SRP3059
Interferon-λ human
recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture
Manufacturer: Sigma Aldrich
Synonym(S): IFN-λ human, IL-29
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 20 μG | SRP3059-20-μG | In Stock | ₹ 35,830.80 |
SRP3059 - 20 μG
In Stock
Quantity
1
Base Price: ₹ 35,830.80
GST (18%): ₹ 6,449.544
Total Price: ₹ 42,280.344
biological source
human
recombinant
expressed in E. coli
Assay
≥98% (HPLC)≥98% (SDS-PAGE)
form
lyophilized
potency
0.2-0.5 ng/mL ED50
mol wt
19.8 kDa
packaging
pkg of 20 μg
technique(s)
cell culture | mammalian: suitable
impurities
<0.1 EU/μg endotoxin, tested
color
white to off-white
Related Products
Description
- General description: IFN-λ-1,-2, and -3 (also known as IL-29, IL-28A and IL-28B respectively) are distantly related to the IL-10 family of interferons. All three IFN-λs use a distinct receptor system composed of an IFN-λR1 subunit (also called CRF2-12) and IL-10R2 subunit (also called CRF2-14). Signaling through this receptor system induces antiviral defense similar but distinct than the type I Interferons.[1] Recombinant human IFN-L1 is a 19.8kDa protein containing 178 amino acid residues.
- Biochem/physiol Actions: Interleukin-29 (IL-29) enhances the production of interleukins from monocytes. It has been observed that it stimulates antiviral responses to herpes simplex virus 1 in vitro. Serums from patients with rheumatoid arthritis have high levels of IL29.[2][3][4]
- Sequence: PTSKPTTTGK GCHIGRFKSL SPQELASFKK ARDALEESLK LKNWSCSSPV FPGNWDLRLL QVRERPVALE AELALTLKVL EAAAGPALED VLDQPLHTLH HILSQLQACI QPQPTAGPRP RGRLHHWLHR LQEAPKKESA GCLEASVTFN LFRLLTRDLK YVADGNLCLR TSTHPEST
- Physical form: Lyophilized from 1x PBS.
- Reconstitution: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.5-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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biological source: human
recombinant: expressed in E. coli
Assay: ≥98% (HPLC)≥98% (SDS-PAGE)
form: lyophilized
potency: 0.2-0.5 ng/mL ED50
mol wt: 19.8 kDa
packaging: pkg of 20 μg
technique(s): cell culture | mammalian: suitable
impurities: <0.1 EU/μg endotoxin, tested
color: white to off-white
biological source:
human
recombinant:
expressed in E. coli
Assay:
≥98% (HPLC)≥98% (SDS-PAGE)
form:
lyophilized
potency:
0.2-0.5 ng/mL ED50
mol wt:
19.8 kDa
packaging:
pkg of 20 μg
technique(s):
cell culture | mammalian: suitable
impurities:
<0.1 EU/μg endotoxin, tested
color:
white to off-white
biological source: human
recombinant: expressed in E. coli
Assay: ≥98% (HPLC)≥98% (SDS-PAGE)
form: lyophilized
potency: __
mol wt: 19.6 kDa
packaging: pkg of 20 μg
technique(s): cell culture | mammalian: suitable
impurities: <0.1 EU/μg endotoxin, tested
color: white to off-white
biological source:
human
recombinant:
expressed in E. coli
Assay:
≥98% (HPLC)≥98% (SDS-PAGE)
form:
lyophilized
potency:
__
mol wt:
19.6 kDa
packaging:
pkg of 20 μg
technique(s):
cell culture | mammalian: suitable
impurities:
<0.1 EU/μg endotoxin, tested
color:
white to off-white
biological source: human
recombinant: expressed in E. coli
Assay: ≥98% (HPLC)≥98% (SDS-PAGE)
form: lyophilized
potency: ≤0.01 ng/mL ED50
mol wt: 19.9 kDa
packaging: pkg of 100 μg
technique(s): cell culture | mammalian: suitable
impurities: <0.1 EU/μg endotoxin, tested
color: white to off-white
biological source:
human
recombinant:
expressed in E. coli
Assay:
≥98% (HPLC)≥98% (SDS-PAGE)
form:
lyophilized
potency:
≤0.01 ng/mL ED50
mol wt:
19.9 kDa
packaging:
pkg of 100 μg
technique(s):
cell culture | mammalian: suitable
impurities:
<0.1 EU/μg endotoxin, tested
color:
white to off-white
biological source: human
recombinant: expressed in E. coli
Assay: ≥95% (HPLC)
form: lyophilized powder
potency: 0.1-10 ng/mL ED50/EC50
mol wt: ~7.6 kDa
packaging: pkg of 100 μgpkg of 50 μg
technique(s): cell culture | mammalian: suitable
impurities: ≤1.00 EU/μg endotoxin, tested
color: __
biological source:
human
recombinant:
expressed in E. coli
Assay:
≥95% (HPLC)
form:
lyophilized powder
potency:
0.1-10 ng/mL ED50/EC50
mol wt:
~7.6 kDa
packaging:
pkg of 100 μgpkg of 50 μg
technique(s):
cell culture | mammalian: suitable
impurities:
≤1.00 EU/μg endotoxin, tested
color:
__