Hygromycin B solution from Streptomyces hygroscopicus
≥60% (HPLC), 45-60 mg/mL in H2O
Manufacturer: Sigma Aldrich
CAS Number: 31282-04-9
Synonym(S): Hygromycin B, Hygrovetine
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 500 MG | H0654-500-MG | In Stock | ₹ 23,890.78 |
| 250 MG | H0654-250-MG | In Stock | ₹ 24,529.45 |
| 1 G | H0654-1-G | In Stock | ₹ 39,576.20 |
H0654 - 500 MG
In Stock
Quantity
1
Base Price: ₹ 23,890.78
GST (18%): ₹ 4,300.34
Total Price: ₹ 28,191.12
biological source
Streptomyces hygroscopicus
Quality Level
200
sterility
0.22 μm filtered
concentration
≥60% (HPLC)45-60 mg/mL in H2O
color
brown-yellowlight orange to dark orangelight yellow to dark yellow
antibiotic activity spectrum
viruses
Mode of action
protein synthesis | interferes
storage temp.
2-8°C
SMILES string
CN[C@H]1C[C@@H](N)[C@H](O)[C@@H](O[C@@H]2O[C@H](CO)[C@H](O)[C@@H]3OC4(O[C@H]([C@H](N)CO)[C@H](O)[C@H](O)[C@H]4O)O[C@H]23)[C@@H]1O
InChI
1S/C20H37N3O13/c1-23-7-2-5(21)9(26)15(10(7)27)33-19-17-16(11(28)8(4-25)32-19)35-20(36-17)18(31)13(30)12(29)14(34-20)6(22)3-24/h5-19,23-31H,2-4,21-22H2,1H3/t5-,6-,7+,8-,9+,10-,11+,12-,13+,14-,15-,16+,17+,18-,19+,20+/m1/s1
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Hygromycin B from Streptomyces hygroscopicus | Sigma Aldrich | ₹ 7,783.18 - ₹ 24,551.10 | |
| | Hygromycin B from Streptomyces hygroscopicus | Sigma Aldrich | ₹ 8,497.63 - ₹ 62,211.28 | |
| | Hygromycin B from Streptomyces hygroscopicus | Sigma Aldrich | ₹ 5,629.00 - ₹ 68,154.20 | |
| | Hygromycin B solution from Streptomyces hygroscopicus | Sigma Aldrich | ₹ 22,700.03 - ₹ 72,960.50 | |
| | Hygromycin B | Sigma Aldrich | ₹ 34,650.83 |
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Description
- General description: Chemical structure: aminoglycoside
- Application: Hygromycin B is an aminoglycoside antibiotic isolated from Streptomyces hygroscopicus. It has been used to study protein synthesis at the level of the 70S ribosome translocation and mRNA template misreading, as an antiviral agent by selectively penetrating cells rendered permeable by virus infection and inhibiting translation, and as a selection agent for hygromycin resistance gene transformed cells. It is recommended for use as a selection agent at 100-800 μg/mL, specifically at 100 μg/mL for prokaryotes, 200 μg/mL for lower eukaryotes and 150-400 μg/mL for higher eukaryotes.
- Biochem/physiol Actions: Mode of action: The product acts by inhibiting protein synthesis by inducing the misreading of the m-RNA template in the prokaryote, with the potency to inhibit translation. Antimicrobial Spectrum: Hygromycin B acts against bacteria, fungi and higher eukaryotic cells.
- Caution: Hygromycin B products should be stored as supplied at 2-8°C, and the dry solid is stable for at least 5 years if stored at 2-8°C. It is stable at 37°C for 30 days.
- Preparation Note: This product is a solution that comes =60% (HPAE) and 45-60 mg/mL in H2O.
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
P260 - P264 - P270 - P280 - P302 + P352 + P312 - P304 + P340 + P310
Hazard Classifications
Acute Tox. 1 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral
WGK
WGK 3
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Compare Similar Items
Show Difference
biological source: Streptomyces hygroscopicus
Quality Level: 200
sterility: 0.22 μm filtered
concentration: ≥60% (HPLC)45-60 mg/mL in H2O
color: brown-yellowlight orange to dark orangelight yellow to dark yellow
antibiotic activity spectrum: viruses
Mode of action: protein synthesis | interferes
storage temp.: 2-8°C
SMILES string: CN[C@H]1C[C@@H](N)[C@H](O)[C@@H](O[C@@H]2O[C@H](CO)[C@H](O)[C@@H]3OC4(O[C@H]([C@H](N)CO)[C@H](O)[C@H](O)[C@H]4O)O[C@H]23)[C@@H]1O
InChI: 1S/C20H37N3O13/c1-23-7-2-5(21)9(26)15(10(7)27)33-19-17-16(11(28)8(4-25)32-19)35-20(36-17)18(31)13(30)12(29)14(34-20)6(22)3-24/h5-19,23-31H,2-4,21-22H2,1H3/t5-,6-,7+,8-,9+,10-,11+,12-,13+,14-,15-,16+,17+,18-,19+,20+/m1/s1
biological source: __
Quality Level: __
sterility: __
concentration: __
color: __
antibiotic activity spectrum: __
Mode of action: __
storage temp.: 2-8°C
SMILES string: O.Cl.N[C@@H](Cc1c[nH]cn1)C(O)=O
InChI: 1S/C6H9N3O2.ClH.H2O/c7-5(6(10)11)1-4-2-8-3-9-4;;/h2-3,5H,1,7H2,(H,8,9)(H,10,11);1H;1H2/t5-;;/m0../s1
biological source: human
Quality Level: 200
sterility: __
concentration: __
color: __
antibiotic activity spectrum: __
Mode of action: __
storage temp.: __
SMILES string: __
InChI: __
