MAK154

Fluorometric Sphingomyelin Assay Kit

sufficient for 100 fluorometric tests

Manufacturer: Sigma Aldrich

Select a Size

Pack Size SKU Availability Price
1 KIT MAK154-1-KIT In Stock ₹ 46,109.40

MAK154 - 1 KIT

₹ 46,109.40

In Stock

Quantity

1

Base Price: ₹ 46,109.40

GST (18%): ₹ 8,299.692

Total Price: ₹ 54,409.092

usage

sufficient for 100 fluorometric tests

detection method

fluorometric

relevant disease(s)

cancer

storage temp.

−20°C

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Description

  • General description: Sphinogmyelin, a sphingolipid consisting of a phospholipid (typically phosphocholine) attached to a ceramide moiety, is a major component of cellular membranes. Sphingomylein is enriched in the exoplasmic leaflet of the cell membrane. Within the cell membrane, sphingomyelin interacts with cholesterol to form lipid rafts. The metabolism of sphingomyelin contributes to cellular signaling via the release of ceramide, a second messenger that participates in multiple cellular signaling pathways. Sphingomyelin accumulates in Niemann-Pick disease due to deficiencies in sphingomyelinase activity.
  • Suitability: This kit is suitable for the detection of sphingomyelin in a variety of samples such as blood and cell extracts.
  • Principle: Sphingomyelin is determined by a coupled enzyme assay, in which the hydrolysis of sphingomyelin by sphingomyelinase produces phosphocholine, which results in a fluorescent product (λex =540/λem = 590 nm) proportional to the Sphingomyelin present.

SAFETY INFORMATION

Pictograms

GHS08,GHS05,GHS07,GHS09

Signal Word

Danger

Hazard Statements

H302,H317,H318,H334,H410

Precautionary Statements

P261 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Resp. Sens. 1 - Skin Sens. 1

WGK

WGK 3

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