860508P

C8 Ceramide (d18:1/8:0)

Manufacturer: Sigma Aldrich

CAS Number: 74713-59-0

Synonym(S): N-octanoyl-D-erythro-sphingosine

Select a Size

Pack Size SKU Availability Price
5 MG 860508P-5-MG In Stock ₹ 12,557.00

860508P - 5 MG

₹ 12,557.00

In Stock

Quantity

1

Base Price: ₹ 12,557.00

GST (18%): ₹ 2,260.26

Total Price: ₹ 14,817.26

form

powder

packaging

pkg of 1 × 5 mg (860508P-5mg)

manufacturer/tradename

Avanti Polar Lipids 860508P

lipid type

sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

OC[C@]([H])(NC(CCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC

InChI

1S/C26H51NO3/c1-3-5-7-9-10-11-12-13-14-15-16-18-19-21-25(29)24(23-28)27-26(30)22-20-17-8-6-4-2/h19,21,24-25,28-29H,3-18,20,22-23H2,1-2H3,(H,27,30)/b21-19+/t24-,25+/m0/s1

InChI key

APDLCSPGWPLYEQ-WRBRXSDHSA-N

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Description

  • General description: C8 Ceramide is a short chain ceramide and is cell permeable.[1]
  • Application: C8 Ceramide (d18:1/8:0) has been used as an internal ceramide standard in electrospray ionization.[2] It has also been used as a substrate for ceramide kinase activity assay.[3] It is suitable for use as a substrate for galactocerebrosidase.[4]
  • Biochem/physiol Actions: C8 Ceramide has anti-tumor functionality.[1] Synthetic liposomal C8 ceramide inhibits hepatocellular carcinoma (HCC).[1] Addition of exogenous C8 ceramide causes necrosis in hepatocytes by decreasing ATP levels and impairing mitochondrial functionality.[5] C8 ceramide inhibition of serine palmitoyl transferase halts de novo sphingolipid biosynthesis.[6] It also acts as chemotherapeutic agent by increasing the reactive oxygen species in lung cancer cells.[7]
  • Packaging: 5 mL Amber Glass Screw Cap Vial (860508P-5mg)

Compare Similar Items

Show Difference

Img

Sigma Aldrich

860508P

--


form:
powder

packaging:
pkg of 1 × 5 mg (860508P-5mg)

manufacturer/tradename:
Avanti Polar Lipids 860508P

lipid type:
sphingolipids

shipped in:
dry ice

storage temp.:
−20°C

SMILES string:
OC[C@]([H])(NC(CCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC

InChI:
1S/C26H51NO3/c1-3-5-7-9-10-11-12-13-14-15-16-18-19-21-25(29)24(23-28)27-26(30)22-20-17-8-6-4-2/h19,21,24-25,28-29H,3-18,20,22-23H2,1-2H3,(H,27,30)/b21-19+/t24-,25+/m0/s1

InChI key:
APDLCSPGWPLYEQ-WRBRXSDHSA-N

Img

Sigma Aldrich

860510P

--


form:
powder

packaging:
pkg of 1 × 5 mg (860510P-5mg)

manufacturer/tradename:
Avanti Polar Lipids 860510P

lipid type:
sphingolipids

shipped in:
dry ice

storage temp.:
−20°C

SMILES string:
OC[C@]([H])(NC(CCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC

InChI:
1S/C28H55NO3/c1-3-5-7-9-11-12-13-14-15-16-18-19-21-23-27(31)26(25-30)29-28(32)24-22-20-17-10-8-6-4-2/h21,23,26-27,30-31H,3-20,22,24-25H2,1-2H3,(H,29,32)/b23-21+/t26-,27+/m0/s1

InChI key:
FDWVAQFAMZLCAX-NBNLIBPQSA-N

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Sigma Aldrich

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form:
powder

packaging:
pkg of 1 × 10 mg (860517P-10mg)pkg of 1 × 25 mg (860517P-25mg)pkg of 1 × 5 mg (860517P-5mg)

manufacturer/tradename:
Avanti Polar Lipids

lipid type:
sphingolipids

shipped in:
dry ice

storage temp.:
−20°C

SMILES string:
OC[C@]([H])(NC(CCCCCCCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC

InChI:
1S/C35H69NO3/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-35(39)36-33(32-37)34(38)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h28,30,33-34,37-38H,3-27,29,31-32H2,1-2H3,(H,36,39)/b30-28+/t33-,34+/m0/s1

InChI key:
ICWGMOFDULMCFL-QKSCFGQVSA-N

Img

Sigma Aldrich

860518P

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form:
powder

packaging:
pkg of 1 × 10 mg (860518P-10mg)pkg of 1 × 5 mg (860518P-5mg)

manufacturer/tradename:
Avanti Polar Lipids

lipid type:
sphingolipids

shipped in:
dry ice

storage temp.:
−20°C

SMILES string:
OC[C@]([H])(NC(CCCCCCCCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC

InChI:
1S/C36H71NO3/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-36(40)37-34(33-38)35(39)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2/h29,31,34-35,38-39H,3-28,30,32-33H2,1-2H3,(H,37,40)/b31-29+/t34-,35+/m0/s1

InChI key:
VODZWWMEJITOND-NXCSZAMKSA-N