NovaSyn®TG amino resin (90 µm)

Description

• General description: NovaSyn TG resin is a composite of polyethylene glycol and a low-crosslinked polystyrene gel-type resin [1,2,3]. The 90 μm beads have a narrow size distribution, excellent pressure stability and swelling properties, and high diffusion rates, making them ideally suited for both batch or continuous flow peptide synthesis. Functionalized with an amino group, the resin can be readily derivatized with any carboxylic acid-containing linker using standard methods of amide bond formation. Furthermore, the excellent swelling properties in water of this support make it well suited to the preparation of peptide libraries.Associated Protocols and Technical ArticlesProtocols for Loading of Peptide Synthesis ResinsLiterature references [1] W. Rapp, et al. in ′Innovation & Perspectives in Solid Phase Synthesis, 1st International Symposium′, R. Epton (Eds), SPCC UK Ltd., Birmingham, 1990, pp. 205.[2] L. Zhang, et al. in ′Peptides 1990, Proc. 21st European Peptide Symposium′, E. Giralt & D. Andreu (Eds), ESCOM, Leiden, 1990, pp.196.[3] E. Bayer (1991) Angew. Chem. Int. Ed. Engl., 30, 113.
• Linkage: Replaces: 01-64-0043
• Analysis Note: Color (visual): white to yellow to beigeAppearance of substance (visual): beadsLoading (determined from the substitution of the Fmoc-Leu loaded resin): 0.20 - 0.30 mmol/gSwelling Volume (in CH₂Cl₂): lot specific resultThe base resin ist PEG-PS copolymer (90µm), functionalised with an amino group.
• Legal Information: NOVASYN is a registered trademark of Merck KGaA, Darmstadt, Germany