700061P
24(S)-hydroxycholesterol
Manufacturer: Sigma Aldrich
CAS Number: 474-73-7
Synonym(S): 5-cholestene-3β,24-diol; 24-hydroxycholest-5-en-3-ol
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 MG | 700061P-1-MG | In Stock | ₹ 51,278.03 |
| 5 MG | 700061P-5-MG | In Stock | ₹ 2,07,926.60 |
700061P - 1 MG
In Stock
Quantity
1
Base Price: ₹ 51,278.03
GST (18%): ₹ 9,230.045
Total Price: ₹ 60,508.075
description
cholest-5-ene-3β,24(S)-diol
Assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (700061P-1mg)pkg of 1 × 5 mg (700061P-5mg)
manufacturer/tradename
Avanti Polar Lipids
shipped in
dry ice
storage temp.
−20°C
InChI
1S/C27H46O2/c1-17(2)25(29)11-6-18(3)22-9-10-23-21-8-7-19-16-20(28)12-14-26(19,4)24(21)13-15-27(22,23)5/h7,17-18,20-25,28-29H,6,8-16H2,1-5H3/t18-,20+,21+,22-,23+,24+,25+,26+,27-/m1/s1
InChI key
IOWMKBFJCNLRTC-XWXSNNQWSA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Sigma Aldrich Fine Chemicals Biosciences 24(S)-Hydroxycholesterol >=98% (HPLC) | 474-73-7 | 5MG | Sigma Aldrich Fine Chemicals Biosciences | ₹ 54,621.50 | |
 | 474-73-7 | 24-Hydroxycholesterol | A2B Chem | ₹ 5,304.72 - ₹ 46,287.96 |
Related Products
Description
- General description: 24(S)-hydroxycholesterol (24HC) is synthesized from cholesterol in brain dendrites by the action of enzyme cholesterol 24-hydroxylase (CYP46A1).[1] It is catabolized to bile acids in the liver.[2]
- Application: 24(S)-hydroxycholesterol has been used as an internal standard: in ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS)[3]in liquid chromatography with tandem mass spectrometry (LC-MS/MS) for the quantification of 27-hydroxycholesterol from colorectal tumor samples[4]for quantification of human plasma sterols by liquid chromatography with tandem mass spectrometry (LC MS/MS)[5]
- Biochem/physiol Actions: 24(S)-hydroxycholesterol (24HC) elevated levels are reported in liver inflammation and fibrosis.[2] It is a N-methyl-D-aspartate receptor (NMDAR) modulator.[1] The levels of 24HC are potential indicators of brain development as well as pathology including Alzheimer′s disease (AD) and multiple sclerosis.[6] Polymorphism in the cholesterol 24-hydroxylase (CYP46A1) gene leads to elevated 24HC levels and toxicity. 24HC is a mediator of apoptosis and necroptosis.[7] Elevated levels of 24HC are reported in liver inflammation and fibrosis.[2]
- Packaging: 5 mL Amber Glass Screw Cap Vial (700061P-1mg)
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Compare Similar Items
Show Difference
description: cholest-5-ene-3β,24(S)-diol
Assay: >99% (TLC)
form: powder
packaging: pkg of 1 × 1 mg (700061P-1mg)pkg of 1 × 5 mg (700061P-5mg)
manufacturer/tradename: Avanti Polar Lipids
shipped in: dry ice
storage temp.: −20°C
InChI: 1S/C27H46O2/c1-17(2)25(29)11-6-18(3)22-9-10-23-21-8-7-19-16-20(28)12-14-26(19,4)24(21)13-15-27(22,23)5/h7,17-18,20-25,28-29H,6,8-16H2,1-5H3/t18-,20+,21+,22-,23+,24+,25+,26+,27-/m1/s1
InChI key: IOWMKBFJCNLRTC-XWXSNNQWSA-N
description:
cholest-5-ene-3β,24(S)-diol
Assay:
>99% (TLC)
form:
powder
packaging:
pkg of 1 × 1 mg (700061P-1mg)pkg of 1 × 5 mg (700061P-5mg)
manufacturer/tradename:
Avanti Polar Lipids
shipped in:
dry ice
storage temp.:
−20°C
InChI:
1S/C27H46O2/c1-17(2)25(29)11-6-18(3)22-9-10-23-21-8-7-19-16-20(28)12-14-26(19,4)24(21)13-15-27(22,23)5/h7,17-18,20-25,28-29H,6,8-16H2,1-5H3/t18-,20+,21+,22-,23+,24+,25+,26+,27-/m1/s1
InChI key:
IOWMKBFJCNLRTC-XWXSNNQWSA-N
description: 4-cholesten-3-one
Assay: >99% (TLC)
form: powder
packaging: pkg of 1 × 5 mg (700065P-5mg)
manufacturer/tradename: Avanti Polar Lipids
shipped in: dry ice
storage temp.: −20°C
InChI: 1S/C27H44O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h17-19,22-25H,6-16H2,1-5H3
InChI key: NYOXRYYXRWJDKP-UHFFFAOYSA-N
description:
4-cholesten-3-one
Assay:
>99% (TLC)
form:
powder
packaging:
pkg of 1 × 5 mg (700065P-5mg)
manufacturer/tradename:
Avanti Polar Lipids
shipped in:
dry ice
storage temp.:
−20°C
InChI:
1S/C27H44O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h17-19,22-25H,6-16H2,1-5H3
InChI key:
NYOXRYYXRWJDKP-UHFFFAOYSA-N
description: __
Assay: >99% (TLC)
form: powder
packaging: pkg of 1 × 5 mg (700066P-5mg)
manufacturer/tradename: Avanti Polar Lipids 700066P
shipped in: dry ice
storage temp.: −70°C
InChI: 1S/C27H44O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9-10,18-19,21,23-25,28H,6-8,11-17H2,1-5H3
InChI key: UCTLRSWJYQTBFZ-UHFFFAOYSA-N
description:
__
Assay:
>99% (TLC)
form:
powder
packaging:
pkg of 1 × 5 mg (700066P-5mg)
manufacturer/tradename:
Avanti Polar Lipids 700066P
shipped in:
dry ice
storage temp.:
−70°C
InChI:
1S/C27H44O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9-10,18-19,21,23-25,28H,6-8,11-17H2,1-5H3
InChI key:
UCTLRSWJYQTBFZ-UHFFFAOYSA-N
description: 24,25-dihydrolanosterol
Assay: >99% (TLC)
form: powder
packaging: pkg of 1 × 1 mg (700067P-1mg)pkg of 1 × 5 mg (700067P-5mg)
manufacturer/tradename: Avanti Polar Lipids
shipped in: dry ice
storage temp.: −20°C
InChI: __
InChI key: __
description:
24,25-dihydrolanosterol
Assay:
>99% (TLC)
form:
powder
packaging:
pkg of 1 × 1 mg (700067P-1mg)pkg of 1 × 5 mg (700067P-5mg)
manufacturer/tradename:
Avanti Polar Lipids
shipped in:
dry ice
storage temp.:
−20°C
InChI:
__
InChI key:
__