I7018
3-Isobutyl-1-methylxanthine
≥99%, BioUltra
Manufacturer: Sigma Aldrich
CAS Number: 28822-58-4
Synonym(S): 1-Methyl-3-isobutylxanthine, 3,7-Dihydro-1-methyl-3-(2-methylpropyl)-1H-purine-2,6-dione, 3-Isobutyl-1-methyl-2,6(1H,3H)-purinedione, IBMX
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 100 MG | I7018-100-MG | In Stock | ₹ 12,565.20 |
| 250 MG | I7018-250-MG | In Stock | ₹ 25,030.50 |
| 1 G | I7018-1-G | In Stock | ₹ 69,519.30 |
I7018 - 100 MG
In Stock
Quantity
1
Base Price: ₹ 12,565.20
GST (18%): ₹ 2,261.736
Total Price: ₹ 14,826.936
product line
BioUltra
Quality Level
200
Assay
≥99%
impurities
<0.005% Phosphorus (P)
ign. residue
<0.1%
mp
200-201 °C (lit.)
solubility
DMSO: soluble 1 M (with gentle warming)
anion traces
sulfate (SO42-): <0.05%
cation traces
Al: <0.0005%Ca: <0.005%Cu: <0.0005%Fe: <0.005%K: <0.05%Mg: <0.005%NH4+: <0.05%Na: <0.005%Pb: <0.001%Zn: <0.0005%
storage temp.
−20°C
Other Options
Related Products
Description
- Application: 3-Isobutyl-1-methylxanthine, an inhibitor of adenosine 3′,5′-cyclic monophosphate phosphodiesterase (cAMP PDE), has been used:for adipogenic differentiation[1]in tissue culture[2]3T3-L1 preadipocyte differentiation([3]
- Biochem/physiol Actions: The increase in cAMP level as a result of phosphodiesterase inhibition by IBMX activates PKA, leading to decreased proliferation, increased differentiation, and induction of apoptosis. IBMX inhibits phenylephrine-induced release of 5-hydroxytryptamine from neuroendocrine epithelial cells of the airway mucosa (IC50: 1.3 μM). IBMX also serves as an adenosine receptor antagonist. IBMX has been shown to inhibit ion channels in the neuromuscular junction, GH3 cells, and vascular smooth muscle cells. IBMX induces calcium release from intracellular stores in sensory neurons.
- Features and Benefits: Trace element testing by ICPICP testing for trace sulfur (as sulfate) and phosphorus (as phosphate) contentIon chromatography testing for trace ammonium content
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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product line: BioUltra
Quality Level: 200
Assay: ≥99%
impurities: <0.005% Phosphorus (P)
ign. residue: <0.1%
mp: 200-201 °C (lit.)
solubility: DMSO: soluble 1 M (with gentle warming)
anion traces: sulfate (SO42-): <0.05%
cation traces: Al: <0.0005%Ca: <0.005%Cu: <0.0005%Fe: <0.005%K: <0.05%Mg: <0.005%NH4+: <0.05%Na: <0.005%Pb: <0.001%Zn: <0.0005%
storage temp.: −20°C
product line:
BioUltra
Quality Level:
200
Assay:
≥99%
impurities:
<0.005% Phosphorus (P)
ign. residue:
<0.1%
mp:
200-201 °C (lit.)
solubility:
DMSO: soluble 1 M (with gentle warming)
anion traces:
sulfate (SO42-): <0.05%
cation traces:
Al: <0.0005%Ca: <0.005%Cu: <0.0005%Fe: <0.005%K: <0.05%Mg: <0.005%NH4+: <0.05%Na: <0.005%Pb: <0.001%Zn: <0.0005%
storage temp.:
−20°C
product line: __
Quality Level: 200
Assay: ≥99% (HPLC)
impurities: __
ign. residue: __
mp: 194 °C (lit.)
solubility: 1 N NH4OH: 50 mg/mL, clear to very slightly hazy, colorless to light yellow
anion traces: __
cation traces: __
storage temp.: 2-8°C
product line:
__
Quality Level:
200
Assay:
≥99% (HPLC)
impurities:
__
ign. residue:
__
mp:
194 °C (lit.)
solubility:
1 N NH4OH: 50 mg/mL, clear to very slightly hazy, colorless to light yellow
anion traces:
__
cation traces:
__
storage temp.:
2-8°C
product line: __
Quality Level: 100
Assay: 98%
impurities: __
ign. residue: __
mp: 21-24 °C (lit.)
solubility: __
anion traces: __
cation traces: __
storage temp.: 2-8°C
product line:
__
Quality Level:
100
Assay:
98%
impurities:
__
ign. residue:
__
mp:
21-24 °C (lit.)
solubility:
__
anion traces:
__
cation traces:
__
storage temp.:
2-8°C
product line: __
Quality Level: __
Assay: __
impurities: __
ign. residue: __
mp: __
solubility: __
anion traces: __
cation traces: __
storage temp.: __
product line:
__
Quality Level:
__
Assay:
__
impurities:
__
ign. residue:
__
mp:
__
solubility:
__
anion traces:
__
cation traces:
__
storage temp.:
__