Fmoc-Asp(OtBu)-Wang resin (100-200 mesh)

Description

• General description: Pre-loaded resin for synthesis of peptide acids containing a C-terminal aspartic acid amino-acid residue by Fmoc SPPS. This pre-loaded Wang resin is prepared using a synthesis-tested base resin, to ensure reproducibility and efficacy in SPPS. Loading of the Fmoc-amino acid is carried out under conditions to minimize enantiomerization and dipeptide formation, the values of which are provided on the COA. The lot number of the batch of Fmoc-amino acid used to prepare the resin is also provided on the COA, to provide transparency and traceability. Associated Protocols and Technical Articles Cleavage and Deprotection Protocols for Fmoc SPPS
• Linkage: Replaces: 04-12-2047
• Analysis Note: Color (visual): white to yellow to beigeAppearance of substance (visual): beadsLoading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0.40 - 1.00 mmol/gEnantiomeric purity: ≥ 99.5 % (a/a)Swelling Volume (in DMF): lot specific resultIdentity (of the substitution): passes testContent Dipeptide (HPLC): ≤ 0.50 % (a/a)Novabiochem Fmoc amino acid: lot numberThe qualitiy of this resin has been confirmed by the successful synthesis of the 21mer peptide related to myelin oligodendrocyte glycoprotein (35-55), with an Fmoc-Val-Wang resin made from the same batch of base resin.The polymer matrix is copoly (styrene-1 % DVB), 100 - 200 mesh.
• Legal Information: Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany