycin, 9-L beta-Aspartic Acid, Dapcin

Select a Size

Pack Size SKU Availability Price
1 MG D2446-1-MG In Stock ₹ 43,126.80

D2446 - 1 MG

₹ 43,126.80

In Stock

Quantity

1

Base Price: ₹ 43,126.80

GST (18%): ₹ 7,762.824

Total Price: ₹ 50,889.624

Quality Level

100

Assay

≥90% (HPLC)

form

powder

solubility

methanol: 5 mg/mLDMSO: solubleethanol: solublemethanol: soluble

antibiotic activity spectrum

Gram-positive bacteria

Mode of action

DNA synthesis | interferesprotein synthesis | interferes

storage temp.

−20°C

SMILES string

CCCCCCCCCC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](CC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@H]3[C@@H](C)OC(=O)[C@H](CC(=O)c4ccccc4N)NC(=O)[C@@H](NC(=O)[C@@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](CCCN)NC(=O)CNC3=O)[C@H](C)CC(O)=O

InChI

1S/C72H101N17O26/c1-5-6-7-8-9-10-11-22-53(93)81-44(25-38-31-76-42-20-15-13-17-39(38)42)66(108)84-45(27-52(75)92)67(109)86-48(30-59(102)103)68(110)89-61-37(4)115-72(114)49(26-51(91)40-18-12-14-19-41(40)74)87-71(113)60(35(2)24-56(96)97)88-69(111)50(34-90)82-55(95)32-77-63(105)46(28-57(98)99)83-62(104)36(3)79-65(107)47(29-58(100)101)85-64(106)43(21-16-23-73)80-54(94)33-78-70(61)112/h12-15,17-20,31,35-37,43-50,60-61,76,90H,5-11,16,21-30,32-34,73-74H2,1-4H3,(H2,75,92)(H,77,105)(H,78,112)(H,79,107)(H,80,94)(H,81,93)(H,82,95)(H,83,104)(H,84,108)(H,85,106)(H,86,109)(H,87,113)(H,88,111)(H,89,110)(H,96,97)(H,98,99)(H,100,101)(H,102,103)/t35-,36-,37-,43-,44+,45-,46+,47+,48+,49+,50-,60+,61+/m1/s1

InChI key

DOAKLVKFURWEDJ-FAZHXZQASA-N

Other Options

Image Product Name Manufacturer Price Range
50-101-3142
Apexbio Technology LLC Calcium-dependent antibiotic. 103060-53-3. MFCD08282794
Apexbio Technology LLC ₹ 4,534.68
50-173-7406
Sigma Aldrich Fine Chemicals Biosciences Daptomycin Ready Made Solution 1 mg/mL in DMSO | 103060-53-3 | MFCD28968054 | 0.5ML
Sigma Aldrich Fine Chemicals Biosciences ₹ 24,421.39
50-245-6917
eMolecules​ AstaTech / DAPTOMYCIN / 0.1g / 268495124 / 41041 / 98.000 / 103060-53-3 / [null] / 1620.693 / C72H101N17O26
eMolecules​ ₹ 9,571.60
50-136-1188
Selleck Chemical LLC Daptomycin 20mg 103060-53-3 LY146032
Selleck Chemical LLC ₹ 15,092.78
50-766-6
Selleck Chemical LLC Daptomycin 100mg 103060-53-3 LY146032
Selleck Chemical LLC ₹ 37,988.64
SBR00014
Daptomycin Ready Made Solution
Sigma Aldrich ₹ 20,675.75
D2446
Daptomycin
Sigma Aldrich ₹ 43,126.80
SBR00014
Daptomycin Ready Made Solution
Sigma Aldrich ₹ 20,675.75
CS-1857
Daptomycin
ChemScene ₹ 5,903.64 - ₹ 21,304.44

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Description

  • Application: Daptomycin has been studied as a potential therapy for Streptococcus pneumoniae infections.[1] It has also been used to study the impact of sarA on daptomycin susceptibility of Staphylococcus aureus.[2]
  • Biochem/physiol Actions: Daptomycin is a cyclic lipopeptide antibiotic. isolated from Streptomyces sp. It is effective against Gram-positive bacteria. It disrupts the plasma membrane causes rapid depolarization and inhibits the synthesis of protein, RNA and DNA. It is potent against Staphylococcus aureus infections, including MRSA (methicillin-resistant Staphylococcus aureus).
  • Other Notes: Keep container tightly closed in a dry and well-ventilated place.

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Compare Similar Items

Show Difference

Img

Sigma Aldrich

D2446

cyclic lipopeptide antibiotic...


Quality Level:
100

Assay:
≥90% (HPLC)

form:
powder

solubility:
methanol: 5 mg/mLDMSO: solubleethanol: solublemethanol: soluble

antibiotic activity spectrum:
Gram-positive bacteria

Mode of action:
DNA synthesis | interferesprotein synthesis | interferes

storage temp.:
−20°C

SMILES string:
CCCCCCCCCC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](CC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@H]3[C@@H](C)OC(=O)[C@H](CC(=O)c4ccccc4N)NC(=O)[C@@H](NC(=O)[C@@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](CCCN)NC(=O)CNC3=O)[C@H](C)CC(O)=O

InChI:
1S/C72H101N17O26/c1-5-6-7-8-9-10-11-22-53(93)81-44(25-38-31-76-42-20-15-13-17-39(38)42)66(108)84-45(27-52(75)92)67(109)86-48(30-59(102)103)68(110)89-61-37(4)115-72(114)49(26-51(91)40-18-12-14-19-41(40)74)87-71(113)60(35(2)24-56(96)97)88-69(111)50(34-90)82-55(95)32-77-63(105)46(28-57(98)99)83-62(104)36(3)79-65(107)47(29-58(100)101)85-64(106)43(21-16-23-73)80-54(94)33-78-70(61)112/h12-15,17-20,31,35-37,43-50,60-61,76,90H,5-11,16,21-30,32-34,73-74H2,1-4H3,(H2,75,92)(H,77,105)(H,78,112)(H,79,107)(H,80,94)(H,81,93)(H,82,95)(H,83,104)(H,84,108)(H,85,106)(H,86,109)(H,87,113)(H,88,111)(H,89,110)(H,96,97)(H,98,99)(H,100,101)(H,102,103)/t35-,36-,37-,43-,44+,45-,46+,47+,48+,49+,50-,60+,61+/m1/s1

InChI key:
DOAKLVKFURWEDJ-FAZHXZQASA-N

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Sigma Aldrich

D2447

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200

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antibiotic activity spectrum:
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Mode of action:
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__

InChI:
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InChI key:
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Invitrogen™

D250

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SMILES string:
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InChI:
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InChI key:
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