G5642

Monosialoganglioside GM3 from canine blood

≥98%, lyophilized powder

Manufacturer: Sigma Aldrich

CAS Number: 54827-14-4

Select a Size

Pack Size SKU Availability Price
0.5 MG G5642-0.5-MG In Stock ₹ 49,405.30
1 MG G5642-1-MG In Stock ₹ 92,456.33

G5642 - 0.5 MG

₹ 49,405.30

In Stock

Quantity

1

Base Price: ₹ 49,405.30

GST (18%): ₹ 8,892.954

Total Price: ₹ 58,298.254

Quality Level

200

Assay

≥98%

form

lyophilized powder

solubility

chloroform/methanol/water (9.5:9.5:1): 20 mg/mL, clear, colorless to light yellow

storage temp.

−20°C

Other Options

Image Product Name Manufacturer Price Range
AW54333
54827-14-4 | Ganglioside GM3
A2B Chem ₹ 20,363.28

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Description

  • General description: Gangliosides are major constituents of neuronal cell membranes and endoplasmic reticulum. They contain a sialated polysaccharide chain linked to ceramide through a β-glycosidic linkage. For classification of gangliosides see Svennerholm, L., et al. (eds.), Structure and Function of Gangliosides, New York, Plenum, 1980.
  • Application: Monosialoganglioside GM3 from canine blood has been used as a reference standard in high-performance thin-layer chromatography (HPTLC) to analyze ganglioside signatures of prostate cancer (CaP) cells.[1][2] It has also been used to determine ganglioside-binding profiles of methylotrophic yeast (Pichia pastoris) secreted cholera toxin B subunit (PpCTB) by enzyme-linked immunosorbent assay (ELISA).[3]
  • Biochem/physiol Actions: Monosialoganglioside GM3 has a potential role in cancer development and progression. Increased expression of GM3 has been observed in various types of cancer. Hence, it is used as a tumor-associated carbohydrate antigen during cancer vaccine development.[4]
  • Analysis Note: The product is soluble at 20 mg/mL in a 1:1 mixture of chloroform and ethanol with 5% water. The resulting solution is colorless

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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