700058P

22(R)-hydroxycholesterol

Manufacturer: Sigma Aldrich

CAS Number: 17954-98-2

Synonym(S): 5-cholestene-3β,22-diol; 22-hydroxycholest-5-en-3-ol

Select a Size

Pack Size SKU Availability Price
1 MG 700058P-1-MG In Stock ₹ 15,382.33
5 MG 700058P-5-MG In Stock ₹ 54,687.90

700058P - 1 MG

₹ 15,382.33

In Stock

Quantity

1

Base Price: ₹ 15,382.33

GST (18%): ₹ 2,768.819

Total Price: ₹ 18,151.149

description

cholest-5-ene-3β,22(R)-diol

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (700058P-1mg)pkg of 1 × 5 mg (700058P-5mg)

manufacturer/tradename

Avanti Polar Lipids

shipped in

dry ice

storage temp.

−20°C

InChI

1S/C27H46O2/c1-17(2)6-11-25(29)18(3)22-9-10-23-21-8-7-19-16-20(28)12-14-26(19,4)24(21)13-15-27(22,23)5/h7,17-18,20-25,28-29H,6,8-16H2,1-5H3/t18-,20-,21-,22+,23-,24-,25+,26-,27+/m0/s1

InChI key

RZPAXNJLEKLXNO-GFKLAVDKSA-N

Other Options

Image Product Name Manufacturer Price Range
H9384
22(R)-Hydroxycholesterol
Sigma Aldrich ₹ 10,424.48 - ₹ 40,279.83
CS-0066924
22(R)-Hydroxycholesterol
ChemScene ₹ 6,502.56 - ₹ 44,491.20
AB02296
17954-98-2 | (8S,9S,10R,13S,14S,17R)-17-((2S,3R)-3-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol
A2B Chem ₹ 4,705.80 - ₹ 36,106.32

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Description

  • General description: 22(R)-hydroxycholesterol is a diastereomer of 22(S)-hydroxycholesterol.[1] It is present in neonate brain.[2]
  • Application: 22(R)-hydroxycholesterol has been used as a liver X receptor (LXR) ligand in breast cancer cell lines.[3] It may be used as an internal standard to spike mouse brain tissue samples for ultra-performance liquid chromatography–high resolution mass spectrometry (UPLC-ESI-HRMS) analysis.[4]
  • Biochem/physiol Actions: 22(R)-hydroxycholesterol (22(R)-HC) is a liver X receptor (LXR) ligand.[5]. 22(R)-HC in combination with other oxysterols promote mesenchymal stem cell osteogenesis.[6] It regulates cholesterol homeostasis.[7] Low levels of 22(R)-HC is observed in Alzheimer′s disease and it may be implicated in neuroinflammation and neurodegenerative diseases.[2] 22(R)-hydroxycholesterol also suppresses prostate tumor progression.[8]
  • Packaging: 5 mL Amber Glass Screw Cap Vial (700058P-1mg)

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Compare Similar Items

Show Difference

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Sigma Aldrich

700058P

--


description:
cholest-5-ene-3β,22(R)-diol

Assay:
>99% (TLC)

form:
powder

packaging:
pkg of 1 × 1 mg (700058P-1mg)pkg of 1 × 5 mg (700058P-5mg)

manufacturer/tradename:
Avanti Polar Lipids

shipped in:
dry ice

storage temp.:
−20°C

InChI:
1S/C27H46O2/c1-17(2)6-11-25(29)18(3)22-9-10-23-21-8-7-19-16-20(28)12-14-26(19,4)24(21)13-15-27(22,23)5/h7,17-18,20-25,28-29H,6,8-16H2,1-5H3/t18-,20-,21-,22+,23-,24-,25+,26-,27+/m0/s1

InChI key:
RZPAXNJLEKLXNO-GFKLAVDKSA-N

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Sigma Aldrich

700059P

--


description:
25,26,26,26,27,27-hexadeuterocholest-5-ene-3β,27-diol

Assay:
>99% (TLC)

form:
powder

packaging:
pkg of 1 × 1 mg (700059P-1mg)

manufacturer/tradename:
Avanti Polar Lipids

shipped in:
dry ice

storage temp.:
−20°C

InChI:
__

InChI key:
__

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Sigma Aldrich

70006-M

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description:
__

Assay:
__

form:
liquid

packaging:
__

manufacturer/tradename:
Novagen®

shipped in:
__

storage temp.:
−20°C

InChI:
__

InChI key:
__

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Sigma Aldrich

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description:
3β-hydroxy-5,24-cholestadiene

Assay:
>99% (TLC)

form:
powder

packaging:
pkg of 1 × 10 mg (700060P-10mg)pkg of 1 × 5 mg (700060P-5mg)

manufacturer/tradename:
Avanti Polar Lipids

shipped in:
dry ice

storage temp.:
−20°C

InChI:
1S/C27H44O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h7,9,19,21-25,28H,6,8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1

InChI key:
AVSXSVCZWQODGV-DPAQBDIFSA-N