Description

• General description: Quercetin 3-β-D-glucoside (Q3G), also known as isoquercitrin, is one of the major glycosidic forms of quercetin.[1] It is a mono-glucoside, first isolated from the seed pods of Cercis canadensis L., it is also found in various plants, vegetables, and fruits.[1] Q3G has the basic chemical structure of a flavonoid, with a glucose molecule attached to the C-3 of quercetin.[1]
• Application: Quercetin 3-β-D-glucoside has been used:as a dietary flavonoid supplement to check its binding capacity with human small ubiquitin-related modifier 1 (SUMO1) protein using surface plasmon resonance (SPR)[2]as an inhibitor for Escherichia coli adenosine triphosphate (ATP) synthase[3]as an anti-aggregation agent to test its activity against β-amyloid, green fluorescent protein (GFP), and chymotrypsinogen proteins[4]
• Biochem/physiol Actions: Quercetin 3-β-D-glucoside possesses strong antioxidant and anti-inflammatory activities.[1] Being a potent oxygen-radical scavenger, it is a neuroprotective agent that improves Alzheimer′s disease (AD) condition in mice models.[5] It has shown antiproliferative activity against colon, lung, and hepatocellular cell lines[6] and MCF-7 human breast cancer cells in combination with apple extracts.[7]
• Packaging: Bottomless glass bottle. Contents are inside inserted fused cone.