Description

• General description: Ascorbic acid is also referred to as Vitamin C.[1] It contains a six-carbon lactone produced by plants and some animal species but not by humans and other primates. Vitamin C is a water-soluble vitamin.[2] Vitamin C is a part of citrus fruits, such as Indian gooseberry, broccoli, strawberries, brussels sprouts.[2] L-ascorbic acid is the biologically active form of ascorbic acid. It is unstable and hydrophilic.[1] Ascorbic acid carries a neutral charge, which gets converted to ascorbate by protonation.[3]
• Application: L-Ascorbic acid has been used to induce osteoblast differentiation from primary bone marrow cultures.[4]It has been used for the differentiation of hCMPCs (human cardiomyocyte progenitor cells) into cardiomyocytes.[5] It has been used to measure the mitochondrial electron transport chain (complex IV) activity.[6]
• Biochem/physiol Actions: L-Ascorbic acid plays a role in production of neurotransmitters, carnitine and collagen synthesis.[2] Ascorbic acid functions as an enzymatic cofactor for multiple enzymes, serving as an electron donor for monooxygenases and dioxygenases. Ascorbic acid also functions as a powerful antioxidant, particularly in regards to reactive oxygen species.[7] Vitamin C exhibits anti-oxidant properties. Vitamin C is implicated in conferring protection against photoaging and anti-aging.[1] Deficiency of vitamin C is associated with scurvy, bleeding gums, poor wound healing, anemia and muscle degeneration.[2]
• Caution: May darken in storage.
• Other Notes: 2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research