17936
1α,25-Dihydroxyvitamin D3
≥97.0% (HPLC)
Manufacturer: Sigma Aldrich
CAS Number: 32222-06-3
Synonym(S): 1α,25-Dihydroxycholecalciferol, Calcitriol
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 100 μG | 17936-100-μG | In Stock | ₹ 51,830.10 |
| 1 MG | 17936-1-MG | In Stock | ₹ 1,27,583.45 |
17936 - 100 μG
In Stock
Quantity
1
Base Price: ₹ 51,830.10
GST (18%): ₹ 9,329.418
Total Price: ₹ 61,159.518
Quality Level
200
Assay
≥97.0% (HPLC)
form
crystals
color
white to off-white
storage temp.
−70°C
SMILES string
[H][C@@]1(CC[C@@]2([H])C(\CCC[C@]12C)=C\C=C3\C[C@@H](O)C[C@H](O)C3=C)[C@H](C)CCCC(C)(C)O
InChI
1S/C27H44O3/c1-18(8-6-14-26(3,4)30)23-12-13-24-20(9-7-15-27(23,24)5)10-11-21-16-22(28)17-25(29)19(21)2/h10-11,18,22-25,28-30H,2,6-9,12-17H2,1,3-5H3/b20-10+,21-11-/t18-,22-,23-,24+,25+,27-/m1/s1
InChI key
GMRQFYUYWCNGIN-NKMMMXOESA-N
Gene Information
human ... VDR(7421)
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Medchemexpress LLC HY-10002 10mg , Calcitriol CAS:32222-06-3 Purity:>98% | Medchemexpress LLC | ₹ 21,561.12 | |
 | Apexbio Technology LLC Calcitriol, 25mg. Cas: 32222-06-3 MFCD: MFCD00867079. Active metabolite of vitamin D3 | Apexbio Technology LLC | ₹ 48,512.52 | |
| | Apexbio Technology LLC Calcitriol, 1mg. Cas: 32222-06-3 MFCD: MFCD00867079. Active metabolite of vitamin D3 | Apexbio Technology LLC | ₹ 5,475.84 | |
 | Sigma Aldrich Fine Chemicals Biosciences Calcitriol solution United States Pharmacopeia (USP) Reference Standard | 32222-06-3 | 5ML | Sigma Aldrich Fine Chemicals Biosciences | ₹ 60,063.12 | |
 | Enzo Life Sciences 1alpha,25-Dihydroxyvitamin D3 (1mg). CAS: 32222-06-3 | Enzo Life Sciences | ₹ 2,29,441.12 | |
 | 1α,25-Dihydroxyvitamin D3 solution | Supelco | ₹ 25,059.88 | |
| | Calcitriol | Supelco | ₹ 81,176.68 | |
 | Calcitriol | Sigma Aldrich | ₹ 1,80,376.98 | |
| | Calcitriol solution | Sigma Aldrich | ₹ 53,399.73 | |
| | 1α,25-Dihydroxyvitamin D3 | Sigma Aldrich | ₹ 23,576.85 - ₹ 83,352.50 |
Description
- General description: 1α,25-Dihydroxyvitamin D3, also referred as calcitriol, is a calcitrophic hormone.[1] It is the most biologically active metabolite of vitamin D produced in proximal tubular cells in the kidney.[2][3]
- Application: 1α,25-Dihydroxyvitamin D3 has been used to study its effect on transplantation success of human muscle precursor cells (hMPCs) in severe combined immunodeficient (SCID) mice in-vitro.[4]
- Biochem/physiol Actions: 1α,25-Dihydroxyvitamin D3 modulates energy metabolism by facilitating various metabolic processes, such as Ca2+ signaling and modulation of glucocorticoids, by affecting adipocyte apoptosis and by regulating the expression and production of multiple cytokines.[1] In addition, it also modulates phosphorus homeostasis through actions in the intestine, kidney and bone.[5] 1α,25-Dihydroxyvitamin D3 exhibits antiproliferative effects and is used as a potent therapeutic for human prostate cancer.[6]
- Packaging: Bottomless glass bottle. Contents are inside inserted fused cone.
