Description

• General description: The N-lauroylsarcosine sodium salt is applicable for processes that require tight control of elemental content. This product aids in the solubilization and separation of membrane proteins, glycoproteins, and the isolation of RNA and plasmids. N-lauroylsarcosine sodium salt serves as an antifoaming supplement or as a component of a lysing buffer of bacteria or other cells. It indicates the paramagnetic anisotropy sign change in the micelle mesophase. N-lauroylsarcosine sodium salt inhibits hexokinase and the bacterial flora of human saliva/gut at 0.25%. It also exhibits fungistatic activity in aqueous dispersion (1%). N-lauroylsarcosine (LS) is an anionic surfactant with protein denaturant potency that is structurally similar to sodium lauryl sulfate (SLS). It can inactivate herpes simplex virus (HSV) infectivity in vitro. It is used as a microbicide in topical vaginal formulations to block the transmission of HSV, human immunodeficiency virus type 1 (HIV-1), and possibly other pathogens causing sexually transmitted diseases (STDs).[1]
• Application: N-Lauroylsarcosine sodium salt has been used as a component: of nuclease stop mix, embryo extract buffer to dissociate nonspecifically bound proteins from chromatinof proteinase K solution for the heat denaturation of genomic DNAof 10% (w/v) sarcosyl/0.5 M ethylenediaminetetraacetic acid (EDTA) solution to prepare EDTA-sarcosyl-proteinase (ESP) buffer in the hybridization buffer for in situ hybridization histochemistry[2]in the embryo extract buffer to dissociate nonspecifically bound proteins from chromatin[3]in proteinase K solution to inactivate the enzymes[4]
• Other Notes: Anionic surfactant.