840046P
Brain PI(4,5)P2
Manufacturer: Sigma Aldrich
CAS Number: 383907-42-4
Synonym(S): Brain PI(4,5)P2
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 MG | 840046P-1-MG | In Stock | ₹ 48,604.25 |
| 5 MG | 840046P-5-MG | In Stock | ₹ 1,99,569.70 |
| 10 MG | 840046P-10-MG | In Stock | ₹ 3,47,092.80 |
| 25 MG | 840046P-25-MG | In Stock | ₹ 7,68,813.15 |
840046P - 1 MG
In Stock
Quantity
1
Base Price: ₹ 48,604.25
GST (18%): ₹ 8,748.765
Total Price: ₹ 57,353.015
description
L-α-phosphatidylinositol-4,5-bisphosphate (Brain, Porcine) (ammonium salt)
Assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (840046P-1mg)pkg of 1 × 10 mg (840046P-10mg)pkg of 1 × 25 mg (840046P-25mg)pkg of 1 × 5 mg (840046P-5mg)
manufacturer/tradename
Avanti Polar Lipids
lipid type
phosphoglycerides
shipped in
dry ice
storage temp.
−20°C
SMILES string
[H][C@@](COP(O[C@H]1[C@H](O)[C@@H](OP([O-])(O)=O)[C@H](OP(O)([O-])=O)[C@@H](O)[C@H]1O)([O-])=O)(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[NH4+].[NH4+].[NH4+]
InChI
1S/C47H85O19P3.3H3N/c1-3-5-7-9-11-13-15-17-19-20-22-24-26-28-30-32-34-36-41(49)63-39(37-61-40(48)35-33-31-29-27-25-23-21-18-16-14-12-10-8-6-4-2)38-62-69(59,60)66-45-42(50)43(51)46(64-67(53,54)55)47(44(45)52)65-68(56,57)58;;;/h11,13,17,19,22,24,28,30,39,42-47,50-52H,3-10,12,14-16,18,20-21,23,25-27,29,31-38H2,1-2H3,(H,59,60)(H2,53,54,55)(H2,56,57,58);3*1H3/b13-11-,19-17-,24-22-,30-28-;;;/t39-,42?,43+,44?,45-,46?,47?;;;/m1.../s1
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Avanti Polar Lipids L-α-phosphatidylinositol-4,5-bisphosphate (Brain, Porcine) (ammonium salt), 383907-42-4, MFCD28901390, 10 mg | Avanti Polar Lipids | ₹ 3,59,541.94 | |
 | Brain PI(4,5)P2 | Sigma Aldrich | ₹ 45,887.40 - ₹ 7,26,948.00 | |
 | 383907-42-4 | L-α-phosphatidylinositol-4,5-bisphosphate (Brain, Porcine) (ammonium salt) | A2B Chem | ₹ 1,62,820.68 - ₹ 19,71,815.76 |
Related Products
Description
- General description: Although PI(4,5)P2 is a minor component of cell membranes, it plays a critical role as a substrate for a number of important signaling proteins. PI(4,5)P2 is an intermediate in the IP3/DAG pathway where it is hydrolyzed by phospholipase C to liberate the second messengers, inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG). PI(4,5)P2 is also a substrate for PI 3-kinase where it is phosphorylated to PI(3,4,5)P3, an activator of downstream signaling components such as the protein kinase AKT.
