A9730

Adefovir dipivoxil

Manufacturer: Sigma Aldrich

CAS Number: 142340-99-6

Synonym(S): 9-(2[bis(Pivaloyloxymethoxy)phosphorylmethoxy]ethyl)adenine

Select a Size

Pack Size SKU Availability Price
50 MG A9730-50-MG In Stock ₹ 15,162.60
100 MG A9730-100-MG In Stock ₹ 30,880.20

A9730 - 50 MG

₹ 15,162.60

In Stock

Quantity

1

Base Price: ₹ 15,162.60

GST (18%): ₹ 2,729.268

Total Price: ₹ 17,891.868

biological source

synthetic

Quality Level

100

Assay

≥98% (HPLC)

form

solid

solubility

ethanol: 50 mg/mL

antibiotic activity spectrum

viruses

Mode of action

enzyme | inhibits

storage temp.

−20°C

SMILES string

CC(C)(C)C(=O)OCOP(=O)(COCCn1cnc2c(N)ncnc12)OCOC(=O)C(C)(C)C

InChI

1S/C20H32N5O8P/c1-19(2,3)17(26)30-11-32-34(28,33-12-31-18(27)20(4,5)6)13-29-8-7-25-10-24-14-15(21)22-9-23-16(14)25/h9-10H,7-8,11-13H2,1-6H3,(H2,21,22,23)

Other Options

Image Product Name Manufacturer Price Range
50-175-7717
Sigma Aldrich Fine Chemicals Biosciences Adefovir dipivoxil | 142340-99-6 | MFCD00869897 | 50MG
Sigma Aldrich Fine Chemicals Biosciences ₹ 20,648.19
50-503-1
Selleck Chemical LLC Adefovir Dipivoxil 100mg 142340-99-6
Selleck Chemical LLC ₹ 12,320.64
AD71533
142340-99-6 | Adefovir Dipivoxil
A2B Chem ₹ 855.60 - ₹ 16,598.64

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Description

  • Biochem/physiol Actions: Adefovir is an antiviral acyclic nucleoside phosphonate (ANP) analog that works by blocking reverse transcriptase.[1] It is an inhibitor of duck hepatitis B virus (DHBV) replication that inhibits covalently closed circular DNA (CCC DNA) amplification.[2] Cytotxicity is induced by Human Renal Organic Anion Transporter 1 (hOAT1).[3] Adefovir is an Inhibitor of edema factor (EF)-induced cAMP accumulation and changes in cytokine production in mouse primary macrophages [4].
  • Other Notes: Keep container tightly closed in a dry and well-ventilated place.

SAFETY INFORMATION

Pictograms

GHS07

Signal Word

Warning

Hazard Statements

H302 + H312 + H332

Precautionary Statements

P261 - P264 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312

Hazard Classifications

Acute Tox. 4 Oral

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Quality Level:
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Assay:
≥98% (HPLC)

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solid

solubility:
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antibiotic activity spectrum:
viruses

Mode of action:
enzyme | inhibits

storage temp.:
−20°C

SMILES string:
CC(C)(C)C(=O)OCOP(=O)(COCCn1cnc2c(N)ncnc12)OCOC(=O)C(C)(C)C

InChI:
1S/C20H32N5O8P/c1-19(2,3)17(26)30-11-32-34(28,33-12-31-18(27)20(4,5)6)13-29-8-7-25-10-24-14-15(21)22-9-23-16(14)25/h9-10H,7-8,11-13H2,1-6H3,(H2,21,22,23)

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