CT-2A-Luc Mouse Glioma Cell Line

Description

• General description: Glioblastomas are among the most aggressive forms of cancer, associated with low treatment efficacy and poor survival. Recurring glioblastomas are often resistant to first-line chemotherapies (1). There is much interest in studying drug-resistant forms of glioblastomas in the effort to develop effective therapies. References:1. Weller M, Cloughesy T, Perry JR, and Wick W (2013) Neuro Oncol 15(1): 4-27.2. Seyfried TN, Mukherjee P (2010) J Oncol 2010:961243 doi.10.1155/2010/961243.3. Cotterchio M, Seyfried TN (1994) J Lipid Res 35(1): 10-14. 4. Binello E, Qadeer ZA, Kothari HP, Emdad L, Germano IM (2012) J Cancer 3: 166-174.5. Martinez-Murillo R, Martinez A (2007) Histol Histopathol 22(12): 1309-1326.6. Zimmerman HM and Arnold H. (1941) Cancer Res 1(12): 919-938.7. Huysentruyt LC, Mukherjee P, Banerjee D, Shelton LM, Seyfried TN (2008) Int J Cancer 123(1): 73-84.
• Cell Line Description: Cancer Cells
• Application: Research CategoryCancerOncology
• Quality: • Each vial contains 1X10⁶ viable cells.• Cells are tested negative for infectious diseases by a Mouse Essential CLEAR panel by Charles River Animal Diagnostic Services.• Cells are verified to be of mouse origin and negative for inter-species contamination from rat, chinese hamster, Golden Syrian hamster, human and non-human primate (NHP) as assessed by a Contamination CLEAR panel by Charles River Animal Diagnostic Services.• Cells are negative for mycoplasma contamination
• Storage and Stability: Store in liquid nitrogen. The cells can be cultured for at least 10 passages after initial thawing without significantly affecting the cell marker expression and functionality.