MAK145
Fluorometric Intracellular Ros Kit
sufficient for 200 fluorometric tests (red)
Manufacturer: Sigma Aldrich
Synonym(S): Intracellular ROS Fluorescence Assay
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 KIT | MAK145-1-KIT | In Stock | ₹ 30,636.00 |
MAK145 - 1 KIT
In Stock
Quantity
1
Base Price: ₹ 30,636.00
GST (18%): ₹ 5,514.48
Total Price: ₹ 36,150.48
usage
sufficient for 200 fluorometric tests (red)
detection method
fluorometric
relevant disease(s)
neurological disorders; cancer
storage temp.
−20°C
Related Products
Description
- General description: Reactive oxygen species (ROS) are generated as a result of the reduction of oxygen during aerobic respiration and by various enzymatic systems within the cell. At physiological levels, ROS contribute to cell signaling and host defense.[1] Increased ROS generation, above the detoxification capacity of the biological system, results in oxidative stress and cellular damage. The main damage to cells results from the ROS-induced alteration of macromolecules such as polyunsaturated fatty acids in membrane lipids, essential proteins, and DNA.[1] ROS has been implicated in disease states, such as Alzheimer′s disease, Parkinson′s disease, cancer, and aging.[2]
- Application: Fluorometric intracellular reactive oxygen species (ROS) Kit has been used for detection of intracellular ROS in live cells.[3][4][5][6]
- Suitability: This kit is suitable for the detection of intracellular ROS by fluorescence microplate reader or a fluorescent microscope.
- Principle: The kit provides a sensitive, one-step fluorometric assay to detect intracellular ROS (especially superoxide and hydroxyl radicals) in live cells within 1 hour incubation. ROS react with a cell-permeable sensor, resulting in a fluorometric product (λex = 520/λem = 605 nm) proportional to the amount of ROS present The assay can be performed in either a 96 or 384 multiwell plate format using a fluorescence microplate reader.
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Compare Similar Items
Show Difference
usage: sufficient for 200 fluorometric tests (red)
detection method: fluorometric
relevant disease(s): neurological disorders; cancer
storage temp.: −20°C
usage:
sufficient for 200 fluorometric tests (red)
detection method:
fluorometric
relevant disease(s):
neurological disorders; cancer
storage temp.:
−20°C
usage: sufficient for 500 fluorometric tests (orange fluorescence, microplate readers)
detection method: fluorometric
relevant disease(s): cancer
storage temp.: −20°C
usage:
sufficient for 500 fluorometric tests (orange fluorescence, microplate readers)
detection method:
fluorometric
relevant disease(s):
cancer
storage temp.:
−20°C
usage: sufficient for 200 colorimetric tests
detection method: colorimetric
relevant disease(s): rheumatological diseases; cancer
storage temp.: −20°C
usage:
sufficient for 200 colorimetric tests
detection method:
colorimetric
relevant disease(s):
rheumatological diseases; cancer
storage temp.:
−20°C
usage: sufficient for 100 fluorometric tests
detection method: fluorometric
relevant disease(s): cancer
storage temp.: −20°C
usage:
sufficient for 100 fluorometric tests
detection method:
fluorometric
relevant disease(s):
cancer
storage temp.:
−20°C