Cardiolipin solution from bovine heart

Description

• General description: Cardiolipin (CL) is a complex lipid with a dimeric structure. It has four acyl chains and two phosphatidyl moieties. Its phosphatidyl moieties are linked to the glycerol backbone. Around 15-20 percent of the inner mitochondrial membrane accounts for cardiolipin.
• Application: Cardiolipin solution from bovine heart has been used:for coating Corning 96-well enzyme immunoassay/radioimmunoassay (EIA/RIA) plate to perform enzyme-linked immunosorbent assay (ELISA)-based cardiolipin binding assayin lipid analysis along with phosphatidylglycerol (PG) to comigrate the radiolabeled lipids to identify PG and cardiolipin (CL)in coating ELISA plates for antiphospholipid antibodies (aPL) assays
• Biochem/physiol Actions: Cardiolipin (CL) plays a key role in mitochondrial biogenesis, fusion and fission, respiration, and protein import. It participates in the cellular processes outside of the mitochondria like cell wall biogenesis, aging, vacuole homeostasis, the cell cycle, and apoptosis. CL is also involved in heart function, autophagy/mitophagy, and the protein kinase C (PKC) pathway.
• Features and Benefits: High-quality molecule suitable for mulitple research applicationsCommonly employed in Metabolomics and Biochemical studies
• Other Notes: >80% polyunsaturated fatty acid content, primarily linoleic acid.
• Physical form: Approximately 5 mg/ml in ethanol.