850185P

08:0 PI(4,5)P2

Manufacturer: Sigma Aldrich

CAS Number: 852043-37-9

Synonym(S): PIP2[4′,5′](8:0/8:0); 110665

Select a Size

Pack Size SKU Availability Price
100 μG 850185P-100-μG In Stock ₹ 12,243.08
500 μG 850185P-500-μG In Stock ₹ 48,939.83

850185P - 100 μG

₹ 12,243.08

In Stock

Quantity

1

Base Price: ₹ 12,243.08

GST (18%): ₹ 2,203.754

Total Price: ₹ 14,446.834

description

1,2-dioctanoyl-sn-glycero-3-phospho-(1′-myo-inositol-4′,5′-bisphosphate) (ammonium salt)

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 100 μg (with stopper and crimp cap (850185P-100ug))pkg of 1 × 500 μg (with stopper and crimp cap (850185P-500ug))

manufacturer/tradename

Avanti Polar Lipids

lipid type

cardiolipinsphospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](OP(O)([O-])=O)[C@H](OP([O-])(O)=O)[C@@H](O)[C@H]1O)=O)(OC(CCCCCCC)=O)COC(CCCCCCC)=O.[NH4+].[NH4+].[NH4+]

Other Options

Image Product Name Manufacturer Price Range
AH55287
852043-37-9 | 1,2-dioctanoyl-sn-glycero-3-phospho-(1'-myo-inositol-4',5'-bisphosphate) (ammonium salt)
A2B Chem --

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Description

  • General description: Although PI(4,5)P2 is a minor component of cell membranes, it plays a critical role as a substrate for a number of important signaling proteins. PI(4,5)P2 is an intermediate in the IP3/DAG pathway where it is hydrolyzed by phospholipase C to liberate the second messengers, inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG). PI(4,5)P2 is also a substrate for PI 3-kinase where it is phosphorylated to PI(3,4,5)P3, an activator of downstream signaling components such as the protein kinase AKT. The dioctanoyl derivative of PI(4,5)P2 is more water soluble than its long chain counterparts.
  • Application: 08:0 PI(4,5)P2 is suitable for use to identify its binding site in transient receptor potential vanilloid 4 (TRPV4 N) terminus.[1] It has been used in in vitro binding assay to determine the binding of G-protein coupled receptor kinases (GRKs) and β2-adrenergic receptor (β2AR).[2]
  • Packaging: 2 mL Amber Serum Vial with Stopper and Crimp Cap (850185P-100ug)

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description:
1,2-dioctanoyl-sn-glycero-3-phospho-(1′-myo-inositol-4′,5′-bisphosphate) (ammonium salt)

Assay:
>99% (TLC)

form:
powder

packaging:
pkg of 1 × 100 μg (with stopper and crimp cap (850185P-100ug))pkg of 1 × 500 μg (with stopper and crimp cap (850185P-500ug))

manufacturer/tradename:
Avanti Polar Lipids

lipid type:
cardiolipinsphospholipids

shipped in:
dry ice

storage temp.:
−20°C

SMILES string:
[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](OP(O)([O-])=O)[C@H](OP([O-])(O)=O)[C@@H](O)[C@H]1O)=O)(OC(CCCCCCC)=O)COC(CCCCCCC)=O.[NH4+].[NH4+].[NH4+]

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description:
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Assay:
>99% (TLC)

form:
powder

packaging:
pkg of 1 × 100 μg (with stopper and crimp cap (850186P-100ug))pkg of 1 × 500 μg (with stopper and crimp cap (850186P-500ug))

manufacturer/tradename:
Avanti Polar Lipids 850186P

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shipped in:
dry ice

storage temp.:
−20°C

SMILES string:
[H][C@@](COP(O[C@H]1[C@H](O)[C@@H](OP([O-])(O)=O)[C@H](OP(O)([O-])=O)[C@@H](OP(O)([O-])=O)[C@H]1O)([O-])=O)(OC(CCCCCCC)=O)COC(CCCCCCC)=O.[NH4+].[NH4+].[NH4+].[NH4+]

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packaging:
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lipid type:
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shipped in:
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storage temp.:
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OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=C(Br)C(=O)NC2=O

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Sigma Aldrich

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description:
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Assay:
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pkg of 1 × 100 μg (with stopper and crimp cap (850187P-100ug))pkg of 1 × 500 μg (with stopper and crimp cap (850187P-500ug))

manufacturer/tradename:
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shipped in:
dry ice

storage temp.:
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SMILES string:
[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](OP([O-])(O)=O)[C@H]1O)=O)(OC(CCCCCCC)=O)COC(CCCCCCC)=O.[NH4+].[NH4+]