700184M

desmosterol (D6) ester

Manufacturer: Sigma Aldrich

CAS Number: 2260669-31-4

Synonym(S): 111014

Select a Size

Pack Size SKU Availability Price
1 MG 700184M-1-MG In Stock ₹ 21,779.90

700184M - 1 MG

₹ 21,779.90

In Stock

Quantity

1

Base Price: ₹ 21,779.90

GST (18%): ₹ 3,920.382

Total Price: ₹ 25,700.282

Assay

>99% (TLC)

form

methylene chloride solution

packaging

pkg of 1 × 1 mL (700184M-1mg)

manufacturer/tradename

Avanti Polar Lipids 700184M

concentration

1 mg/mL (700184M-1mg)

shipped in

dry ice

storage temp.

−20°C

Other Options

Image Product Name Manufacturer Price Range
BN90457
2260669-31-4 | Desmosterol ester-d6
A2B Chem ₹ 85,731.12

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Description

  • General description: Desmosterol is a precursor of cholesterol synthesis and the enzyme 24-dehydrocholesterol reductase catalyzes this step.[1] It lacks a double bond between C24 and C25, which is present in cholesterol.[1] Desmosterol is the major brain sterol[2] and is localized in spermatozoa membrane and astrocytes.[1] Desmosterol (D6) ester is a deuterated desmosterol with octadecanoic acid.
  • Biochem/physiol Actions: Desmosterol is a liver X receptor (LXR) agonist[2] and it regulates inflammatory signaling in macrophages.[3] Desmosterol accumulates during impairment of 24-dehydrocholesterol reductase enzyme thereby leading to desmosterolosis.[1] It is a potential therapeutic target for treating the neurodegenerative disorder.[3]
  • Packaging: 5 mL Clear Glass Sealed Ampule (700184M-1mg)

SAFETY INFORMATION

Pictograms

GHS08,GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H336,H351

Precautionary Statements

P202 - P261 - P264 - P302 + P352 - P305 + P351 + P338 - P308 + P313

Hazard Classifications

Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Central nervous system

WGK

WGK 2

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Sigma Aldrich

700184M

--


Assay:
>99% (TLC)

form:
methylene chloride solution

packaging:
pkg of 1 × 1 mL (700184M-1mg)

manufacturer/tradename:
Avanti Polar Lipids 700184M

concentration:
1 mg/mL (700184M-1mg)

shipped in:
dry ice

storage temp.:
−20°C

Img

Sigma Aldrich

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Assay:
>99% (TLC)

form:
methylene chloride solution

packaging:
pkg of 1 × 1 mL (700185M-1mg)

manufacturer/tradename:
Avanti Polar Lipids 700185M

concentration:
1 mg/mL (700185M-1mg)

shipped in:
dry ice

storage temp.:
−20°C

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>99% (TLC)

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methylene chloride solution

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pkg of 1 × 1 mL (700186M-1mg)

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concentration:
1 mg/mL (700186M-1mg)

shipped in:
dry ice

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__

shipped in:
dry ice

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−20°C