700017P

25-hydroxycholesterol-3-sulfate

Manufacturer: Sigma Aldrich

CAS Number: 884905-07-1

Synonym(S): 5-cholesten-3beta, 25-diol 3-sulfate; 25HC3S

Select a Size

Pack Size SKU Availability Price
5 MG 700017P-5-MG In Stock ₹ 46,980.50
10 MG 700017P-10-MG In Stock ₹ 70,232.60

700017P - 5 MG

₹ 46,980.50

In Stock

Quantity

1

Base Price: ₹ 46,980.50

GST (18%): ₹ 8,456.49

Total Price: ₹ 55,436.99

description

25-hydroxycholesterol-3-sulfate (sodium salt)

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (700017P-10mg)pkg of 1 × 5 mg (700017P-5mg)

manufacturer/tradename

Avanti Polar Lipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@]12[C@]([C@](CC[C@H](OS(=O)([O-])=O)C3)(C)C3=CC2)([H])CC[C@@]4(C)[C@@]1([H])CC[C@]4([H])[C@]([H])(C)CCCC(C)(O)C.[Na+]

Other Options

Image Product Name Manufacturer Price Range
BL09981
884905-07-1 | 25-hydroxycholesterol-3-sulfate (sodium salt)
A2B Chem ₹ 1,41,243.00 - ₹ 1,90,104.00

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Description

  • General description: 25-hydroxycholesterol-3-sulfate (25OHC3S) is a nuclear oxysterol.[1] It accumulates in hepatocyte nuclei upon steroidogenic acute regulatory protein (STARD1) overexpression.[2]
  • Application: 25-hydroxycholesterol-3-sulfate has been used to induce anti-inflammatory responses and understand its effect on lymphocyte migration.[3] It has also been used as an oxysterol sulfate standard in mass spectroscopy and liquid chromatography methods.[4]
  • Biochem/physiol Actions: 25-hydroxycholesterol-3-sulfate (25OHC3S) is involved in lipid homeostasis in liver[5] and is a lipid metabolism regulator.[1] 25OHC3S acts on liver X receptor (LXR) and sterol regulatory element-binding protein (SREBP) and inhibits cholesterol synthesis by downregulating enzymes of the biosynthesis pathway in hepatocytes and macrophages.[5] It also acts an agonist for peroxisome proliferator-activated receptor γ (PPAR-γ) and modulates the nuclear factor κ-light-chain-enhancer (NF-κB) based inflammatory response.[2] 25OHC3S modulates tumor necrosis factor α (TNFα)-induced inflammatory response in hepatocytes.[1]
  • Packaging: 5 mL Amber Glass Screw Cap Vial (700017P-10mg)

Compare Similar Items

Show Difference

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Sigma Aldrich

700017P

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description:
25-hydroxycholesterol-3-sulfate (sodium salt)

Assay:
>99% (TLC)

form:
powder

packaging:
pkg of 1 × 10 mg (700017P-10mg)pkg of 1 × 5 mg (700017P-5mg)

manufacturer/tradename:
Avanti Polar Lipids

shipped in:
dry ice

storage temp.:
−20°C

SMILES string:
[H][C@@]12[C@]([C@](CC[C@H](OS(=O)([O-])=O)C3)(C)C3=CC2)([H])CC[C@@]4(C)[C@@]1([H])CC[C@]4([H])[C@]([H])(C)CCCC(C)(O)C.[Na+]

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cholest-5-ene-3β,24(R/S)-diol-d7

Assay:
>99% (TLC)

form:
powder

packaging:
pkg of 1 × 1 mg (700018P-1mg)pkg of 1 × 5 mg (700018P-5mg)

manufacturer/tradename:
Avanti Polar Lipids

shipped in:
dry ice

storage temp.:
−20°C

SMILES string:
__

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description:
cholest-5-ene-3β,25-diol

Assay:
>99% (TLC)

form:
powder

packaging:
pkg of 1 × 10 mg (700019P-10mg)pkg of 1 × 100 mg (700019P-100mg)pkg of 1 × 5 mg (700019P-5mg)

manufacturer/tradename:
Avanti Polar Lipids

shipped in:
dry ice

storage temp.:
−20°C

SMILES string:
__

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Sigma Aldrich

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description:
__

Assay:
__

form:
powder

packaging:
pkg of 1 × 1 mg (700024P-1mg)

manufacturer/tradename:
Avanti Polar Lipids

shipped in:
dry ice

storage temp.:
−20°C

SMILES string:
__