72345

Nicotinamide

≥98.5% (HPLC)

Manufacturer: Sigma Aldrich

CAS Number: 98-92-0

Synonym(S): Niacinamide, Nicotinic acid amide, Pyridine-3-carboxylic acid amide, Vitamin B3, Vitamin PP

Select a Size

Pack Size SKU Availability Price
50 G 72345-50-G In Stock ₹ 2,901.10
250 G 72345-250-G In Stock ₹ 5,228.48
1 KG 72345-1-KG In Stock ₹ 9,720.85

72345 - 50 G

₹ 2,901.10

In Stock

Quantity

1

Base Price: ₹ 2,901.10

GST (18%): ₹ 522.198

Total Price: ₹ 3,423.298

biological source

synthetic

Quality Level

200

Assay

≥98.5% (HPLC)

form

powder

color

colorless to white

mp

128-131 °C (lit.)128-131 °C

SMILES string

NC(=O)c1cccnc1

InChI

1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)

InChI key

DFPAKSUCGFBDDF-UHFFFAOYSA-N

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Description

  • General description: Nicotinamide is synthesized in the liver from nicotinic acid. It is also produced as a result of nicotinamide adenine dinucleotide (NAD+) hydrolysis.[1]
  • Application: Nicotinamide has been used:as a precursor to study its effect on nicotinamide adenine dinucleotide (NAD) concentration in NAD-deficient mammalian mitochondria[2]as an inhibitor of sirtuin (SIRT) family of deacetylases in in vitro serine hydroxymethyltransferase 2 (SHMT2) deacetylation assay[3]to study its effect on ischemia-reperfusion (I-R) injury-induced cell death in ptenαm/m mice[4]
  • Biochem/physiol Actions: Nicotinamide is an amide derivative of vitamin B3 and a PARP inhibitor

SAFETY INFORMATION

Pictograms

GHS07

Signal Word

Warning

Hazard Statements

H319

Precautionary Statements

P264 - P280 - P305 + P351 + P338 - P337 + P313

Hazard Classifications

Eye Irrit. 2

WGK

WGK 1

Flash Point(F)

closed cup

Flash Point(C)

closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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≥98.5% (HPLC)

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powder

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colorless to white

mp:
128-131 °C (lit.)128-131 °C

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NC(=O)c1cccnc1

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1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)

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DFPAKSUCGFBDDF-UHFFFAOYSA-N

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