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
P260 - P262 - P280 - P302 + P352 + P310 - P304 + P340 + P310 - P314
Hazard Classifications
Acute Tox. 1 Oral - Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - STOT RE 1
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Compare Similar Items
Show Difference
Quality Level: 200
Assay: ≥97.0% (HPLC)
form: crystals
color: white to off-white
storage temp.: −70°C
SMILES string: [H][C@@]1(CC[C@@]2([H])C(\CCC[C@]12C)=C\C=C3\C[C@@H](O)C[C@H](O)C3=C)[C@H](C)CCCC(C)(C)O
InChI: 1S/C27H44O3/c1-18(8-6-14-26(3,4)30)23-12-13-24-20(9-7-15-27(23,24)5)10-11-21-16-22(28)17-25(29)19(21)2/h10-11,18,22-25,28-30H,2,6-9,12-17H2,1,3-5H3/b20-10+,21-11-/t18-,22-,23-,24+,25+,27-/m1/s1
InChI key: GMRQFYUYWCNGIN-NKMMMXOESA-N
Gene Information: human ... VDR(7421)
Quality Level:
200
Assay:
≥97.0% (HPLC)
form:
crystals
color:
white to off-white
storage temp.:
−70°C
SMILES string:
[H][C@@]1(CC[C@@]2([H])C(\CCC[C@]12C)=C\C=C3\C[C@@H](O)C[C@H](O)C3=C)[C@H](C)CCCC(C)(C)O
InChI:
1S/C27H44O3/c1-18(8-6-14-26(3,4)30)23-12-13-24-20(9-7-15-27(23,24)5)10-11-21-16-22(28)17-25(29)19(21)2/h10-11,18,22-25,28-30H,2,6-9,12-17H2,1,3-5H3/b20-10+,21-11-/t18-,22-,23-,24+,25+,27-/m1/s1
InChI key:
GMRQFYUYWCNGIN-NKMMMXOESA-N
Gene Information:
human ... VDR(7421)
Quality Level: 200
Assay: ≥95.0% (HPLC)
form: crystals
color: white to colorless
storage temp.: −70°C
SMILES string: [H][C@@]12CC[C@H]([C@H](C)\C=C\[C@H](C)C(C)(C)O)[C@@]1(C)CCC/C2=C\C=C3\C[C@@H](O)CCC3=C
InChI: 1S/C28H44O2/c1-19-10-14-24(29)18-23(19)13-12-22-8-7-17-28(6)25(15-16-26(22)28)20(2)9-11-21(3)27(4,5)30/h9,11-13,20-21,24-26,29-30H,1,7-8,10,14-18H2,2-6H3/b11-9+,22-12+,23-13-/t20-,21+,24+,25-,26+,28-/m1/s1
InChI key: KJKIIUAXZGLUND-ICCVIKJNSA-N
Gene Information: __
Quality Level:
200
Assay:
≥95.0% (HPLC)
form:
crystals
color:
white to colorless
storage temp.:
−70°C
SMILES string:
[H][C@@]12CC[C@H]([C@H](C)\C=C\[C@H](C)C(C)(C)O)[C@@]1(C)CCC/C2=C\C=C3\C[C@@H](O)CCC3=C
InChI:
1S/C28H44O2/c1-19-10-14-24(29)18-23(19)13-12-22-8-7-17-28(6)25(15-16-26(22)28)20(2)9-11-21(3)27(4,5)30/h9,11-13,20-21,24-26,29-30H,1,7-8,10,14-18H2,2-6H3/b11-9+,22-12+,23-13-/t20-,21+,24+,25-,26+,28-/m1/s1
InChI key:
KJKIIUAXZGLUND-ICCVIKJNSA-N
Gene Information:
__
Quality Level: 200
Assay: ≥99.0% (HPLC)
form: powder or crystals
color: white to off-white
storage temp.: −20°C
SMILES string: [H][C@@]1(CC[C@@]2([H])C(\CCC[C@]12C)=C\C=C3\C[C@@H](O)CCC3=C)[C@H](C)CCCC(C)(C)O
InChI: 1S/C27H44O2/c1-19-10-13-23(28)18-22(19)12-11-21-9-7-17-27(5)24(14-15-25(21)27)20(2)8-6-16-26(3,4)29/h11-12,20,23-25,28-29H,1,6-10,13-18H2,2-5H3/b21-11+,22-12-/t20-,23+,24-,25+,27-/m1/s1
InChI key: JWUBBDSIWDLEOM-DTOXIADCSA-N
Gene Information: __
Quality Level:
200
Assay:
≥99.0% (HPLC)
form:
powder or crystals
color:
white to off-white
storage temp.:
−20°C
SMILES string:
[H][C@@]1(CC[C@@]2([H])C(\CCC[C@]12C)=C\C=C3\C[C@@H](O)CCC3=C)[C@H](C)CCCC(C)(C)O
InChI:
1S/C27H44O2/c1-19-10-13-23(28)18-22(19)12-11-21-9-7-17-27(5)24(14-15-25(21)27)20(2)8-6-16-26(3,4)29/h11-12,20,23-25,28-29H,1,6-10,13-18H2,2-5H3/b21-11+,22-12-/t20-,23+,24-,25+,27-/m1/s1
InChI key:
JWUBBDSIWDLEOM-DTOXIADCSA-N
Gene Information:
__
Quality Level: 200
Assay: ≥99.0% (HPLC)
form: powder or crystals
color: white to off-white
storage temp.: −20°C
SMILES string: [H][C@@]1(CC[C@@]2([H])C(\CCC[C@]12C)=C\C=C3\C[C@@H](O)CCC3=C)[C@H](C)CCCC(C)(C)O
InChI: 1S/C27H44O2/c1-19-10-13-23(28)18-22(19)12-11-21-9-7-17-27(5)24(14-15-25(21)27)20(2)8-6-16-26(3,4)29/h11-12,20,23-25,28-29H,1,6-10,13-18H2,2-5H3/b21-11+,22-12-/t20-,23+,24-,25+,27-/m1/s1
InChI key: JWUBBDSIWDLEOM-DTOXIADCSA-N
Gene Information: __
Quality Level:
200
Assay:
≥99.0% (HPLC)
form:
powder or crystals
color:
white to off-white
storage temp.:
−20°C
SMILES string:
[H][C@@]1(CC[C@@]2([H])C(\CCC[C@]12C)=C\C=C3\C[C@@H](O)CCC3=C)[C@H](C)CCCC(C)(C)O
InChI:
1S/C27H44O2/c1-19-10-13-23(28)18-22(19)12-11-21-9-7-17-27(5)24(14-15-25(21)27)20(2)8-6-16-26(3,4)29/h11-12,20,23-25,28-29H,1,6-10,13-18H2,2-5H3/b21-11+,22-12-/t20-,23+,24-,25+,27-/m1/s1
InChI key:
JWUBBDSIWDLEOM-DTOXIADCSA-N
Gene Information:
__