700035P
7β-hydroxycholesterol
Manufacturer: Sigma Aldrich
CAS Number: 566-27-8
Synonym(S): cholest-5-ene-3b,7b-diol; 110809
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 5 MG | 700035P-5-MG | In Stock | ₹ 22,754.15 |
| 10 MG | 700035P-10-MG | In Stock | ₹ 35,527.65 |
| 25 MG | 700035P-25-MG | In Stock | ₹ 72,051.20 |
700035P - 5 MG
In Stock
Quantity
1
Base Price: ₹ 22,754.15
GST (18%): ₹ 4,095.747
Total Price: ₹ 26,849.897
description
cholest-5-en-3β,7β-diol
Assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 10 mg (700035P-10mg)pkg of 1 × 25 mg (700035P-25mg)pkg of 1 × 5 mg (700035P-5mg)
manufacturer/tradename
Avanti Polar Lipids
shipped in
dry ice
storage temp.
−20°C
InChI
1S/C27H46O2/c1-17(2)7-6-8-18(3)21-9-10-22-25-23(12-14-27(21,22)5)26(4)13-11-20(28)15-19(26)16-24(25)29/h16-18,20-25,28-29H,6-15H2,1-5H3/t18-,20?,21-,22+,23+,24+,25+,26+,27-/m1/s1
InChI key
OYXZMSRRJOYLLO-ISPKDCJXSA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | 7β-Hydroxycholesterol | Sigma Aldrich | ₹ 15,945.23 - ₹ 42,271.63 | |
 | 566-27-8 | (3S,7R,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol | A2B Chem | ₹ 11,807.28 - ₹ 43,977.84 |
Related Products
Description
- General description: 7β-hydroxycholesterol (7β-OHC) is an oxysterol synthesized by the oxidation of the low-density lipoprotein (LDL).[1] It is primarily catabolized to bile acid in the liver.[2]
- Application: 7β-hydroxycholesterol has been used: as an internal oxysterol standard in liquid chromatography–mass spectrometry (LC-MS) for the quantification of sterols associated with cholesterol biosynthesis in neurospheres post inhibitor AY9944 treatment[3]to reconstitute high-density lipoprotein (HDL) for anti-apoptotic studies in insulinoma cell line INS1e[4]as a cholesterol oxidation product standard in ultra high-performance liquid chromatography (UHPLC) coupled with high- resolution quadrupole time-of-flight (Q-TOF) mass spectrometry[5]
- Biochem/physiol Actions: 7β-hydroxycholesterol (7β-OHC) favors apoptosis via caspase 8 based mitochondrial pathway.[1] It also hinders cancer cell survival by generating reactive oxygen species(ROS).[6] The levels of 7β-OHC are elevated in the cerebrospinal fluid of multiple sclerosis and Alzheimer′s disease (AD) patients. 7β-OHC also promotes oxiapoptophagy and demyelination.[2] It activates mitogen-activated protein kinases and modulates intracellular Ca2+ homeostasis and may contribute to the disorganization of Golgi and endoplasmic reticulum membranes.[7]
- Packaging: 5 mL Amber Glass Screw Cap Vial (700035P-10mg)
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Compare Similar Items
Show Difference
description: cholest-5-en-3β,7β-diol
Assay: >99% (TLC)
form: powder
packaging: pkg of 1 × 10 mg (700035P-10mg)pkg of 1 × 25 mg (700035P-25mg)pkg of 1 × 5 mg (700035P-5mg)
manufacturer/tradename: Avanti Polar Lipids
shipped in: dry ice
storage temp.: −20°C
InChI: 1S/C27H46O2/c1-17(2)7-6-8-18(3)21-9-10-22-25-23(12-14-27(21,22)5)26(4)13-11-20(28)15-19(26)16-24(25)29/h16-18,20-25,28-29H,6-15H2,1-5H3/t18-,20?,21-,22+,23+,24+,25+,26+,27-/m1/s1
InChI key: OYXZMSRRJOYLLO-ISPKDCJXSA-N
description:
cholest-5-en-3β,7β-diol
Assay:
>99% (TLC)
form:
powder
packaging:
pkg of 1 × 10 mg (700035P-10mg)pkg of 1 × 25 mg (700035P-25mg)pkg of 1 × 5 mg (700035P-5mg)
manufacturer/tradename:
Avanti Polar Lipids
shipped in:
dry ice
storage temp.:
−20°C
InChI:
1S/C27H46O2/c1-17(2)7-6-8-18(3)21-9-10-22-25-23(12-14-27(21,22)5)26(4)13-11-20(28)15-19(26)16-24(25)29/h16-18,20-25,28-29H,6-15H2,1-5H3/t18-,20?,21-,22+,23+,24+,25+,26+,27-/m1/s1
InChI key:
OYXZMSRRJOYLLO-ISPKDCJXSA-N
description: cholest-5-ene-3β,4β-diol
Assay: >99% (TLC)
form: powder
packaging: pkg of 1 × 10 mg (700036P-10mg)pkg of 1 × 5 mg (700036P-5mg)
manufacturer/tradename: Avanti Polar Lipids
shipped in: dry ice
storage temp.: −20°C
InChI: 1S/C27H46O2/c1-17(2)7-6-8-18(3)20-11-12-21-19-9-10-23-25(29)24(28)14-16-27(23,5)22(19)13-15-26(20,21)4/h10,17-22,24-25,28-29H,6-9,11-16H2,1-5H3
InChI key: CZDKQKOAHAICSF-UHFFFAOYSA-N
description:
cholest-5-ene-3β,4β-diol
Assay:
>99% (TLC)
form:
powder
packaging:
pkg of 1 × 10 mg (700036P-10mg)pkg of 1 × 5 mg (700036P-5mg)
manufacturer/tradename:
Avanti Polar Lipids
shipped in:
dry ice
storage temp.:
−20°C
InChI:
1S/C27H46O2/c1-17(2)7-6-8-18(3)20-11-12-21-19-9-10-23-25(29)24(28)14-16-27(23,5)22(19)13-15-26(20,21)4/h10,17-22,24-25,28-29H,6-9,11-16H2,1-5H3
InChI key:
CZDKQKOAHAICSF-UHFFFAOYSA-N
description: __
Assay: 96%
form: solid
packaging: __
manufacturer/tradename: __
shipped in: __
storage temp.: __
InChI: 1S/2C2H8N2.2HI.2NO3.2Pt/c2*3-1-2-4;;;2*2-1(3)4;;/h2*1-4H2;2*1H;;;;/q;;;;2*-1;2*+2/p-2
InChI key: NRXMBGQJNZDBOD-UHFFFAOYSA-L
description:
__
Assay:
96%
form:
solid
packaging:
__
manufacturer/tradename:
__
shipped in:
__
storage temp.:
__
InChI:
1S/2C2H8N2.2HI.2NO3.2Pt/c2*3-1-2-4;;;2*2-1(3)4;;/h2*1-4H2;2*1H;;;;/q;;;;2*-1;2*+2/p-2
InChI key:
NRXMBGQJNZDBOD-UHFFFAOYSA-L
description: __
Assay: __
form: powder
packaging: pkg of 1 × 1 mg (700037P-1mg)
manufacturer/tradename: Avanti Polar Lipids
shipped in: dry ice
storage temp.: −20°C
InChI: __
InChI key: __
description:
__
Assay:
__
form:
powder
packaging:
pkg of 1 × 1 mg (700037P-1mg)
manufacturer/tradename:
Avanti Polar Lipids
shipped in:
dry ice
storage temp.:
−20°C
InChI:
__
InChI key:
__