700060P

desmosterol

Manufacturer: Sigma Aldrich

CAS Number: 313-04-2

Synonym(S): 24-dehydrocholesterol; 5,24-cholestadien-3β-ol; 110798

Select a Size

Pack Size SKU Availability Price
5 MG 700060P-5-MG In Stock ₹ 27,831.08
10 MG 700060P-10-MG In Stock ₹ 43,559.80

700060P - 5 MG

₹ 27,831.08

In Stock

Quantity

1

Base Price: ₹ 27,831.08

GST (18%): ₹ 5,009.594

Total Price: ₹ 32,840.674

description

3β-hydroxy-5,24-cholestadiene

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (700060P-10mg)pkg of 1 × 5 mg (700060P-5mg)

manufacturer/tradename

Avanti Polar Lipids

shipped in

dry ice

storage temp.

−20°C

InChI

1S/C27H44O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h7,9,19,21-25,28H,6,8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1

InChI key

AVSXSVCZWQODGV-DPAQBDIFSA-N

Other Options

Image Product Name Manufacturer Price Range
50-247-0162
eMolecules​ Medchem Express / Desmosterol / 5mg / 686240849 / HY-113224 / / 313-04-2 / MFCD00056432 / 384.648 / C27H44O
eMolecules​ ₹ 23,929.42
CS-0059348
Desmosterol
ChemScene ₹ 5,903.64 - ₹ 54,758.40
AF59093
313-04-2 | Desmosterol
A2B Chem ₹ 2,823.48 - ₹ 19,849.92

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Description

  • General description: Desmosterol lacks a double bond between C24 and C25 compared to cholesterol. It is present in the membrane of spermatozoa and astrocytes[1] and is the major brain sterol.[2]
  • Application: Desmosterol has been used as a sterol to test its interaction with human protein Mincle[3] and as an internal standard in ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS).[4] It may be used as in the preparation of lipid monolayers.[5]
  • Biochem/physiol Actions: Desmosterol is a precursor of cholesterol in the Bloch pathway and the enzyme 24-dehydrocholesterol reductase catalyzes this step.[1] Desmosterol accumulates during impairment of 24-dehydrocholesterol reductase enzyme thereby leading to desmosterolosis.[1] Desmosterol is a liver X receptor (LXR) agonist .[2] It is a potential therapeutic target for treating the neurodegenerative disorder. Desmosterol regulates inflammatory signaling in macrophages.[6]
  • Packaging: 5 mL Amber Glass Screw Cap Vial (700060P-10mg)

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Compare Similar Items

Show Difference

Img

Sigma Aldrich

700060P

--


description:
3β-hydroxy-5,24-cholestadiene

Assay:
>99% (TLC)

form:
powder

packaging:
pkg of 1 × 10 mg (700060P-10mg)pkg of 1 × 5 mg (700060P-5mg)

manufacturer/tradename:
Avanti Polar Lipids

shipped in:
dry ice

storage temp.:
−20°C

InChI:
1S/C27H44O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h7,9,19,21-25,28H,6,8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1

InChI key:
AVSXSVCZWQODGV-DPAQBDIFSA-N

Img

Sigma Aldrich

700061P

--


description:
cholest-5-ene-3β,24(S)-diol

Assay:
>99% (TLC)

form:
powder

packaging:
pkg of 1 × 1 mg (700061P-1mg)pkg of 1 × 5 mg (700061P-5mg)

manufacturer/tradename:
Avanti Polar Lipids

shipped in:
dry ice

storage temp.:
−20°C

InChI:
1S/C27H46O2/c1-17(2)25(29)11-6-18(3)22-9-10-23-21-8-7-19-16-20(28)12-14-26(19,4)24(21)13-15-27(22,23)5/h7,17-18,20-25,28-29H,6,8-16H2,1-5H3/t18-,20+,21+,22-,23+,24+,25+,26+,27-/m1/s1

InChI key:
IOWMKBFJCNLRTC-XWXSNNQWSA-N

Img

Sigma Aldrich

700065P

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description:
4-cholesten-3-one

Assay:
>99% (TLC)

form:
powder

packaging:
pkg of 1 × 5 mg (700065P-5mg)

manufacturer/tradename:
Avanti Polar Lipids

shipped in:
dry ice

storage temp.:
−20°C

InChI:
1S/C27H44O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h17-19,22-25H,6-16H2,1-5H3

InChI key:
NYOXRYYXRWJDKP-UHFFFAOYSA-N

Img

Sigma Aldrich

700066P

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description:
__

Assay:
>99% (TLC)

form:
powder

packaging:
pkg of 1 × 5 mg (700066P-5mg)

manufacturer/tradename:
Avanti Polar Lipids 700066P

shipped in:
dry ice

storage temp.:
−70°C

InChI:
1S/C27H44O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9-10,18-19,21,23-25,28H,6-8,11-17H2,1-5H3

InChI key:
UCTLRSWJYQTBFZ-UHFFFAOYSA-N