17946

1α-Hydroxyvitamin D3

≥97.0% (HPLC)

Manufacturer: Sigma Aldrich

CAS Number: 41294-56-8

Synonym(S): 1α-Hydroxycholecalciferol, Alfacalcidol

Select a Size

Pack Size SKU Availability Price
1 MG 17946-1-MG In Stock ₹ 30,483.20

17946 - 1 MG

₹ 30,483.20

In Stock

Quantity

1

Base Price: ₹ 30,483.20

GST (18%): ₹ 5,486.976

Total Price: ₹ 35,970.176

biological source

synthetic

Quality Level

200

Assay

≥97.0% (HPLC)

form

powder or crystals

color

white to off-white

storage temp.

−20°C

SMILES string

CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C3\C[C@@H](O)C[C@H](O)C3=C

InChI

1S/C27H44O2/c1-18(2)8-6-9-19(3)24-13-14-25-21(10-7-15-27(24,25)5)11-12-22-16-23(28)17-26(29)20(22)4/h11-12,18-19,23-26,28-29H,4,6-10,13-17H2,1-3,5H3/b21-11+,22-12-/t19-,23-,24-,25+,26+,27-/m1/s1

InChI key

OFHCOWSQAMBJIW-AVJTYSNKSA-N

Gene Information

human ... VDR(7421)

Other Options

Image Product Name Manufacturer Price Range
50-193-1701
Medchemexpress LLC HY-10003 5mg Medchemexpress, Alfacalcidol CAS:41294-56-8 Purity:>98%
Medchemexpress LLC ₹ 7,905.74
Y0002125
Alfacalcidol for system suitability A
Sigma Aldrich ₹ 13,856.00
A0325450
Alfacalcidol
Sigma Aldrich ₹ 63,456.15
17946
1α-Hydroxyvitamin D3
Sigma Aldrich ₹ 30,483.20
AI67729
41294-56-8 | Alfacalcidol
A2B Chem --

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Description

  • General description: 1α-Hydroxyvitamin D3, also known as alfacalcidol, is a synthetic vitamin D3 analogue, hydroxylated in position one. It is metabolized to 1,25-dihydroxycholecalciferol by 25-hydroxylases.[1]
  • Biochem/physiol Actions: 1α-Hydroxyvitamin D3 facilitates calcium absorption and deposition.[2] It also has an ability to inhibit bone resorption and stimulate bone formation.[3] Alfacalcidol is used for treating various bone diseases such as rickets/osteomalacia, renal osteodystrophy and osteoporosis.[3] It acts as a chemopreventive agent and reduces the risk colitis and carcinogenesis.[4]
  • Packaging: Bottomless glass bottle. Contents are inside inserted fused cone.

SAFETY INFORMATION

Pictograms

GHS06

Signal Word

Danger

Hazard Statements

H300

Precautionary Statements

P301 + P330 + P331 + P310

Hazard Classifications

Acute Tox. 1 Oral

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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biological source:
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Quality Level:
200

Assay:
≥97.0% (HPLC)

form:
powder or crystals

color:
white to off-white

storage temp.:
−20°C

SMILES string:
CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C3\C[C@@H](O)C[C@H](O)C3=C

InChI:
1S/C27H44O2/c1-18(2)8-6-9-19(3)24-13-14-25-21(10-7-15-27(24,25)5)11-12-22-16-23(28)17-26(29)20(22)4/h11-12,18-19,23-26,28-29H,4,6-10,13-17H2,1-3,5H3/b21-11+,22-12-/t19-,23-,24-,25+,26+,27-/m1/s1

InChI key:
OFHCOWSQAMBJIW-AVJTYSNKSA-N

Gene Information:
human ... VDR(7421)

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Cl.COC(=N)CCCCCCC(=N)OC

InChI:
1S/C10H20N2O2.2ClH/c1-13-9(11)7-5-3-4-6-8-10(12)14-2;;/h11-12H,3-8H2,1-2H3;2*1H

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ILKCDNKCNSNFMP-UHFFFAOYSA-N

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rat ... Maoa(29253) , Maob(25750)

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O[C@H]1C[C@@H]2CC[C@H]1C2

InChI:
1S/C7H12O/c8-7-4-5-1-2-6(7)3-5/h5-8H,1-4H2/t5-,6+,7+/m1/s1

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ZQTYQMYDIHMKQB-VQVTYTSYSA-N

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__