P7136

Pyrazinecarboxamide

Manufacturer: Sigma Aldrich

CAS Number: 98-96-4

Synonym(S): Pyrazinamide, Pyrazinoic acid amide

Select a Size

Pack Size SKU Availability Price
10 G P7136-10-G In Stock ₹ 6,670.00
25 G P7136-25-G In Stock ₹ 9,510.00
100 G P7136-100-G In Stock ₹ 19,333.45

P7136 - 10 G

₹ 6,670.00

In Stock

Quantity

1

Base Price: ₹ 6,670.00

GST (18%): ₹ 1,200.60

Total Price: ₹ 7,870.60

form

powder

Quality Level

200

mp

189-191 °C (lit.)

antibiotic activity spectrum

mycobacteria

Mode of action

cell membrane | interferes

SMILES string

NC(=O)c1cnccn1

InChI

1S/C5H5N3O/c6-5(9)4-3-7-1-2-8-4/h1-3H,(H2,6,9)

InChI key

IPEHBUMCGVEMRF-UHFFFAOYSA-N

Other Options

Image Product Name Manufacturer Price Range
11-101-6013
Pyrazinamide, Pharmaceutical Secondary Standard, Certified Reference Material, MilliporeSigma™ Supelco™
MilliporeSigma Supelco ₹ 23,529.00
50-224-0527
Apexbio Technology LLC Pyrazinamide,10g CAS# 98-96-4
Apexbio Technology LLC ₹ 4,534.68
PHR1576
Pyrazinamide
Supelco ₹ 21,509.28
1585006
Pyrazinamide
Sigma Aldrich ₹ 40,756.13
P4050000
Pyrazinamide
Sigma Aldrich ₹ 14,267.35
BP906
Pyrazinamide
Sigma Aldrich ₹ 20,892.25
P7136
Pyrazinecarboxamide
Sigma Aldrich ₹ 6,670.00 - ₹ 19,333.45
CS-2260
Pyrazinamide
ChemScene ₹ 1,197.84 - ₹ 16,513.08

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Description

  • Application: Pyrazinamide is used therapeutically as an antitubercular agent. Pyrazinamide is used to form polymeric copper complexes, create pyrazine carboxamide scaffolds useful as FXs inhibitors, and as a component of mycobacteria identification kits. It is used to study liver toxicity prevention [1] and mechanisms of resistance [2].
  • Biochem/physiol Actions: The active moiety of pyrazinamide is pyrazinoic acid (POA). POA is thought to disrupt membrane energetics and inhibit membrane transport function at acid pH in Mycobacterium tuberculosis. Iron enhances the antituberculous activity of pyrazinamide [3]. Pyrazinamide and its analogs have been shown to inhibit the activity of purified FAS I.
  • Other Notes: Keep container tightly closed in a dry and well-ventilated place.

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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mycobacteria

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cell membrane | interferes

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NC(=O)c1cnccn1

InChI:
1S/C5H5N3O/c6-5(9)4-3-7-1-2-8-4/h1-3H,(H2,6,9)

InChI key:
IPEHBUMCGVEMRF-UHFFFAOYSA-N

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