C6880

D-Cycloserine

Manufacturer: Sigma Aldrich

CAS Number: 68-41-7

Synonym(S): (R)-4-Amino-3-isoxazolidone, 4-Amino-3-isoxazolidinone

Select a Size

Pack Size SKU Availability Price
1 G C6880-1-G In Stock ₹ 7,739.88
5 G C6880-5-G In Stock ₹ 27,246.53

C6880 - 1 G

₹ 7,739.88

In Stock

Quantity

1

Base Price: ₹ 7,739.88

GST (18%): ₹ 1,393.178

Total Price: ₹ 9,133.058

form

powder

Quality Level

200

mp

147 °C (dec.) (lit.)

antibiotic activity spectrum

Gram-negative bacteriamycobacteria

Mode of action

cell wall synthesis | interferes

storage temp.

−20°C

SMILES string

N[C@@H]1CONC1=O

InChI

1S/C3H6N2O2/c4-2-1-7-5-3(2)6/h2H,1,4H2,(H,5,6)/t2-/m1/s1

InChI key

DYDCUQKUCUHJBH-UWTATZPHSA-N

Gene Information

human ... GRIN1(2902) , GRIN2A(2903) , GRIN2B(2904) , GRIN2C(2905) , GRIN2D(2906) , GRIN3A(116443) , GRIN3B(116444) , GRINA(2907) mouse ... GRIN1(14810) , GRIN2A(14811) , GRIN2B(14812) , GRIN2C(14813) , GRIN2D(14814) , GRIN3A(242443) , GRIN3B(170483) , GRINA(66168) rat ... GRIN1(24408) , GRIN2A(24409) , GRIN2B(24410) , GRIN2C(24411) , GRIN2D(24412) , GRIN3A(191573) , GRIN3B(170796) , GRINA(266668)

Other Options

Image Product Name Manufacturer Price Range
50-184-4372
Sigma Aldrich Fine Chemicals Biosciences D-Cycloserine | 68-41-7 | MFCD00005353 | 1G
Sigma Aldrich Fine Chemicals Biosciences ₹ 9,894.16
50-208-2349
Medchemexpress LLC HY-B0030 500mg Medchemexpress, D-Cycloserine CAS:68-41-7 Purity:>98%
Medchemexpress LLC ₹ 6,288.66
50-491-934
Chem-Impex International, Inc. D-Cycloserine | 68-41-7 | MFCD00005353 | 5G
Chem-Impex International, Inc. ₹ 4,388.37
50-496-779
Chem-Impex International, Inc. D-Cycloserine, synthetic | 68-41-7 | MFCD00005353 | 1G
Chem-Impex International, Inc. ₹ 2,887.65
PHR1765
Cycloserine
Supelco ₹ 11,647.70
30020
D-Cycloserine
Sigma Aldrich ₹ 6,743.98 - ₹ 91,666.10
C6880
D-Cycloserine
Sigma Aldrich ₹ 7,739.88 - ₹ 27,246.53
30020
D-Cycloserine
Sigma Aldrich ₹ 6,743.98 - ₹ 91,666.10
CS-2395
D-Cycloserine
ChemScene ₹ 427.80 - ₹ 41,325.48
AI54871
68-41-7 | (4R)-4-amino-1,2-oxazolidin-3-one
A2B Chem ₹ 1,368.96 - ₹ 39,870.96

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Description

  • General description: Chemical structure: amino acid derivatives
  • Application: D-Cycloserine (DCS) has been used:to study its effect on partner preference in Prairie Voles[1]to study its effect on grooming behaviour of rats[2]to determine its minimum inhibitory concentration (MIC) on 48 multidrug resistant tuberculosis (MDR-TB) isolates using the broth microdilution method[3]to study its effect on mouse model of autism, using behavioural assays[4]
  • Biochem/physiol Actions: D-cycloserine (DCS) was initially known as a tuberculostatic agent. It acts as a glutamatergic partial N-methyl-D-aspartate (NMDA) agonist. It binds at the glycine-binding site of the NMDA receptor and enable the opening of the NMDA channel.[5] DCS has a an ability to improve various forms of learning and memory hence, this drug might be effective for improving social memory and cognition.[1] DCS can be used as a potential therapeutic for psychiatric disorders such as phobias, social anxiety, obsessive-compulsive disorder, and posttraumatic stress disorder.[6]

SAFETY INFORMATION

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Show Difference

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Sigma Aldrich

C6880

--


form:
powder

Quality Level:
200

mp:
147 °C (dec.) (lit.)

antibiotic activity spectrum:
Gram-negative bacteriamycobacteria

Mode of action:
cell wall synthesis | interferes

storage temp.:
−20°C

SMILES string:
N[C@@H]1CONC1=O

InChI:
1S/C3H6N2O2/c4-2-1-7-5-3(2)6/h2H,1,4H2,(H,5,6)/t2-/m1/s1

InChI key:
DYDCUQKUCUHJBH-UWTATZPHSA-N

Gene Information:
human ... GRIN1(2902) , GRIN2A(2903) , GRIN2B(2904) , GRIN2C(2905) , GRIN2D(2906) , GRIN3A(116443) , GRIN3B(116444) , GRINA(2907) mouse ... GRIN1(14810) , GRIN2A(14811) , GRIN2B(14812) , GRIN2C(14813) , GRIN2D(14814) , GRIN3A(242443) , GRIN3B(170483) , GRINA(66168) rat ... GRIN1(24408) , GRIN2A(24409) , GRIN2B(24410) , GRIN2C(24411) , GRIN2D(24412) , GRIN3A(191573) , GRIN3B(170796) , GRINA(266668)

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−20°C

SMILES string:
__

InChI:
__

InChI key:
__

Gene Information:
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antibiotic activity spectrum:
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SMILES string:
OC[C@H]1O[C@H](C[C@@H]1O)N2C=C(Cl)C(=O)NC2=O

InChI:
1S/C9H11ClN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s1

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NJCXGFKPQSFZIB-RRKCRQDMSA-N

Gene Information:
__

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Sigma Aldrich

C6895

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form:
powder or crystals

Quality Level:
200

mp:
__

antibiotic activity spectrum:
Gram-negative bacteriaGram-positive bacteria

Mode of action:
cell wall synthesis | interferes

storage temp.:
__

SMILES string:
N[C@@H](C(=O)N[C@H]1[C@H]2SCC(Cl)=C(N2C1=O)C(O)=O)c3ccccc3

InChI:
1S/C15H14ClN3O4S/c16-8-6-24-14-10(13(21)19(14)11(8)15(22)23)18-12(20)9(17)7-4-2-1-3-5-7/h1-5,9-10,14H,6,17H2,(H,18,20)(H,22,23)/t9-,10-,14-/m1/s1

InChI key:
QYIYFLOTGYLRGG-GPCCPHFNSA-N

Gene Information:
__