A0752

Adenosine 5′-diphosphoribose sodium salt

≥93%

Manufacturer: Sigma Aldrich

CAS Number: 68414-18-6

Synonym(S): ADPR, ADP-Ribose

Select a Size

Pack Size SKU Availability Price
25 MG A0752-25-MG In Stock ₹ 9,655.90
100 MG A0752-100-MG In Stock ₹ 27,019.20
500 MG A0752-500-MG In Stock ₹ 1,14,441.90

A0752 - 25 MG

₹ 9,655.90

In Stock

Quantity

1

Base Price: ₹ 9,655.90

GST (18%): ₹ 1,738.062

Total Price: ₹ 11,393.962

biological source

yeast (candida utilis)

Quality Level

200

Assay

≥93%

form

powder

storage temp.

−20°C

SMILES string

[Na].Nc1ncnc2n(cnc12)C3OC(COP(O)(=O)OP(O)(=O)OCC(O)C(O)C(O)C=O)C(O)C3O

InChI

1S/C15H23N5O14P2.Na.H/c16-13-9-14(18-4-17-13)20(5-19-9)15-12(26)11(25)8(33-15)3-32-36(29,30)34-35(27,28)31-2-7(23)10(24)6(22)1-21;;/h1,4-8,10-12,15,22-26H,2-3H2,(H,27,28)(H,29,30)(H2,16,17,18);;

InChI key

NWPVXDZLQTURKI-UHFFFAOYSA-N

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Description

  • Application: 5′-Deoxy-5′-(methylthio)adenosine has been used:to give a range of nicotinamide adenine dinucleotide (NADH) oxidation rates for the respiratory complex (CI/CIII/CIV)CI/alternative(AOX) pathway[1] to measure poly(ADP-ribose) glycohydrolaseactivity[2]poly(ADP-ribose) (PAR) binding competition assay[3]oxidase (AOX) pathway[1] to measure poly(ADP-ribose) glycohydrolase activity[2]poly(ADP-ribose) (PAR) binding competition assay[3]
  • Biochem/physiol Actions: Adenosine5′-diphosphoribose (ADP-Ribose) is used as the basic building block used as a substrate in the formation of poly(ADP-ribose) by members of the poly(ADP-ribose) polymerase (PARP) family. Poly(ADP-ribose) formation and degradation are important components of DNA repair and apoptosis signaling. ADP-Ribose initiates the transient receptor potential subfamily melastatin, type2 (TRPM2), a Na+, Ca2+, and K+ cation channel.[4]

SAFETY INFORMATION

Pictograms

GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Precautionary Statements

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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SMILES string:
[Na].Nc1ncnc2n(cnc12)C3OC(COP(O)(=O)OP(O)(=O)OCC(O)C(O)C(O)C=O)C(O)C3O

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