- Application: Brain PI(4,5)P2 has been used:in the preparation of Folch liposome[3]in the preparation of giant unilamellar vesicles and multilamellar lipid sheets[4]as a substrate for rubidium flux assay[5]in the biochemical reaction assay mixture for various lipid kinases like Phosphatidylinositol-3-kinase gamma (PI3Kγ), Phosphatidylinositol-3-kinase beta (PI3Kβ), Phosphatidylinositol-3-kinase gamma (PI3Kα)[1]
- Biochem/physiol Actions: Phosphatidylinositol 4,5-bisphosphate (PIP2) is a signaling phospholipid, present in the plasma membrane. It acts as a precursor for inositide 3 phosphate, diacylglycerol.[2] PIP2 is a gating ligand for most of the ion channels. It functions as an activatory ligand for eukaryotic inward rectifier potassium (Kir) channels.[5]
- Packaging: 5 mL Clear Glass Sealed Ampule (840046P-10mg)
SAFETY INFORMATION
WGK
WGK 3
Compare Similar Items
Show Difference
description: L-α-phosphatidylinositol-4,5-bisphosphate (Brain, Porcine) (ammonium salt)
Assay: >99% (TLC)
form: powder
packaging: pkg of 1 × 1 mg (840046P-1mg)pkg of 1 × 10 mg (840046P-10mg)pkg of 1 × 25 mg (840046P-25mg)pkg of 1 × 5 mg (840046P-5mg)
manufacturer/tradename: Avanti Polar Lipids
lipid type: phosphoglycerides
shipped in: dry ice
storage temp.: −20°C
SMILES string: [H][C@@](COP(O[C@H]1[C@H](O)[C@@H](OP([O-])(O)=O)[C@H](OP(O)([O-])=O)[C@@H](O)[C@H]1O)([O-])=O)(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[NH4+].[NH4+].[NH4+]
InChI: 1S/C47H85O19P3.3H3N/c1-3-5-7-9-11-13-15-17-19-20-22-24-26-28-30-32-34-36-41(49)63-39(37-61-40(48)35-33-31-29-27-25-23-21-18-16-14-12-10-8-6-4-2)38-62-69(59,60)66-45-42(50)43(51)46(64-67(53,54)55)47(44(45)52)65-68(56,57)58;;;/h11,13,17,19,22,24,28,30,39,42-47,50-52H,3-10,12,14-16,18,20-21,23,25-27,29,31-38H2,1-2H3,(H,59,60)(H2,53,54,55)(H2,56,57,58);3*1H3/b13-11-,19-17-,24-22-,30-28-;;;/t39-,42?,43+,44?,45-,46?,47?;;;/m1.../s1
description:
L-α-phosphatidylinositol-4,5-bisphosphate (Brain, Porcine) (ammonium salt)
Assay:
>99% (TLC)
form:
powder
packaging:
pkg of 1 × 1 mg (840046P-1mg)pkg of 1 × 10 mg (840046P-10mg)pkg of 1 × 25 mg (840046P-25mg)pkg of 1 × 5 mg (840046P-5mg)
manufacturer/tradename:
Avanti Polar Lipids
lipid type:
phosphoglycerides
shipped in:
dry ice
storage temp.:
−20°C
SMILES string:
[H][C@@](COP(O[C@H]1[C@H](O)[C@@H](OP([O-])(O)=O)[C@H](OP(O)([O-])=O)[C@@H](O)[C@H]1O)([O-])=O)(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[NH4+].[NH4+].[NH4+]
InChI:
1S/C47H85O19P3.3H3N/c1-3-5-7-9-11-13-15-17-19-20-22-24-26-28-30-32-34-36-41(49)63-39(37-61-40(48)35-33-31-29-27-25-23-21-18-16-14-12-10-8-6-4-2)38-62-69(59,60)66-45-42(50)43(51)46(64-67(53,54)55)47(44(45)52)65-68(56,57)58;;;/h11,13,17,19,22,24,28,30,39,42-47,50-52H,3-10,12,14-16,18,20-21,23,25-27,29,31-38H2,1-2H3,(H,59,60)(H2,53,54,55)(H2,56,57,58);3*1H3/b13-11-,19-17-,24-22-,30-28-;;;/t39-,42?,43+,44?,45-,46?,47?;;;/m1.../s1
description: __
Assay: >99% (TLC)
form: liquid
packaging: pkg of 1 × 1 mL (840046X-10mg)pkg of 1 × 1 mL (840046X-1mg)pkg of 1 × 1 mL (840046X-5mg)pkg of 1 × 2.5 mL (840046X-25mg)
manufacturer/tradename: Avanti Polar Lipids
lipid type: phosphoglycerides
shipped in: dry ice
storage temp.: −20°C
SMILES string: [H][C@@](COP(O[C@H]1[C@H](O)[C@@H](OP([O-])(O)=O)[C@H](OP(O)([O-])=O)[C@@H](O)[C@H]1O)([O-])=O)(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[NH4+].[NH4+].[NH4+]
