MAK152
Colorimetric Sphingomyelinase Assay Kit
sufficient for 200 colorimetric tests
Manufacturer: Sigma Aldrich
Synonym(S): Neutral Sphingomyelinase Assay Kit
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 KIT | MAK152-1-KIT | In Stock | ₹ 30,636.00 |
MAK152 - 1 KIT
In Stock
Quantity
1
Base Price: ₹ 30,636.00
GST (18%): ₹ 5,514.48
Total Price: ₹ 36,150.48
usage
sufficient for 200 colorimetric tests
detection method
colorimetric
relevant disease(s)
rheumatological diseases; cancer
storage temp.
−20°C
Gene Information
human ... SMPD2(6610) , SMPD3(55512) , SMPD4(55627) mouse ... SMPD2(20598) , SMPD3(58994) , SMPD4(77626) rat ... SMPD2(83537) , SMPD3(94338) , SMPD4(303790)
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Description
- General description: Sphingomyelinase (SMase), or sphingomyelin phosphodiesterase, catalyzes the hydrolytic cleavage of sphingolipid to phosphocholine and ceramide, a second messenger involved in multiple cellular responses including the cellular response to stress. There are at least 5 types of SMases identified which are classified according to their cation dependence, cellular location, and pH optima for activity and include the acidic and neutral sphingomyelinase. Neutral SMases, along with the acidic SMases, are thought to be major contributors to the production of ceramide in response to cellular stress.
- Features and Benefits: Compatible with high-throughput handling systems.
- Suitability: This kit is suitable for the detection of sphingomyelinase activity in a variety of samples such as blood and cell extracts or for screening sphingomyelinase inhibitors and activators.
- Principle: The Sphingomyelinase Assay Kit provides a simple and direct procedure for measuring neutral SMase activity in a variety of samples such as blood or cell extracts, or for screening SMase activators and inhibitors. SMase activity is determined by a coupled enzyme assay, which results in a colorimetric (655 nm) product proportional to the SMase activity present.
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
P261 - P273 - P280 - P302 + P352 - P304 + P340 + P312 - P305 + P351 + P338
Hazard Classifications
Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Resp. Sens. 1 - Skin Sens. 1
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usage: sufficient for 200 colorimetric tests
detection method: colorimetric
relevant disease(s): rheumatological diseases; cancer
storage temp.: −20°C
Gene Information: human ... SMPD2(6610) , SMPD3(55512) , SMPD4(55627) mouse ... SMPD2(20598) , SMPD3(58994) , SMPD4(77626) rat ... SMPD2(83537) , SMPD3(94338) , SMPD4(303790)
usage:
sufficient for 200 colorimetric tests
detection method:
colorimetric
relevant disease(s):
rheumatological diseases; cancer
storage temp.:
−20°C
Gene Information:
human ... SMPD2(6610) , SMPD3(55512) , SMPD4(55627) mouse ... SMPD2(20598) , SMPD3(58994) , SMPD4(77626) rat ... SMPD2(83537) , SMPD3(94338) , SMPD4(303790)
usage: sufficient for 100 fluorometric tests
detection method: fluorometric
relevant disease(s): cancer
storage temp.: −20°C
Gene Information: __
usage:
sufficient for 100 fluorometric tests
detection method:
fluorometric
relevant disease(s):
cancer
storage temp.:
−20°C
Gene Information:
__
usage: sufficient for 100 fluorometric tests
detection method: fluorometric
relevant disease(s): endocrinological disorders, diabetes; gastrointestinal diseases; cancer
storage temp.: −20°C
Gene Information: __
usage:
sufficient for 100 fluorometric tests
detection method:
fluorometric
relevant disease(s):
endocrinological disorders, diabetes; gastrointestinal diseases; cancer
storage temp.:
−20°C
Gene Information:
__
usage: sufficient for 100 fluorometric tests (flow cytometry)
detection method: fluorometric
relevant disease(s): cancer
storage temp.: −20°C
Gene Information: __
usage:
sufficient for 100 fluorometric tests (flow cytometry)
detection method:
fluorometric
relevant disease(s):
cancer
storage temp.:
−20°C
Gene Information:
__