E3768

(−)-Epigallocatechin

≥95% (HPLC), from green tea

Manufacturer: Sigma Aldrich

CAS Number: 970-74-1

Synonym(S): (−)-cis-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol, (−)-cis-3,3′,4′,5,5′,7-Hexahydroxyflavane

Select a Size

Pack Size SKU Availability Price
5 MG E3768-5-MG In Stock ₹ 14,190.00

E3768 - 5 MG

₹ 14,190.00

In Stock

Quantity

1

Base Price: ₹ 14,190.00

GST (18%): ₹ 2,554.20

Total Price: ₹ 16,744.20

biological source

green tea

Quality Level

200

Assay

≥95% (HPLC)

application(s)

metabolomicsvitamins, nutraceuticals, and natural products

storage temp.

2-8°C

SMILES string

O[C@@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3cc(O)c(O)c(O)c3

InChI

1S/C15H14O7/c16-7-3-9(17)8-5-12(20)15(22-13(8)4-7)6-1-10(18)14(21)11(19)2-6/h1-4,12,15-21H,5H2/t12-,15-/m1/s1

InChI key

XMOCLSLCDHWDHP-IUODEOHRSA-N

Gene Information

human ... CYP1A2(1544)

Other Options

Image Product Name Manufacturer Price Range
11-101-5985
(-)-Epigallocatechin, ≥90% (HPLC), MilliporeSigma™ Supelco™
MilliporeSigma Supelco ₹ 11,944.18
50-178-7619
Sigma Aldrich Fine Chemicals Biosciences (-)-Epigallocatechin >=95% (HPLC), from green tea | 970-74-1 | MFCD00075939 | 5MG
Sigma Aldrich Fine Chemicals Biosciences ₹ 14,569.16
50-164-5415
Indofine Chemical (-)-EPIGALLOCATECHIN with HPLC, Herbal Standards, 970-74-1, >98% by HPLC, 10 mg
Indofine Chemical ₹ 17,218.95
08108
(−)-Epigallocatechin
Supelco ₹ 11,626.05
PHL89655
(−)-Epigallocatechin
Sigma Aldrich ₹ 52,696.10
03960590
Epigallocatechin
Sigma Aldrich ₹ 53,735.30
CS-3762
(-)-Epigallocatechin
ChemScene ₹ 2,994.60 - ₹ 23,956.80

Description

  • General description: (−)-Epigallocatechin is one of the main catechin compounds found in green tea and the most abundant one (~20%), with antioxidant properties.[1][2]
  • Application: (−)-Epigallocatechin (EGC) has been used:as a reference standard in high-performance liquid chromatography (HPLC) analysis[3]to analyze its inhibitory effect on α-amylase and α-glucosidase activity to control postprandial hyperglycemia in Diabetes mellitus[4]in cell viability assays to check its efficacy and protection against ferroptosis and iron toxicity in murine pancreatic β-cells[5]to evaluate its potential anti-inflammatory effects on long-term acute and chronic Pristen-induced arthritis[6]to treat pregnant and nursing mice, on in vitro angiogenesis, proliferation, and movement of endothelial cells[7]to evaluate its effect on pregnant and nursing mice spleen based on the number and localization of CD4+ (cluster of differentiation 4) and CD8+ cluster of differentiation 8) cells[8]
  • Biochem/physiol Actions: (−)-Epigallocatechin (EGC) has proven to be an anti-cancer agent by its inhibitory effects on heregulin-b1 (HRG)-induced migration/invasion in MCF-7 human breast carcinoma cells.[9] It has also shown strong antiviral activity against the herpes simplex virus.[10]

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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≥95% (HPLC), from green tea...


biological source:
green tea

Quality Level:
200

Assay:
≥95% (HPLC)

application(s):
metabolomicsvitamins, nutraceuticals, and natural products

storage temp.:
2-8°C

SMILES string:
O[C@@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3cc(O)c(O)c(O)c3

InChI:
1S/C15H14O7/c16-7-3-9(17)8-5-12(20)15(22-13(8)4-7)6-1-10(18)14(21)11(19)2-6/h1-4,12,15-21H,5H2/t12-,15-/m1/s1

InChI key:
XMOCLSLCDHWDHP-IUODEOHRSA-N

Gene Information:
human ... CYP1A2(1544)

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OC(=O)CN(CCOCCOCCN(CC(O)=O)CC(O)=O)CC(O)=O

InChI:
1S/C14H24N2O10/c17-11(18)7-15(8-12(19)20)1-3-25-5-6-26-4-2-16(9-13(21)22)10-14(23)24/h1-10H2,(H,17,18)(H,19,20)(H,21,22)(H,23,24)

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E3893

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biological source:
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≥98% (HPLC)

application(s):
metabolomicsvitamins, nutraceuticals, and natural products

storage temp.:
2-8°C

SMILES string:
Oc1cc(O)c2C[C@@H](OC(=O)c3cc(O)c(O)c(O)c3)[C@H](Oc2c1)c4ccc(O)c(O)c4

InChI:
1S/C22H18O10/c23-11-6-14(25)12-8-19(32-22(30)10-4-16(27)20(29)17(28)5-10)21(31-18(12)7-11)9-1-2-13(24)15(26)3-9/h1-7,19,21,23-29H,8H2/t19-,21-/m1/s1

InChI key:
LSHVYAFMTMFKBA-TZIWHRDSSA-N

Gene Information:
human ... CYP1A2(1544)