860463P

N-C16-desoxymethylsphinganine

Manufacturer: Sigma Aldrich

CAS Number: 1246298-42-9

Synonym(S): N-palmitoyl-1-desoxymethylsphinganine (m17:0/16:0)

Select a Size

Pack Size SKU Availability Price
1 MG 860463P-1-MG In Stock ₹ 43,559.80

860463P - 1 MG

₹ 43,559.80

In Stock

Quantity

1

Base Price: ₹ 43,559.80

GST (18%): ₹ 7,840.764

Total Price: ₹ 51,400.564

form

powder

packaging

pkg of 1 × 1 mg (860463P-1mg)pkg of 1 × 5 mg (860463P-5mg)

manufacturer/tradename

Avanti Polar Lipids 860463P

lipid type

sphingolipidsbioactive lipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@](CCCCCCCCCCCCCCC)(O)CNC(CCCCCCCCCCCCCCC)=O

Description

  • General description: N-C16-desoxymethylsphinganine is the N-acylated form of 1-desoxymethylsphinganine,[1] a potent inhibitor of sphingolipid metabolism. Ceramide synthases (CerS) catalyzes the acylation of sphingoid bases using fatty acyl-CoA and its inhibition results in decrease of N-acylsphinganines (dihydroceramides) levels and accumulation of sphinganine. Dihydroceramides (DHCer) are intermediates of ceramide biosynthesis.[2]
  • Biochem/physiol Actions: Dihydroceramides are also used for dihydrosphingolipids synthesis. Treatment of MCF7 cancer cells with fenretinide alters sphingolipid metabolism.[2]
  • Packaging: 5 mL Amber Glass Screw Cap Vial (860463P-1mg)

SAFETY INFORMATION

WGK

WGK 3

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form:
powder

packaging:
pkg of 1 × 1 mg (860463P-1mg)pkg of 1 × 5 mg (860463P-5mg)

manufacturer/tradename:
Avanti Polar Lipids 860463P

lipid type:
sphingolipidsbioactive lipids

shipped in:
dry ice

storage temp.:
−20°C

SMILES string:
[H][C@](CCCCCCCCCCCCCCC)(O)CNC(CCCCCCCCCCCCCCC)=O

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powder

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pkg of 1 × 1 mg (860464P-1mg)

manufacturer/tradename:
Avanti Polar Lipids 860464P

lipid type:
sphingolipidsbioactive lipids

shipped in:
dry ice

storage temp.:
−20°C

SMILES string:
C[C@]([H])(NC(CCCCCCCCCCCCC/C=C\CCCCCCCC)=O)[C@]([H])(O)CCCCCCCCCCCCCCC

Img

Sigma Aldrich

860465P

--


form:
powder

packaging:
pkg of 1 × 1 mg (860465P-1mg)pkg of 1 × 5 mg (860465P-5mg)

manufacturer/tradename:
Avanti Polar Lipids 860465P

lipid type:
bioactive lipidssphingolipids

shipped in:
dry ice

storage temp.:
−20°C

SMILES string:
[H][C@](CCCCCCCCCCCCCCC)(O)CNC(CCCCCCCCCCCCC/C=C/CCCCCCCC)=O

Img

Sigma Aldrich

860466P

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form:
powder

packaging:
pkg of 1 × 1 mg (860466P-1mg)

manufacturer/tradename:
Avanti Polar Lipids 860466P

lipid type:
sphingolipidsbioactive lipids

shipped in:
dry ice

storage temp.:
−20°C

SMILES string:
[H][C@](/C=C/CCCCCCCCCCCCC)(O)CNC(CCCCCCCCCCC)=O