700015P

7-ketocholesterol

Manufacturer: Sigma Aldrich

CAS Number: 566-28-9

Synonym(S): 7-oxocholesterol; 7-oxo-5-cholesten-3β-ol-7-one; 5-cholesten-3β-ol-7-one; 3β-hydroxycholest-5-en-7-one; 110806

Select a Size

Pack Size SKU Availability Price
5 MG 700015P-5-MG In Stock ₹ 12,243.08
50 MG 700015P-50-MG In Stock ₹ 79,736.95
100 MG 700015P-100-MG In Stock ₹ 1,42,110.60

700015P - 5 MG

₹ 12,243.08

In Stock

Quantity

1

Base Price: ₹ 12,243.08

GST (18%): ₹ 2,203.754

Total Price: ₹ 14,446.834

description

3β-hydroxy-5-cholestene-7-one

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 100 mg (700015P-100mg)pkg of 1 × 5 mg (700015P-5mg)pkg of 1 × 50 mg (700015P-50mg)

manufacturer/tradename

Avanti Polar Lipids

shipped in

dry ice

storage temp.

−20°C

InChI

1S/C27H44O2/c1-17(2)7-6-8-18(3)21-9-10-22-25-23(12-14-27(21,22)5)26(4)13-11-20(28)15-19(26)16-24(25)29/h16-18,20-23,25,28H,6-15H2,1-5H3/t18-,20+,21-,22+,23+,25+,26+,27-/m1/s1

InChI key

YIKKMWSQVKJCOP-ABXCMAEBSA-N

Other Options

Image Product Name Manufacturer Price Range
50-183-2737
Sigma Aldrich Fine Chemicals Biosciences 5-Cholesten-3beta-ol-7-one >=90% | 566-28-9 | MFCD00010474 | 100MG
Sigma Aldrich Fine Chemicals Biosciences ₹ 9,694.80
C2394
5-Cholesten-3β-ol-7-one
Sigma Aldrich ₹ 6,982.13 - ₹ 30,201.75
CS-0061839
7-Ketocholesterol
ChemScene ₹ 4,278.00 - ₹ 47,913.60
AG65311
566-28-9 | 7-Ketocholesterol
A2B Chem ₹ 4,449.12 - ₹ 54,758.40

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Description

  • General description: 7-ketocholesterol is a major oxidation product of cholesterol.[1]
  • Application: <ul><li><strong>Cytoprotective effects of linolenic acid on 7-ketocholesterol-induced damage:</strong> This study highlights how specific fatty acids can mitigate the toxic effects of 7-ketocholesterol in neural and vascular cells, emphasizing potential therapeutic applications for neurodegenerative and cardiovascular diseases (Yammine et al., 2024).</li></ul>
  • Biochem/physiol Actions: 7-ketocholesterol is a strong inhibitor of cytochrome P450 7A1. It modulates cholesterol homeostasis, cytotoxicity and apoptosis. 7-ketocholesterol stimulates inflammation, growth inhibition and vascular endothelial growth factor.[2] Cellular accumulation of 7-ketocholesterol enhances oxidative stress, endoplasmic reticulum stress and apoptosis in macrophages.[3]
  • Packaging: 5 mL Amber Glass Screw Cap Vial (700015P-100mg)

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Compare Similar Items

Show Difference

Img

Sigma Aldrich

700015P

--


description:
3β-hydroxy-5-cholestene-7-one

Assay:
>99% (TLC)

form:
powder

packaging:
pkg of 1 × 100 mg (700015P-100mg)pkg of 1 × 5 mg (700015P-5mg)pkg of 1 × 50 mg (700015P-50mg)

manufacturer/tradename:
Avanti Polar Lipids

shipped in:
dry ice

storage temp.:
−20°C

InChI:
1S/C27H44O2/c1-17(2)7-6-8-18(3)21-9-10-22-25-23(12-14-27(21,22)5)26(4)13-11-20(28)15-19(26)16-24(25)29/h16-18,20-23,25,28H,6-15H2,1-5H3/t18-,20+,21-,22+,23+,25+,26+,27-/m1/s1

InChI key:
YIKKMWSQVKJCOP-ABXCMAEBSA-N

Img

Sigma Aldrich

700016P

--


description:
cholesterol 3-sulfate (sodium salt)

Assay:
>99% (TLC)

form:
powder

packaging:
pkg of 1 × 1 g (700016P-1g)pkg of 1 × 25 mg (700016P-25mg)pkg of 1 × 500 mg (700016P-500mg)

manufacturer/tradename:
Avanti Polar Lipids 700016P

shipped in:
dry ice

storage temp.:
−20°C

InChI:
1S/C27H46O4S.Na/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(31-32(28,29)30)13-15-26(20,4)25(22)14-16-27(23,24)5;/h9,18-19,21-25H,6-8,10-17H2,1-5H3,(H,28,29,30);/q;+1/p-1/t19-,21+,22+,23-,24+,25+,26+,27-;/m1./s1

InChI key:
LMPVQXVJTZWENW-KPNWGBFJSA-M

Img

Sigma Aldrich

700017P

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description:
25-hydroxycholesterol-3-sulfate (sodium salt)

Assay:
>99% (TLC)

form:
powder

packaging:
pkg of 1 × 10 mg (700017P-10mg)pkg of 1 × 5 mg (700017P-5mg)

manufacturer/tradename:
Avanti Polar Lipids

shipped in:
dry ice

storage temp.:
−20°C

InChI:
__

InChI key:
__

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Sigma Aldrich

700018P

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description:
cholest-5-ene-3β,24(R/S)-diol-d7

Assay:
>99% (TLC)

form:
powder

packaging:
pkg of 1 × 1 mg (700018P-1mg)pkg of 1 × 5 mg (700018P-5mg)

manufacturer/tradename:
Avanti Polar Lipids

shipped in:
dry ice

storage temp.:
−20°C

InChI:
__

InChI key:
__