InChI: 1S/C47H85O19P3.3H3N/c1-3-5-7-9-11-13-15-17-19-20-22-24-26-28-30-32-34-36-41(49)63-39(37-61-40(48)35-33-31-29-27-25-23-21-18-16-14-12-10-8-6-4-2)38-62-69(59,60)66-45-42(50)43(51)46(64-67(53,54)55)47(44(45)52)65-68(56,57)58;;;/h11,13,17,19,22,24,28,30,39,42-47,50-52H,3-10,12,14-16,18,20-21,23,25-27,29,31-38H2,1-2H3,(H,59,60)(H2,53,54,55)(H2,56,57,58);3*1H3/b13-11-,19-17-,24-22-,30-28-;;;/t39-,42?,43+,44?,45-,46?,47?;;;/m1.../s1
description:
__
Assay:
>99% (TLC)
form:
liquid
packaging:
pkg of 1 × 1 mL (840046X-10mg)pkg of 1 × 1 mL (840046X-1mg)pkg of 1 × 1 mL (840046X-5mg)pkg of 1 × 2.5 mL (840046X-25mg)
manufacturer/tradename:
Avanti Polar Lipids
lipid type:
phosphoglycerides
shipped in:
dry ice
storage temp.:
−20°C
SMILES string:
[H][C@@](COP(O[C@H]1[C@H](O)[C@@H](OP([O-])(O)=O)[C@H](OP(O)([O-])=O)[C@@H](O)[C@H]1O)([O-])=O)(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[NH4+].[NH4+].[NH4+]
InChI:
1S/C47H85O19P3.3H3N/c1-3-5-7-9-11-13-15-17-19-20-22-24-26-28-30-32-34-36-41(49)63-39(37-61-40(48)35-33-31-29-27-25-23-21-18-16-14-12-10-8-6-4-2)38-62-69(59,60)66-45-42(50)43(51)46(64-67(53,54)55)47(44(45)52)65-68(56,57)58;;;/h11,13,17,19,22,24,28,30,39,42-47,50-52H,3-10,12,14-16,18,20-21,23,25-27,29,31-38H2,1-2H3,(H,59,60)(H2,53,54,55)(H2,56,57,58);3*1H3/b13-11-,19-17-,24-22-,30-28-;;;/t39-,42?,43+,44?,45-,46?,47?;;;/m1.../s1
description: L-α-phosphatidylcholine (Egg, Chicken), chloroform
Assay: >99% (TLC)
form: liquid
packaging: pkg of 1 × 2.5 mL (840051C-25mg)pkg of 2 × 20 mL (840051C-1g)pkg of 2 × 4 mL (840051C-200mg)pkg of 5 × 4 mL (840051C-500mg)
manufacturer/tradename: Avanti Polar Lipids
lipid type: phospholipidsphosphoglycerides
shipped in: dry ice
storage temp.: −20°C
SMILES string: __
InChI: 1S/C42H82NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h20-21,40H,6-19,22-39H2,1-5H3/b21-20-/t40-/m1/s1
description:
L-α-phosphatidylcholine (Egg, Chicken), chloroform
Assay:
>99% (TLC)
form:
liquid
packaging:
pkg of 1 × 2.5 mL (840051C-25mg)pkg of 2 × 20 mL (840051C-1g)pkg of 2 × 4 mL (840051C-200mg)pkg of 5 × 4 mL (840051C-500mg)
manufacturer/tradename:
Avanti Polar Lipids
lipid type:
phospholipidsphosphoglycerides
shipped in:
dry ice
storage temp.:
−20°C
SMILES string:
__
InChI:
1S/C42H82NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h20-21,40H,6-19,22-39H2,1-5H3/b21-20-/t40-/m1/s1
description: L-α-phosphatidylcholine (Egg, Chicken)
Assay: >99% (TLC)
form: powder
packaging: pkg of 1 × 1 g (840051P-1g)pkg of 2 × 100 mg (840051P-200mg)pkg of 5 × 100 mg (840051P-500mg)pkg of 1 × 25 mg (840051P-25mg)
manufacturer/tradename: Avanti Polar Lipids
lipid type: phosphoglyceridesphospholipids
shipped in: dry ice
storage temp.: −20°C
SMILES string: [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)=O
InChI: 1S/C42H82NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h20-21,40H,6-19,22-39H2,1-5H3/b21-20-/t40-/m1/s1
description:
L-α-phosphatidylcholine (Egg, Chicken)
Assay:
>99% (TLC)
form:
powder
packaging:
pkg of 1 × 1 g (840051P-1g)pkg of 2 × 100 mg (840051P-200mg)pkg of 5 × 100 mg (840051P-500mg)pkg of 1 × 25 mg (840051P-25mg)
manufacturer/tradename:
Avanti Polar Lipids
lipid type:
phosphoglyceridesphospholipids
shipped in:
dry ice
storage temp.:
−20°C
SMILES string:
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)=O
InChI:
1S/C42H82NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h20-21,40H,6-19,22-39H2,1-5H3/b21-20-/t40-/m1/s1